| November 16, 2042 | TOWSON TIGERS | W 94-82 | 1-0 | Z. Carrillo 23 | D. Moore 8 | Z. Carrillo 6 |
| November 19, 2042 | @ UTSA Roadrunners | L 73-78 | 1-1 | L. Layne 13 | D. Moore 5 | L. Holden 6 |
| November 21, 2042 | @ Louisiana Tech Bulldogs | L 61-83 | 1-2 | G. McMahon 12 | D. Moore 6 | L. Layne 7 |
| November 25, 2042 | MISSOURI STATE BEARS | W 102-82 | 2-2 | L. Layne 23 | D. Moore 8 | Z. Carrillo 8 |
| November 29, 2042 | @ St. Bonaventure Bonnies | W 81-71 | 3-2 | L. Layne 19 | D. Moore 8 | Z. Carrillo 10 |
| December 3, 2042 | @ Dartmouth Big Green | L 68-79 | 3-3 | D. Bradley 13 | D. Moore 3 | Z. Carrillo 8 |
| December 7, 2042 | @ Wisconsin Badgers | W 67-66 | 4-3 | Z. Carrillo 12 | D. Moore 4 | G. McMahon 10 |
| December 8, 2042 | @ Prairie View Panthers | W 87-74 | 5-3 | Z. Carrillo 21 | D. Moore 10 | Z. Carrillo 8 |
| December 13, 2042 | AIR FORCE FALCONS | L 77-91 | 5-4 | L. Layne 13 | D. Moore 5 | L. Layne 7 |
| December 21, 2042 | PENNSYLVANIA QUAKERS | L 93-97 OT | 5-5 | D. Moore 15 | D. Moore 8 | Z. Carrillo 11 |
| December 28, 2042 | @ Campbell Camels | L 88-96 | 5-6 | G. McMahon 19 | D. Moore 4 | L. Holden 6 |
| January 2, 2043 | LEHIGH MOUNTAIN HAWKS* | W 86-70 | 6-6 | G. McMahon 15 | D. Moore 5 | L. Holden 11 |
| January 5, 2043 | @ Lafayette Leopards* | W 70-56 | 7-6 | L. Layne 19 | D. Moore 11 | L. Holden 12 |
| January 9, 2043 | BOSTON UNIVERSITY TERRIERS* | L 73-80 | 7-7 | D. Moore 17 | G. McMahon 5 | D. Bradley 8 |
| January 12, 2043 | @ Loyola Maryland Greyhounds* | W 86-64 | 8-7 | D. Moore 16 | L. Layne 5 | D. Bradley 8 |
| January 16, 2043 | NAVY MIDSHIPMEN* | W 85-71 | 9-7 | G. McMahon 16 | D. Moore 7 | Z. Carrillo 6 |
| January 19, 2043 | @ Bucknell Bison* | L 64-84 | 9-8 | Z. Carrillo 10 | D. Moore 3 | L. Holden 8 |
| January 23, 2043 | AMERICAN EAGLES* | W 75-56 | 10-8 | L. Layne 17 | D. Moore 6 | Z. Carrillo 11 |
| January 26, 2043 | @ Colgate Raiders* | L 63-83 | 10-9 | G. McMahon 13 | D. Moore 9 | L. Layne 6 |
| January 30, 2043 | HOLY CROSS CRUSADERS* | L 80-82 OT | 10-10 | Z. Carrillo 18 | D. Moore 6 | L. Holden 9 |
| February 2, 2043 | @ Lehigh Mountain Hawks* | L 70-72 | 10-11 | D. Moore 21 | L. Layne 5 | W. Powell 6 |
| February 6, 2043 | LAFAYETTE LEOPARDS* | W 80-65 | 11-11 | D. Moore 16 | D. Moore 8 | L. Holden 12 |
| February 9, 2043 | @ Boston University Terriers* | L 67-89 | 11-12 | D. Moore 16 | D. Moore 7 | L. Holden 6 |
| February 13, 2043 | LOYOLA MARYLAND GREYHOUNDS* | W 90-72 OT | 12-12 | L. Layne 23 | D. Moore 8 | L. Holden 11 |
| February 16, 2043 | @ Navy Midshipmen* | W 77-54 | 13-12 | G. McMahon 14 | D. Moore 3 | L. Holden 9 |
| February 20, 2043 | BUCKNELL BISON* | L 62-73 | 13-13 | L. Holden 13 | L. Layne 6 | L. Layne 9 |
| February 23, 2043 | @ American Eagles* | L 65-101 | 13-14 | L. Layne 13 | D. Moore 3 | D. Moore 6 |
| February 27, 2043 | COLGATE RAIDERS* | L 75-85 | 13-15 | L. Layne 16 | D. Moore 7 | L. Holden 12 |
| March 2, 2043 | @ Holy Cross Crusaders* | L 66-85 | 13-16 | Z. Carrillo 18 | D. Moore 4 | L. Holden 8 |
| March 6, 2043 | @ Colgate Raiders Patriot League Tournament | L 69-79 | 13-17 | D. Moore 14 | D. Moore 7 | G. McMahon 7 |
