| November 13, 2042 | INCARNATE WORD CARDINALS Legends Classic | W 101-94 | 1-0 | F. Zabelle 19 | J. McCarthy 5 | L. Barker 11 |
| November 15, 2042 | CHARLOTTE 49ERS Legends Classic | L 69-78 | 1-1 | F. Zabelle 13 | L. Barker 3 | W. Fitzgerald 7 |
| November 25, 2042 | MISSOURI TIGERS | W 72-66 | 2-1 | W. Fitzgerald 17 | J. McCarthy 8 | J. McCarthy 12 |
| November 30, 2042 | @ #16 Florida State Seminoles | L 73-81 | 2-2 | F. Zabelle 20 | J. McCarthy 6 | W. Fitzgerald 5 |
| December 3, 2042 | MICHIGAN STATE SPARTANS | W 87-70 | 3-2 | W. Fitzgerald 22 | J. McCarthy 7 | L. Barker 8 |
| December 7, 2042 | #24 LOUISVILLE CARDINALS | L 84-92 | 3-3 | L. Barker 13 | J. McCarthy 5 | J. McCarthy 6 |
| December 8, 2042 | SANTA CLARA BRONCOS | W 67-63 | 4-3 | W. Fitzgerald 18 | J. McCarthy 4 | W. Fitzgerald 8 |
| December 13, 2042 | COLORADO STATE RAMS | W 86-66 | 5-3 | J. McCarthy 19 | J. McCarthy 4 | W. Fitzgerald 17 |
| December 21, 2042 | #4 WICHITA STATE SHOCKERS | L 68-75 | 5-4 | W. Fitzgerald 14 | W. Fitzgerald 3 | L. Barker 8 |
| December 24, 2042 | @ Nevada Wolfpack | W 74-61 | 6-4 | W. Fitzgerald 14 | L. Barker 9 | B. Green 8 |
| December 28, 2042 | UTAH UTES* | W 84-65 | 7-4 | F. Zabelle 25 | J. McCarthy 8 | F. Zabelle 8 |
| December 30, 2042 | @ Texas Tech Red Raiders* | W 82-59 | 8-4 | W. Fitzgerald 13 | W. Fitzgerald 3 | F. Zabelle 11 |
| January 4, 2043 | #12 OKLAHOMA STATE COWBOYS* | L 72-79 | 8-5 | F. Zabelle 21 | J. McCarthy 4 | F. Zabelle 11 |
| January 6, 2043 | @ Iowa State Cyclones* | L 78-89 | 8-6 | B. Green 14 | J. McCarthy 5 | F. Zabelle 9 |
| January 9, 2043 | @ Cincinnati Bearcats* | L 59-78 | 8-7 | F. Zabelle 14 | J. McCarthy 5 | F. Zabelle 7 |
| January 16, 2043 | ARIZONA STATE SUN DEVILS* | W 86-65 | 9-7 | W. Fitzgerald 15 | F. Zabelle 4 | F. Zabelle 10 |
| January 18, 2043 | HOUSTON COUGARS* | W 81-70 | 10-7 | W. Fitzgerald 15 | J. McCarthy 5 | L. Barker 6 |
| January 20, 2043 | @ Utah Utes* | L 67-77 | 10-8 | L. Barker 16 | B. Green 3 | F. Zabelle 9 |
| January 25, 2043 | @ #3 Kansas Jayhawks* | W 103-97 | 11-8 | I. Zore 18 | J. McCarthy 8 | W. Fitzgerald 7 |
| January 27, 2043 | UCF KNIGHTS* | W 95-75 | 12-8 | W. Fitzgerald 22 | J. McCarthy 4 | B. Green 9 |
| February 1, 2043 | @ BYU Cougars* | W 87-85 | 13-8 | L. Barker 29 | J. McCarthy 10 | F. Zabelle 8 |
| February 3, 2043 | #13 WEST VIRGINIA MOUNTAINEERS* | L 71-85 | 13-9 | L. Barker 18 | J. McCarthy 3 | J. McCarthy 7 |
| February 6, 2043 | @ #2 Baylor Bears* | L 61-90 | 13-10 | I. Zore 18 | J. McCarthy 3 | F. Zabelle 8 |
| February 10, 2043 | TCU HORNED FROGS* | L 85-99 | 13-11 | F. Zabelle 19 | J. McCarthy 5 | F. Zabelle 9 |
| February 13, 2043 | CINCINNATI BEARCATS (13-12, 4-10, 2-5 Away)* | - | | | | |
| February 17, 2043 | @ Kansas State Wildcats (11-14, 6-8, 5-8 Home)* | - | | | | |
| February 22, 2043 | @ Oklahoma State Cowboys (15-10, 5-9, 11-4 Home)* | - | | | | |
| February 24, 2043 | ARIZONA WILDCATS (5-18, 2-12, 0-11 Away)* | - | | | | |
| March 1, 2043 | @ Arizona State Sun Devils (15-9, 8-6, 10-4 Home)* | - | | | | |
| March 3, 2043 | BAYLOR BEARS (23-3, 12-2, 7-1 Away)* | - | | | | |
