| November 16, 2042 | SAINT JOSEPH'S HAWKS | W 84-65 | 1-0 | H. Chaney 18 | J. Swift 5 | H. Chaney 11 |
| November 19, 2042 | @ #10 Maryland Terrapins | L 67-83 | 1-1 | J. Swift 15 | R. Ouellette 4 | C. Linn 7 |
| November 21, 2042 | WYOMING COWBOYS WSSN Classic | W 71-49 | 2-1 | H. Chaney 21 | R. Ouellette 9 | C. Linn 12 |
| November 22, 2042 | MEMPHIS TIGERS WSSN Classic | W 72-59 | 3-1 | J. Swift 13 | R. Ouellette 5 | D. Henderson 12 |
| November 23, 2042 | MIAMI (FL) HURRICANES WSSN Classic | W 69-60 | 4-1 | C. Linn 16 | R. Ouellette 3 | C. Linn 11 |
| November 26, 2042 | @ Auburn Tigers | W 83-70 | 5-1 | R. Ouellette 20 | R. Ouellette 5 | C. Linn 12 |
| November 30, 2042 | #15 HOUSTON COUGARS | W 88-67 | 6-1 | H. Chaney 21 | R. Ouellette 11 | K. Snow 9 |
| December 3, 2042 | @ Indiana Hoosiers | W 104-97 | 7-1 | R. Ouellette 32 | R. Ouellette 5 | C. Linn 11 |
| December 7, 2042 | EVANSVILLE PURPLE ACES | L 71-81 | 7-2 | K. Snow 20 | R. Ouellette 6 | H. Chaney 8 |
| December 13, 2042 | @ Nebraska Cornhuskers | W 84-75 | 8-2 | D. Henderson 20 | R. Ouellette 7 | C. Linn 11 |
| December 21, 2042 | COLORADO STATE RAMS | W 81-49 | 9-2 | J. Swift 25 | H. Chaney 5 | K. Snow 12 |
| December 26, 2042 | PROVIDENCE FRIARS* | L 77-86 | 9-3 | H. Chaney 23 | R. Ouellette 9 | K. Snow 12 |
| December 28, 2042 | @ DePaul Blue Demons* | L 78-85 | 9-4 | C. Linn 20 | J. Swift 4 | K. Snow 11 |
| December 30, 2042 | @ #25 Xavier Musketeers* | W 72-65 | 10-4 | H. Chaney 22 | R. Ouellette 7 | H. Chaney 10 |
| January 2, 2043 | #20 BUTLER BULLDOGS* | L 83-86 OT | 10-5 | C. Linn 17 | R. Ouellette 6 | C. Linn 11 |
| January 6, 2043 | @ #25 Seton Hall Pirates* | L 69-83 | 10-6 | H. Chaney 20 | R. Ouellette 9 | C. Linn 14 |
| January 9, 2043 | @ Marquette Golden Eagles* | W 70-63 | 11-6 | J. Swift 17 | R. Ouellette 8 | J. Swift 10 |
| January 13, 2043 | ST. JOHN'S RED STORM* | W 82-58 | 12-6 | J. Swift 18 | H. Chaney 8 | D. Henderson 10 |
| January 16, 2043 | GEORGETOWN HOYAS* | W 82-59 | 13-6 | J. Swift 24 | R. Ouellette 9 | K. Snow 11 |
| January 18, 2043 | @ Villanova Wildcats* | W 79-76 | 14-6 | K. Snow 19 | R. Ouellette 4 | K. Snow 10 |
| January 20, 2043 | @ Connecticut Huskies* | W 84-74 | 15-6 | R. Ouellette 17 | R. Ouellette 7 | C. Linn 8 |
| January 25, 2043 | MARQUETTE GOLDEN EAGLES* | L 77-89 | 15-7 | J. Swift 29 | R. Ouellette 4 | H. Chaney 9 |
| February 3, 2043 | @ Providence Friars* | W 90-83 | 16-7 | R. Ouellette 21 | R. Ouellette 5 | K. Snow 13 |
| February 6, 2043 | @ #10 Butler Bulldogs* | L 71-85 | 16-8 | J. Swift 20 | R. Ouellette 3 | C. Linn 8 |
| February 10, 2043 | XAVIER MUSKETEERS* | W 100-94 | 17-8 | H. Chaney 33 | R. Ouellette 7 | H. Chaney 13 |
| February 13, 2043 | DEPAUL BLUE DEMONS (10-13, 7-6, 3-5 Away)* | - | | | | |
| February 15, 2043 | SETON HALL PIRATES (17-6, 9-5, 2-5 Away)* | - | | | | |
| February 22, 2043 | @ St. John's Red Storm (9-17, 3-12, 7-6 Home)* | - | | | | |
| February 24, 2043 | @ Georgetown Hoyas (8-17, 6-9, 4-5 Home)* | - | | | | |
| March 1, 2043 | CONNECTICUT HUSKIES (16-10, 9-6, 4-6 Away)* | - | | | | |
| March 3, 2043 | VILLANOVA WILDCATS (9-15, 4-11, 1-8 Away)* | - | | | | |
