| November 15, 2042 | KENT STATE GOLDEN FLASHES | L 66-80 | 0-1 | J. Burns 17 | D. Shoemaker 4 | R. Santos 11 |
| November 19, 2042 | HARVARD CRIMSON | L 103-110 OT | 0-2 | R. Santos 19 | D. Shoemaker 4 | R. Santos 9 |
| November 23, 2042 | CHARLESTON COUGARS | W 74-71 | 1-2 | J. Burns 24 | D. Shoemaker 5 | J. Burns 13 |
| November 29, 2042 | SOUTH CAROLINA UPSTATE SPARTANS | W 68-65 | 2-2 | K. Lampley 14 | D. Shoemaker 4 | J. Burns 10 |
| December 6, 2042 | OKLAHOMA SOONERS | W 87-69 | 3-2 | J. Burns 28 | Q. Holley 7 | R. Santos 8 |
| December 10, 2042 | COLUMBIA LIONS | W 84-68 | 4-2 | Q. Holley 18 | R. Santos 3 | R. Santos 7 |
| December 13, 2042 | #18 XAVIER MUSKETEERS | W 74-66 | 5-2 | J. Burns 20 | B. Jacobson 5 | J. Burns 10 |
| December 21, 2042 | INDIANA HOOSIERS | W 75-60 | 6-2 | Q. Holley 19 | D. Shoemaker 4 | J. Burns 11 |
| December 23, 2042 | AUBURN TIGERS JAG Holiday Invitational | W 80-56 | 7-2 | B. Jacobson 11 | D. Shoemaker 6 | J. Burns 11 |
| December 24, 2042 | @ UAB Blazers JAG Holiday Invitational | W 86-72 | 8-2 | J. Burns 21 | D. Shoemaker 4 | R. Santos 11 |
| December 25, 2042 | @ USC Trojans JAG Holiday Invitational | W 86-78 | 9-2 | Q. Holley 17 | D. Shoemaker 5 | R. Santos 10 |
| December 26, 2042 | ARIZONA STATE SUN DEVILS* | L 66-78 | 9-3 | R. Santos 18 | D. Shoemaker 3 | N. Wateman 8 |
| December 30, 2042 | @ #13 Oklahoma State Cowboys* | L 58-88 | 9-4 | J. Burns 12 | D. Shoemaker 4 | Q. Holley 8 |
| January 4, 2043 | @ TCU Horned Frogs* | L 68-88 | 9-5 | Q. Holley 12 | D. Shoemaker 3 | R. Santos 7 |
| January 6, 2043 | #11 WEST VIRGINIA MOUNTAINEERS* | L 72-81 | 9-6 | D. Shoemaker 18 | B. Jacobson 7 | R. Santos 7 |
| January 9, 2043 | COLORADO BUFFALOES* | W 78-59 | 10-6 | B. Jacobson 17 | D. Shoemaker 6 | J. Burns 8 |
| January 13, 2043 | @ BYU Cougars* | L 74-96 | 10-7 | R. Santos 14 | D. Shoemaker 4 | J. Burns 10 |
| January 18, 2043 | @ Arizona Wildcats* | W 66-59 | 11-7 | K. Lampley 13 | J. Burns 4 | B. Jacobson 7 |
| January 20, 2043 | KANSAS STATE WILDCATS* | W 66-61 | 12-7 | J. Burns 25 | D. Shoemaker 5 | J. Burns 8 |
| January 23, 2043 | TEXAS TECH RED RAIDERS* | L 63-73 | 12-8 | J. Burns 15 | B. Jacobson 3 | R. Santos 8 |
| January 27, 2043 | @ Iowa State Cyclones* | W 81-62 | 13-8 | J. Burns 21 | D. Shoemaker 6 | J. Burns 13 |
| February 1, 2043 | @ #4 Kansas Jayhawks* | L 74-86 | 13-9 | B. Jacobson 14 | D. Shoemaker 6 | N. Wateman 8 |
| February 3, 2043 | BYU COUGARS* | L 76-92 | 13-10 | J. Burns 17 | K. Lampley 3 | R. Santos 8 |
| February 8, 2043 | @ Houston Cougars* | L 60-79 | 13-11 | R. Santos 15 | D. Shoemaker 4 | J. Burns 17 |
| February 10, 2043 | #2 BAYLOR BEARS* | L 70-82 | 13-12 | J. Burns 21 | D. Shoemaker 9 | J. Burns 11 |
| February 13, 2043 | @ Colorado Buffaloes* | L 73-98 | 13-13 | J. Burns 17 | D. Shoemaker 5 | Q. Holley 5 |
| February 17, 2043 | #4 KANSAS JAYHAWKS* | W 80-74 | 14-13 | B. Jacobson 18 | D. Shoemaker 10 | J. Burns 10 |
| February 22, 2043 | UTAH UTES* | W 73-55 | 15-13 | J. Burns 13 | K. Lampley 7 | R. Santos 12 |
| February 24, 2043 | @ Texas Tech Red Raiders* | W 76-53 | 16-13 | J. Burns 11 | T. Haywood 4 | R. Santos 8 |
| March 1, 2043 | IOWA STATE CYCLONES* | W 84-71 | 17-13 | J. Burns 22 | D. Shoemaker 4 | J. Burns 9 |
| March 3, 2043 | @ UCF Knights* | L 73-90 | 17-14 | B. Jacobson 16 | D. Shoemaker 6 | J. Burns 6 |
| March 8, 2043 | TEXAS TECH RED RAIDERS Big 12 Tournament | L 65-72 | 17-15 | J. Burns 16 | D. Shoemaker 5 | J. Burns 9 |
