| November 14, 2042 | IONA GAELS NIT Season Tip-Off | W 94-88 | 1-0 | W. Minton 26 | A. Strickland 6 | S. Hester 9 |
| November 16, 2042 | SAN DIEGO STATE AZTECS NIT Season Tip-Off | W 87-68 | 2-0 | S. Hester 20 | A. Strickland 7 | S. Hester 10 |
| November 18, 2042 | #20 SAINT MARY'S GAELS NIT Season Tip-Off | W 74-61 | 3-0 | A. Strickland 15 | W. Minton 5 | S. Hester 10 |
| November 20, 2042 | #3 NOTRE DAME FIGHTING IRISH NIT Season Tip-Off | L 78-87 | 3-1 | B. Jeffries 15 | B. Jeffries 5 | N. Caspers 10 |
| November 21, 2042 | ARKANSAS RAZORBACKS | W 81-55 | 4-1 | B. Jeffries 20 | B. Jeffries 5 | B. Jeffries 15 |
| November 24, 2042 | VIRGINIA CAVALIERS | W 68-58 | 5-1 | S. Hester 21 | A. Strickland 5 | S. Hester 13 |
| November 28, 2042 | @ UAB Blazers | W 87-53 | 6-1 | B. Jeffries 18 | A. Strickland 11 | B. Jeffries 19 |
| December 1, 2042 | STEPHEN F. AUSTIN LUMBERJACKS | W 79-56 | 7-1 | W. Minton 22 | A. Strickland 8 | S. Hester 10 |
| December 5, 2042 | #22 GEORGIA TECH YELLOW JACKETS | W 88-74 | 8-1 | B. Jeffries 18 | A. Strickland 4 | B. Jeffries 17 |
| December 13, 2042 | #23 TEXAS LONGHORNS | W 92-74 | 9-1 | W. Minton 28 | T. Haney 5 | B. Jeffries 7 |
| December 15, 2042 | TOLEDO ROCKETS | W 90-74 | 10-1 | S. Hester 23 | A. Strickland 4 | B. Jeffries 9 |
| December 19, 2042 | CHARLOTTE 49ERS | W 91-65 | 11-1 | W. Minton 20 | A. Strickland 6 | S. Hester 12 |
| December 26, 2042 | @ Arizona Wildcats* | W 88-73 | 12-1 | S. Hester 21 | A. Strickland 6 | S. Hester 14 |
| December 30, 2042 | #2 KANSAS JAYHAWKS* | W 87-86 | 13-1 | S. Hester 22 | A. Strickland 4 | S. Hester 13 |
| January 2, 2043 | ARIZONA STATE SUN DEVILS* | W 87-66 | 14-1 | S. Hester 34 | A. Strickland 7 | S. Hester 13 |
| January 6, 2043 | @ #24 Houston Cougars* | W 89-76 | 15-1 | A. Strickland 19 | W. Minton 7 | B. Jeffries 16 |
| January 11, 2043 | TCU HORNED FROGS* | W 79-61 | 16-1 | S. Hester 21 | A. Strickland 5 | B. Jeffries 17 |
| January 13, 2043 | @ #9 West Virginia Mountaineers* | W 79-64 | 17-1 | S. Hester 18 | A. Strickland 6 | S. Hester 14 |
| January 18, 2043 | UTAH UTES* | W 83-59 | 18-1 | B. Jeffries 22 | A. Strickland 5 | B. Jeffries 14 |
| January 20, 2043 | @ UCF Knights* | L 71-80 | 18-2 | B. Jeffries 14 | A. Strickland 3 | B. Jeffries 19 |
| January 25, 2043 | @ TCU Horned Frogs* | W 97-88 | 19-2 | W. Minton 29 | A. Strickland 9 | B. Jeffries 18 |
| January 27, 2043 | BYU COUGARS* | L 85-86 | 19-3 | S. Hester 18 | T. Haney 7 | S. Hester 10 |
| February 1, 2043 | ARIZONA WILDCATS* | W 94-68 | 20-3 | A. Strickland 23 | A. Strickland 8 | E. Mello 12 |
| February 3, 2043 | @ Kansas State Wildcats* | W 90-71 | 21-3 | W. Minton 23 | W. Minton 5 | B. Jeffries 19 |
| February 6, 2043 | COLORADO BUFFALOES* | W 90-61 | 22-3 | S. Hester 19 | W. Minton 5 | B. Jeffries 12 |
| February 10, 2043 | @ Cincinnati Bearcats* | W 82-70 | 23-3 | S. Hester 19 | A. Strickland 6 | B. Jeffries 15 |
| February 15, 2043 | @ Iowa State Cyclones (3-20, 1-13, 3-10 Home)* | - | | | | |
| February 17, 2043 | TEXAS TECH RED RAIDERS (10-14, 4-10, 3-7 Away)* | - | | | | |
| February 20, 2043 | @ BYU Cougars (15-9, 8-6, 10-2 Home)* | - | | | | |
| February 24, 2043 | OKLAHOMA STATE COWBOYS (15-10, 5-9, 2-5 Away)* | - | | | | |
| February 27, 2043 | UCF KNIGHTS (14-9, 9-5, 3-7 Away)* | - | | | | |
| March 3, 2043 | @ Colorado Buffaloes (13-11, 7-7, 8-5 Home)* | - | | | | |
