| November 16, 2042 | PENNSYLVANIA QUAKERS | W 70-53 | 1-0 | C. Thompkins 20 | C. Gann 7 | C. Thompkins 11 |
| November 22, 2042 | @ Tennessee Volunteers | L 71-94 | 1-1 | D. McGrath 12 | C. Gann 6 | C. Goodwin 5 |
| November 30, 2042 | APP STATE MOUNTAINEERS | W 92-67 | 2-1 | L. Kerr 16 | C. Gann 7 | R. Williams 9 |
| December 3, 2042 | GEORGETOWN HOYAS | W 84-64 | 3-1 | C. Thompkins 23 | L. Kerr 3 | C. Goodwin 13 |
| December 5, 2042 | NORTHWESTERN WILDCATS | W 75-60 | 4-1 | C. Goodwin 22 | L. Kerr 3 | C. Goodwin 10 |
| December 10, 2042 | @ Michigan Wolverines | W 82-77 | 5-1 | C. Thompkins 13 | C. Gann 4 | C. Thompkins 10 |
| December 13, 2042 | @ #5 Gonzaga Bulldogs | L 76-79 | 5-2 | L. Kerr 15 | C. Gann 4 | D. McGrath 8 |
| December 19, 2042 | SAN DIEGO TOREROS | W 71-56 | 6-2 | L. Kerr 17 | C. Gann 5 | R. Williams 9 |
| December 23, 2042 | CLEMSON TIGERS Gulf Coast Showcase | W 103-92 | 7-2 | L. Kerr 25 | C. Gann 4 | J. Herron 12 |
| December 24, 2042 | @ Michigan State Spartans Gulf Coast Showcase | L 92-97 | 7-3 | C. Thompkins 21 | C. Gann 4 | C. Thompkins 6 |
| December 28, 2042 | WEST VIRGINIA MOUNTAINEERS (9-2, 0-0, 0-1 Away)* | - | | | | |
| December 30, 2042 | @ Utah Utes (7-4, 0-0, 5-3 Home)* | - | | | | |
| January 4, 2043 | @ Kansas Jayhawks (10-1, 0-0, 6-0 Home)* | - | | | | |
| January 6, 2043 | TEXAS TECH RED RAIDERS (6-4, 0-0, 1-2 Away)* | - | | | | |
| January 9, 2043 | @ Houston Cougars (7-2, 0-0, 7-0 Home)* | - | | | | |
| January 13, 2043 | CINCINNATI BEARCATS (8-2, 0-0, 0-0 Away)* | - | | | | |
| January 18, 2043 | @ Oklahoma State Cowboys (10-1, 0-0, 8-0 Home)* | - | | | | |
| January 23, 2043 | ARIZONA WILDCATS (3-6, 0-0, 0-4 Away)* | - | | | | |
| January 25, 2043 | ARIZONA STATE SUN DEVILS (7-3, 0-0, 1-0 Away)* | - | | | | |
| January 27, 2043 | @ Baylor Bears (11-1, 0-0, 7-0 Home)* | - | | | | |
| February 1, 2043 | COLORADO BUFFALOES (6-4, 0-0, 1-1 Away)* | - | | | | |
| February 3, 2043 | @ Cincinnati Bearcats (8-2, 0-0, 6-2 Home)* | - | | | | |
| February 8, 2043 | IOWA STATE CYCLONES (2-7, 0-0, 0-2 Away)* | - | | | | |
| February 10, 2043 | @ Arizona Wildcats (3-6, 0-0, 3-2 Home)* | - | | | | |
| February 15, 2043 | @ Arizona State Sun Devils (7-3, 0-0, 5-2 Home)* | - | | | | |
| February 17, 2043 | TCU HORNED FROGS (7-3, 0-0, 0-2 Away)* | - | | | | |
| February 20, 2043 | BAYLOR BEARS (11-1, 0-0, 1-0 Away)* | - | | | | |
| February 24, 2043 | @ UCF Knights (5-4, 0-0, 5-0 Home)* | - | | | | |
| March 1, 2043 | KANSAS STATE WILDCATS (5-5, 0-0, 1-1 Away)* | - | | | | |
| March 3, 2043 | @ Iowa State Cyclones (2-7, 0-0, 2-4 Home)* | - | | | | |
