| November 16, 2042 | @ NC State Wolfpack | L 58-74 | 0-1 | M. Fahey 11 | S. Ashley 4 | B. Taylor 10 |
| November 17, 2042 | LAFAYETTE LEOPARDS | W 74-65 | 1-1 | H. Hansen 13 | S. Ashley 6 | B. Taylor 8 |
| November 21, 2042 | @ #22 UCLA Bruins WSSN Classic | L 75-86 | 1-2 | B. Taylor 23 | S. Ashley 4 | B. Taylor 7 |
| November 24, 2042 | @ #10 Wichita State Shockers | L 70-87 | 1-3 | B. Taylor 18 | S. Ashley 8 | B. Taylor 8 |
| November 29, 2042 | TENNESSEE VOLUNTEERS | W 82-59 | 2-3 | A. Moon 21 | S. Ashley 4 | A. Moon 11 |
| December 5, 2042 | MILWAUKEE PANTHERS | W 64-40 | 3-3 | A. Moon 18 | S. Ashley 3 | A. Moon 12 |
| December 13, 2042 | @ South Florida Bulls | L 62-78 | 3-4 | A. Moon 16 | S. Ashley 5 | B. Taylor 10 |
| December 17, 2042 | UNLV RUNNIN' REBELS | W 93-76 | 4-4 | H. Hansen 29 | S. Ashley 8 | H. Hansen 6 |
| December 19, 2042 | GARDNER-WEBB RUNNIN' BULLDOGS | W 77-55 | 5-4 | A. Moon 20 | S. Ashley 7 | B. Taylor 11 |
| December 28, 2042 | TCU HORNED FROGS* | L 66-86 | 5-5 | A. Moon 17 | H. Hansen 5 | A. Moon 9 |
| January 2, 2043 | @ #11 West Virginia Mountaineers* | L 70-86 | 5-6 | A. Moon 21 | S. Ashley 4 | A. Moon 7 |
| January 4, 2043 | IOWA STATE CYCLONES* | W 89-59 | 6-6 | M. Fahey 19 | S. Ashley 8 | A. Moon 11 |
| January 6, 2043 | @ #12 Oklahoma State Cowboys* | W 101-92 | 7-6 | B. Taylor 20 | M. Fahey 4 | B. Taylor 13 |
| January 11, 2043 | @ Texas Tech Red Raiders* | W 79-64 | 8-6 | S. Ashley 19 | S. Ashley 5 | B. Taylor 7 |
| January 13, 2043 | HOUSTON COUGARS* | W 76-75 | 9-6 | S. Ashley 19 | S. Ashley 7 | B. Taylor 14 |
| January 18, 2043 | @ Arizona State Sun Devils* | L 82-88 | 9-7 | H. Hansen 19 | S. Ashley 4 | B. Taylor 10 |
| January 20, 2043 | #1 BAYLOR BEARS* | W 80-71 | 10-7 | S. Ashley 15 | S. Ashley 8 | B. Taylor 10 |
| January 25, 2043 | #10 WEST VIRGINIA MOUNTAINEERS* | W 74-58 | 11-7 | M. Fahey 24 | H. Hansen 6 | B. Taylor 9 |
| January 27, 2043 | @ Colorado Buffaloes* | L 75-95 | 11-8 | S. Ashley 15 | S. Ashley 5 | B. Taylor 13 |
| January 30, 2043 | TEXAS TECH RED RAIDERS* | W 77-57 | 12-8 | S. Ashley 22 | M. Fahey 5 | B. Taylor 12 |
| February 3, 2043 | @ #23 Houston Cougars* | W 70-59 | 13-8 | S. Ashley 21 | M. Fahey 7 | H. Hansen 8 |
| February 8, 2043 | KANSAS STATE WILDCATS* | W 72-64 | 14-8 | M. Fahey 19 | S. Ashley 4 | A. Moon 10 |
| February 10, 2043 | @ Utah Utes* | L 69-84 | 14-9 | S. Ashley 21 | S. Ashley 7 | B. Taylor 11 |
| February 15, 2043 | @ Kansas Jayhawks (20-5, 10-4, 12-1 Home)* | - | | | | |
| February 17, 2043 | ARIZONA WILDCATS (5-18, 2-12, 0-11 Away)* | - | | | | |
| February 20, 2043 | @ Kansas State Wildcats (11-14, 6-8, 5-8 Home)* | - | | | | |
| February 24, 2043 | BYU COUGARS (15-9, 8-6, 4-6 Away)* | - | | | | |
| February 27, 2043 | @ Baylor Bears (23-3, 12-2, 13-1 Home)* | - | | | | |
| March 3, 2043 | CINCINNATI BEARCATS (13-12, 4-10, 2-5 Away)* | - | | | | |
