| November 16, 2042 | SAINT JOSEPH'S HAWKS | W 84-65 | 1-0 | H. Chaney 18 | J. Swift 5 | H. Chaney 11 |
| November 19, 2042 | @ #10 Maryland Terrapins | L 67-83 | 1-1 | J. Swift 15 | R. Ouellette 4 | C. Linn 7 |
| November 21, 2042 | WYOMING COWBOYS WSSN Classic | W 71-49 | 2-1 | H. Chaney 21 | R. Ouellette 9 | C. Linn 12 |
| November 22, 2042 | MEMPHIS TIGERS WSSN Classic | W 72-59 | 3-1 | J. Swift 13 | R. Ouellette 5 | D. Henderson 12 |
| November 23, 2042 | MIAMI (FL) HURRICANES WSSN Classic | W 69-60 | 4-1 | C. Linn 16 | R. Ouellette 3 | C. Linn 11 |
| November 26, 2042 | @ Auburn Tigers | W 83-70 | 5-1 | R. Ouellette 20 | R. Ouellette 5 | C. Linn 12 |
| November 30, 2042 | #15 HOUSTON COUGARS | W 88-67 | 6-1 | H. Chaney 21 | R. Ouellette 11 | K. Snow 9 |
| December 3, 2042 | @ Indiana Hoosiers | W 104-97 | 7-1 | R. Ouellette 32 | R. Ouellette 5 | C. Linn 11 |
| December 7, 2042 | EVANSVILLE PURPLE ACES | L 71-81 | 7-2 | K. Snow 20 | R. Ouellette 6 | H. Chaney 8 |
| December 13, 2042 | @ Nebraska Cornhuskers | W 84-75 | 8-2 | D. Henderson 20 | R. Ouellette 7 | C. Linn 11 |
| December 21, 2042 | COLORADO STATE RAMS | W 81-49 | 9-2 | J. Swift 25 | H. Chaney 5 | K. Snow 12 |
| December 26, 2042 | PROVIDENCE FRIARS (4-5, 0-0, 1-2 Away)* | - | | | | |
| December 28, 2042 | @ DePaul Blue Demons (3-7, 0-0, 2-5 Home)* | - | | | | |
| December 30, 2042 | @ Xavier Musketeers (8-2, 0-0, 6-0 Home)* | - | | | | |
| January 2, 2043 | BUTLER BULLDOGS (6-4, 0-0, 1-2 Away)* | - | | | | |
| January 6, 2043 | @ Seton Hall Pirates (8-1, 0-0, 8-0 Home)* | - | | | | |
| January 9, 2043 | @ Marquette Golden Eagles (5-4, 0-0, 4-2 Home)* | - | | | | |
| January 13, 2043 | ST. JOHN'S RED STORM (6-5, 0-0, 0-3 Away)* | - | | | | |
| January 16, 2043 | GEORGETOWN HOYAS (2-8, 0-0, 0-6 Away)* | - | | | | |
| January 18, 2043 | @ Villanova Wildcats (5-4, 0-0, 4-2 Home)* | - | | | | |
| January 20, 2043 | @ Connecticut Huskies (7-4, 0-0, 4-1 Home)* | - | | | | |
| January 25, 2043 | MARQUETTE GOLDEN EAGLES (5-4, 0-0, 1-1 Away)* | - | | | | |
| February 3, 2043 | @ Providence Friars (4-5, 0-0, 3-2 Home)* | - | | | | |
| February 6, 2043 | @ Butler Bulldogs (6-4, 0-0, 4-1 Home)* | - | | | | |
| February 10, 2043 | XAVIER MUSKETEERS (8-2, 0-0, 1-1 Away)* | - | | | | |
| February 13, 2043 | DEPAUL BLUE DEMONS (3-7, 0-0, 0-1 Away)* | - | | | | |
| February 15, 2043 | SETON HALL PIRATES (8-1, 0-0, 0-1 Away)* | - | | | | |
| February 22, 2043 | @ St. John's Red Storm (6-5, 0-0, 4-1 Home)* | - | | | | |
| February 24, 2043 | @ Georgetown Hoyas (2-8, 0-0, 1-1 Home)* | - | | | | |
| March 1, 2043 | CONNECTICUT HUSKIES (7-4, 0-0, 1-2 Away)* | - | | | | |
| March 3, 2043 | VILLANOVA WILDCATS (5-4, 0-0, 1-1 Away)* | - | | | | |
