| November 18, 2042 | LONGWOOD LANCERS | W 82-74 | 1-0 | L. Drury 16 | R. Bowen 4 | N. Ellis 6 |
| November 21, 2042 | @ Nevada Wolfpack Charleston Classic | W 78-75 | 2-0 | M. Williams 15 | R. Bowen 4 | N. Ellis 13 |
| November 22, 2042 | PITTSBURGH PANTHERS Charleston Classic | L 71-78 | 2-1 | A. Fisher 19 | L. Drury 8 | J. Braxton 6 |
| November 26, 2042 | @ Duke Blue Devils | L 57-81 | 2-2 | N. Ellis 13 | A. Fisher 5 | L. Drury 6 |
| November 30, 2042 | @ South Florida Bulls | L 80-88 | 2-3 | A. Acani 16 | N. Ellis 4 | A. Acani 9 |
| December 2, 2042 | @ Miami (OH) Red Hawks | W 72-71 | 3-3 | R. Bowen 18 | R. Bowen 6 | M. Williams 8 |
| December 7, 2042 | @ #4 Stanford Cardinal | L 48-72 | 3-4 | N. Ellis 9 | R. Bowen 3 | A. Acani 8 |
| December 13, 2042 | @ Eastern Michigan Eagles | W 92-83 | 4-4 | L. Drury 29 | R. Bowen 5 | N. Ellis 14 |
| December 15, 2042 | FLORIDA GULF COAST EAGLES | W 72-69 | 5-4 | L. Drury 13 | L. Drury 6 | L. Drury 7 |
| December 21, 2042 | @ Coastal Carolina Chanticleers | L 73-87 | 5-5 | N. Ellis 19 | R. Bowen 3 | A. Acani 10 |
| December 26, 2042 | @ Cleveland State Vikings* | W 93-86 | 6-5 | M. Williams 14 | R. Bowen 4 | M. Williams 7 |
| December 30, 2042 | YOUNGSTOWN STATE PENGUINS* | W 67-58 | 7-5 | R. Bowen 20 | R. Bowen 4 | M. Williams 8 |
| January 2, 2043 | @ Milwaukee Panthers* | L 77-82 | 7-6 | M. Williams 18 | R. Bowen 8 | L. Drury 10 |
| January 4, 2043 | GREEN BAY PHOENIX* | L 57-69 | 7-7 | R. Bowen 11 | L. Drury 4 | A. Acani 7 |
| January 6, 2043 | IU INDY JAGUARS* | W 93-73 | 8-7 | A. Fisher 21 | R. Bowen 5 | A. Acani 9 |
| January 11, 2043 | @ Oakland Golden Grizzlies* | L 61-66 | 8-8 | J. Williamson 15 | L. Drury 4 | J. Williamson 7 |
| January 13, 2043 | @ Purdue Fort Wayne Mastodons* | W 97-91 | 9-8 | A. Fisher 21 | R. Bowen 11 | N. Ellis 5 |
| January 18, 2043 | NORTHERN KENTUCKY NORSE* | W 94-79 | 10-8 | N. Ellis 19 | W. Villalobos 5 | N. Ellis 10 |
| January 23, 2043 | @ Green Bay Phoenix* | W 87-68 | 11-8 | R. Bowen 25 | R. Bowen 6 | N. Ellis 8 |
| January 27, 2043 | WRIGHT STATE RAIDERS* | W 78-73 | 12-8 | N. Ellis 15 | R. Bowen 4 | N. Ellis 6 |
| January 30, 2043 | ROBERT MORRIS COLONIALS* | L 72-73 | 12-9 | R. Bowen 24 | R. Bowen 2 | A. Acani 8 |
| February 1, 2043 | @ IU Indy Jaguars* | W 74-68 | 13-9 | R. Bowen 16 | R. Bowen 5 | N. Ellis 7 |
| February 3, 2043 | @ Youngstown State Penguins* | L 46-77 | 13-10 | A. Acani 10 | L. Drury 3 | A. Acani 9 |
| February 8, 2043 | PURDUE FORT WAYNE MASTODONS* | W 84-65 | 14-10 | L. Drury 22 | R. Bowen 8 | M. Williams 8 |
| February 10, 2043 | OAKLAND GOLDEN GRIZZLIES* | W 71-39 | 15-10 | L. Drury 16 | R. Bowen 11 | L. Drury 7 |
| February 15, 2043 | @ Wright State Raiders (7-16, 5-9, 5-4 Home)* | - | | | | |
| February 17, 2043 | @ Robert Morris Colonials (13-9, 8-5, 4-6 Home)* | - | | | | |
| February 22, 2043 | MILWAUKEE PANTHERS (14-9, 10-4, 7-6 Away)* | - | | | | |
| February 24, 2043 | CLEVELAND STATE VIKINGS (13-12, 5-10, 7-7 Away)* | - | | | | |
| March 3, 2043 | @ Northern Kentucky Norse (6-17, 3-11, 4-4 Home)* | - | | | | |
