| November 13, 2042 | @ UIC Flames | L 65-72 | 0-1 | A. Mays 12 | K. Burke 4 | H. Hurd 5 |
| November 15, 2042 | @ Hofstra Pride | L 82-95 OT | 0-2 | D. Smart 26 | K. Burke 4 | D. Smart 9 |
| November 18, 2042 | @ Saint Joseph's Hawks | W 79-78 | 1-2 | D. Smart 19 | K. Burke 6 | A. Mays 8 |
| November 22, 2042 | @ Iowa State Cyclones | W 83-76 | 2-2 | S. Sexton 18 | K. Burke 8 | D. Smart 9 |
| November 25, 2042 | @ UC Davis Aggies | L 69-74 | 2-3 | D. Smart 11 | K. Burke 6 | H. Hurd 8 |
| November 29, 2042 | BUCKNELL BISON | W 98-69 | 3-3 | D. Smart 22 | K. Burke 7 | A. Mays 10 |
| December 2, 2042 | @ Dayton Flyers | W 91-84 | 4-3 | S. Sexton 21 | K. Burke 4 | A. Mays 11 |
| December 6, 2042 | WILLIAM & MARY TRIBE | W 88-79 | 5-3 | D. Smart 28 | K. Burke 10 | A. Mays 9 |
| December 9, 2042 | HOWARD BISON | W 87-83 | 6-3 | D. Smart 20 | K. Burke 9 | H. Hurd 8 |
| December 13, 2042 | @ Cornell Big Red | L 37-80 | 6-4 | S. Sexton 8 | K. Burke 2 | S. Sexton 7 |
| December 17, 2042 | @ Kansas City Kangaroos | L 68-80 | 6-5 | D. Smart 13 | K. Burke 2 | H. Hurd 11 |
| December 20, 2042 | UL MONROE WARHAWKS | W 74-56 | 7-5 | D. Smart 15 | K. Burke 5 | S. Sexton 10 |
| December 23, 2042 | @ Canisius Golden Griffins | W 70-60 | 8-5 | D. Smart 11 | K. Burke 6 | S. Sexton 9 |
| January 3, 2043 | VERMONT CATAMOUNTS* | W 93-80 | 9-5 | S. Sexton 14 | K. Burke 7 | S. Sexton 10 |
| January 10, 2043 | @ NJIT Highlanders* | L 64-86 | 9-6 | D. Blue 12 | K. Burke 4 | H. Hurd 5 |
| January 13, 2043 | BRYANT BULLDOGS* | W 86-77 | 10-6 | D. Smart 17 | K. Burke 4 | S. Sexton 8 |
| January 17, 2043 | @ New Hampshire Wildcats* | L 74-94 | 10-7 | S. Sexton 12 | D. Smart 4 | S. Sexton 8 |
| January 20, 2043 | ALBANY GREAT DANES* | W 91-67 | 11-7 | D. Smart 21 | K. Burke 15 | A. Mays 10 |
| January 24, 2043 | @ UMBC Retrievers* | L 56-84 | 11-8 | S. Sexton 16 | K. Burke 8 | H. Hurd 5 |
| January 27, 2043 | UMASS LOWELL RIVER HAWKS* | W 75-65 | 12-8 | D. Smart 12 | K. Burke 6 | A. Mays 10 |
| January 31, 2043 | @ Maine Black Bears* | W 81-66 | 13-8 | D. Smart 24 | K. Burke 6 | S. Sexton 11 |
| February 3, 2043 | @ Vermont Catamounts* | L 64-94 | 13-9 | S. Sexton 9 | K. Burke 3 | A. Mays 9 |
| February 10, 2043 | NJIT HIGHLANDERS* | L 67-77 | 13-10 | D. Smart 21 | K. Burke 3 | S. Sexton 10 |
| February 14, 2043 | @ Bryant Bulldogs* | L 72-84 | 13-11 | D. Smart 16 | K. Burke 8 | S. Sexton 8 |
| February 17, 2043 | NEW HAMPSHIRE WILDCATS* | W 87-76 | 14-11 | B. Fleming 22 | K. Burke 4 | K. Eason 8 |
| February 21, 2043 | @ Albany Great Danes* | W 73-65 | 15-11 | D. Smart 20 | K. Burke 4 | S. Sexton 8 |
| February 24, 2043 | UMBC RETRIEVERS* | W 72-67 | 16-11 | D. Smart 25 | K. Burke 4 | S. Sexton 9 |
| February 28, 2043 | @ UMass Lowell River Hawks* | W 87-71 | 17-11 | H. Hurd 18 | K. Burke 5 | A. Mays 14 |
| March 3, 2043 | MAINE BLACK BEARS* | W 82-69 | 18-11 | S. Sexton 15 | K. Burke 5 | A. Mays 8 |
| March 5, 2043 | UMASS LOWELL RIVER HAWKS America East Tournament | W 86-75 | 19-11 | H. Hurd 16 | A. Mays 4 | S. Sexton 8 |
| March 6, 2043 | @ Vermont Catamounts America East Tournament | W 77-71 | 20-11 | D. Smart 19 | K. Burke 4 | S. Sexton 12 |
| March 7, 2043 | @ Bryant Bulldogs America East Tournament | L 71-90 | 20-12 | S. Sexton 24 | K. Burke 3 | S. Sexton 9 |
| March 13, 2043 | @ UMass Minutemen CIT Tournament | L 80-89 | 20-13 | D. Smart 14 | K. Burke 8 | H. Hurd 7 |
