| November 16, 2042 | TEXAS A&M AGGIES | W 78-69 | 1-0 | K. Minor 14 | D. Miller 4 | J. York 8 |
| November 18, 2042 | NORFOLK STATE SPARTANS Allstate Maui Invitational | L 70-72 | 1-1 | J. Wolfe 12 | K. Minor 3 | J. York 8 |
| November 23, 2042 | NEW MEXICO STATE AGGIES | W 87-72 | 2-1 | K. Minor 19 | J. Wolfe 5 | S. Coyne 9 |
| November 26, 2042 | DETROIT MERCY TITANS | W 81-57 | 3-1 | S. Coyne 20 | K. Minor 5 | D. Miller 7 |
| December 1, 2042 | @ Arizona Wildcats | W 80-79 | 4-1 | D. Miller 16 | C. Yearwood 4 | J. York 7 |
| December 10, 2042 | UNLV RUNNIN' REBELS | W 86-74 | 5-1 | C. Yearwood 21 | K. Minor 5 | S. Coyne 9 |
| December 13, 2042 | @ Michigan Wolverines | L 82-84 | 5-2 | C. Yearwood 21 | K. Minor 6 | C. Yearwood 7 |
| December 16, 2042 | TENNESSEE VOLUNTEERS | L 76-84 | 5-3 | C. Yearwood 17 | K. Minor 6 | J. York 8 |
| December 23, 2042 | @ Florida Gators | L 105-107 OT | 5-4 | C. Yearwood 21 | K. Minor 4 | D. Miller 8 |
| December 26, 2042 | @ #8 Stanford Cardinal* | L 65-83 | 5-5 | C. Yearwood 18 | K. Minor 8 | S. Coyne 8 |
| December 28, 2042 | #12 LOUISVILLE CARDINALS* | W 89-84 OT | 6-5 | C. Yearwood 20 | K. Minor 4 | J. Wolfe 10 |
| January 2, 2043 | @ California Golden Bears* | W 85-57 | 7-5 | C. Yearwood 22 | D. Miller 5 | D. Miller 9 |
| January 4, 2043 | PITTSBURGH PANTHERS* | L 70-74 | 7-6 | K. Minor 13 | K. Minor 5 | J. Wolfe 11 |
| January 9, 2043 | @ Virginia Cavaliers* | L 67-90 | 7-7 | C. Yearwood 19 | D. Miller 5 | J. Wolfe 10 |
| January 11, 2043 | #24 FLORIDA STATE SEMINOLES* | W 85-81 | 8-7 | K. Minor 19 | K. Minor 4 | D. Miller 6 |
| January 16, 2043 | #2 NORTH CAROLINA TAR HEELS* | L 57-83 | 8-8 | J. York 11 | Z. Wells 4 | D. Miller 8 |
| January 18, 2043 | GEORGIA TECH YELLOW JACKETS* | W 65-58 | 9-8 | C. Yearwood 21 | Z. Wells 5 | J. Wolfe 8 |
| January 23, 2043 | @ Wake Forest Demon Deacons* | W 74-66 | 10-8 | K. Minor 17 | J. Walden 5 | J. Wolfe 7 |
| January 25, 2043 | VIRGINIA TECH HOKIES* | W 87-63 | 11-8 | C. Yearwood 14 | K. Minor 6 | J. Wolfe 10 |
| January 30, 2043 | @ SMU Mustangs* | W 77-63 | 12-8 | J. Walden 14 | D. Miller 3 | J. York 8 |
| February 1, 2043 | @ Boston College Eagles* | L 72-91 | 12-9 | D. Miller 14 | E. Lennon 4 | D. Miller 8 |
| February 6, 2043 | @ Syracuse Orange* | W 77-62 | 13-9 | D. Miller 13 | K. Minor 3 | D. Miller 8 |
| February 8, 2043 | @ #11 Notre Dame Fighting Irish* | L 67-98 | 13-10 | C. Yearwood 11 | J. Walden 4 | J. York 9 |
| February 13, 2043 | MIAMI (FL) HURRICANES (16-9, 7-7, 2-7 Away)* | - | | | | |
| February 15, 2043 | CLEMSON TIGERS (7-16, 5-9, 3-8 Away)* | - | | | | |
| February 20, 2043 | NC STATE WOLFPACK (15-8, 9-5, 3-5 Away)* | - | | | | |
| February 22, 2043 | @ North Carolina Tar Heels (24-1, 14-0, 12-0 Home)* | - | | | | |
| February 27, 2043 | STANFORD CARDINAL (20-6, 9-5, 5-4 Away)* | - | | | | |
| March 1, 2043 | @ Miami (FL) Hurricanes (16-9, 7-7, 12-1 Home)* | - | | | | |
