| November 16, 2042 | @ Omaha Mavericks | L 74-75 | 0-1 | S. Cooper 28 | S. Cooper 7 | V. Freeman 7 |
| November 18, 2042 | @ Nebraska Cornhuskers Emerald Coast Classic | W 75-64 | 1-1 | H. Yeaton 17 | S. Cooper 6 | S. Cooper 6 |
| November 19, 2042 | @ #19 Connecticut Huskies Emerald Coast Classic | L 61-77 | 1-2 | H. Yeaton 21 | S. Cooper 4 | V. Freeman 11 |
| November 23, 2042 | COLUMBIA LIONS | W 74-65 | 2-2 | S. Cooper 16 | S. Cooper 3 | J. Sanders 7 |
| November 25, 2042 | @ UMBC Retrievers | W 83-82 | 3-2 | S. Cooper 19 | S. Cooper 9 | P. Street 9 |
| December 2, 2042 | @ Tennessee Volunteers | W 73-64 | 4-2 | J. English 17 | S. Cooper 9 | J. Sanders 12 |
| December 6, 2042 | @ Western Illinois Leathernecks | W 83-70 | 5-2 | H. Yeaton 29 | S. Cooper 6 | H. Yeaton 10 |
| December 10, 2042 | @ North Dakota St. Bison | W 76-65 | 6-2 | S. Cooper 17 | S. Cooper 5 | H. Yeaton 12 |
| December 13, 2042 | LIPSCOMB BISONS | W 79-65 | 7-2 | H. Yeaton 24 | J. English 5 | H. Yeaton 6 |
| December 20, 2042 | @ Little Rock Trojans | L 70-75 | 7-3 | V. Freeman 18 | J. English 5 | V. Freeman 8 |
| December 26, 2042 | @ Evansville Purple Aces* | L 65-67 | 7-4 | H. Yeaton 19 | S. Cooper 5 | V. Freeman 8 |
| December 29, 2042 | @ Drake Bulldogs* | W 88-67 | 8-4 | J. Sanders 16 | S. Cooper 5 | H. Yeaton 10 |
| January 2, 2043 | @ Missouri State Bears* | W 81-78 | 9-4 | A. Croshere 18 | S. Cooper 5 | H. Yeaton 8 |
| January 5, 2043 | @ Indiana State Sycamores* | L 63-86 | 9-5 | J. Sanders 14 | S. Cooper 4 | J. Sanders 8 |
| January 9, 2043 | MURRAY STATE RACERS* | L 59-79 | 9-6 | S. Cooper 15 | H. Yeaton 3 | H. Yeaton 11 |
| January 12, 2043 | BRADLEY BRAVES* | L 69-78 | 9-7 | J. Stokes 26 | S. Cooper 7 | H. Yeaton 11 |
| January 16, 2043 | SOUTHERN ILLINOIS SALUKIS* | L 73-76 | 9-8 | S. Cooper 27 | D. Glynn 3 | H. Yeaton 7 |
| January 19, 2043 | @ UIC Flames* | L 57-84 | 9-9 | J. Stokes 21 | S. Cooper 3 | V. Freeman 12 |
| January 23, 2043 | @ Northern Iowa Panthers* | W 83-66 | 10-9 | J. Stokes 41 | S. Cooper 9 | H. Yeaton 11 |
| January 26, 2043 | @ Illinois State Redbirds* | W 69-67 | 11-9 | V. Freeman 14 | S. Cooper 5 | V. Freeman 13 |
| January 30, 2043 | UIC FLAMES* | L 67-77 | 11-10 | H. Yeaton 17 | H. Yeaton 3 | V. Freeman 9 |
| February 2, 2043 | NORTHERN IOWA PANTHERS* | L 89-94 | 11-11 | J. Stokes 15 | S. Cooper 7 | V. Freeman 11 |
| February 6, 2043 | @ Bradley Braves* | L 59-69 | 11-12 | P. Street 11 | S. Cooper 4 | V. Freeman 13 |
| February 9, 2043 | @ Southern Illinois Salukis* | L 56-86 | 11-13 | J. Stokes 12 | S. Cooper 4 | H. Yeaton 6 |
| February 13, 2043 | MISSOURI STATE BEARS (9-15, 4-10, 6-8 Away)* | - | | | | |
| February 16, 2043 | INDIANA STATE SYCAMORES (19-6, 11-3, 6-5 Away)* | - | | | | |
| February 20, 2043 | EVANSVILLE PURPLE ACES (16-7, 11-3, 9-2 Away)* | - | | | | |
| February 23, 2043 | DRAKE BULLDOGS (6-17, 6-8, 2-8 Away)* | - | | | | |
| February 27, 2043 | ILLINOIS STATE REDBIRDS (10-13, 7-7, 3-9 Away)* | - | | | | |
| March 2, 2043 | @ Valparaiso Crusaders (11-12, 5-9, 7-5 Home)* | - | | | | |
