| November 14, 2042 | @ #16 West Virginia Mountaineers | L 50-84 | 0-1 | W. Burch 8 | W. Burch 4 | L. Conley 4 |
| November 17, 2042 | LIPSCOMB BISONS | W 80-59 | 1-1 | J. Kelleher 20 | W. Burch 7 | R. Barber 11 |
| November 22, 2042 | @ SE Louisiana Lions | L 78-96 | 1-2 | T. Hahn 16 | W. Burch 9 | R. Barber 10 |
| November 24, 2042 | @ UT Rio Grande Valley Vaqueros | W 73-71 | 2-2 | L. Conley 14 | W. Burch 3 | T. Hahn 9 |
| November 29, 2042 | @ Valparaiso Crusaders | L 61-80 | 2-3 | J. Kelleher 20 | W. Burch 9 | R. Barber 7 |
| December 3, 2042 | @ South Dakota State Jackrabbits | W 87-85 | 3-3 | L. Conley 26 | W. Burch 6 | J. Kelleher 10 |
| December 6, 2042 | BELLARMINE KNIGHTS | W 87-55 | 4-3 | J. Kelleher 17 | W. Burch 7 | J. Kelleher 10 |
| December 9, 2042 | @ Syracuse Orange Cayman Islands Classic | W 83-65 | 5-3 | J. Kelleher 16 | W. Burch 8 | R. Barber 10 |
| December 10, 2042 | INDIANA HOOSIERS Cayman Islands Classic | L 72-93 | 5-4 | L. Conley 14 | W. Burch 3 | R. Barber 10 |
| December 13, 2042 | @ Robert Morris Colonials | L 77-80 | 5-5 | J. Kelleher 17 | W. Burch 8 | W. Burch 6 |
| December 21, 2042 | @ Marquette Golden Eagles | L 53-63 | 5-6 | J. Kelleher 21 | W. Burch 7 | J. Kelleher 9 |
| December 23, 2042 | @ New Mexico Lobos | L 80-100 | 5-7 | W. Burch 23 | T. Hahn 5 | R. Barber 16 |
| January 2, 2043 | LA SALLE EXPLORERS* | W 76-71 | 6-7 | L. Conley 12 | W. Burch 7 | R. Barber 6 |
| January 5, 2043 | GEORGE MASON PATRIOTS* | L 77-83 | 6-8 | L. Conley 30 | W. Burch 8 | J. Kelleher 9 |
| January 7, 2043 | @ Richmond Spiders* | W 82-67 | 7-8 | T. Hahn 19 | W. Burch 6 | R. Barber 8 |
| January 12, 2043 | @ Fordham Rams* | W 78-68 | 8-8 | R. Barber 16 | W. Burch 4 | R. Barber 12 |
| January 16, 2043 | GEORGE WASHINGTON COLONIALS* | L 63-83 | 8-9 | L. Conley 23 | W. Burch 4 | J. Kelleher 10 |
| January 19, 2043 | @ Saint Louis Billikens* | L 80-88 | 8-10 | L. Conley 17 | W. Burch 9 | R. Barber 12 |
| January 21, 2043 | @ Rhode Island Rams* | L 82-95 | 8-11 | J. Kelleher 18 | W. Burch 7 | R. Barber 11 |
| January 23, 2043 | DAVIDSON WILDCATS* | W 84-61 | 9-11 | J. Kelleher 20 | W. Burch 7 | R. Barber 14 |
| January 28, 2043 | SAINT JOSEPH'S HAWKS* | W 87-69 | 10-11 | R. Barber 19 | W. Burch 7 | R. Barber 9 |
| January 30, 2043 | @ Dayton Flyers* | W 90-80 | 11-11 | R. Barber 25 | W. Burch 5 | R. Barber 10 |
| February 4, 2043 | UMASS MINUTEMEN* | W 83-71 | 12-11 | J. Kelleher 25 | W. Burch 9 | R. Barber 7 |
| February 9, 2043 | #6 VCU RAMS* | L 88-99 | 12-12 | L. Conley 28 | W. Burch 8 | T. Hahn 10 |
| February 13, 2043 | @ Saint Joseph's Hawks (11-12, 6-5, 5-4 Home)* | - | | | | |
| February 16, 2043 | @ St. Bonaventure Bonnies (10-13, 5-7, 8-5 Home)* | - | | | | |
| February 18, 2043 | @ Davidson Wildcats (7-17, 3-10, 5-8 Home)* | - | | | | |
| February 23, 2043 | RICHMOND SPIDERS (4-19, 1-11, 0-9 Away)* | - | | | | |
| February 25, 2043 | LOYOLA CHICAGO RAMBLERS (12-12, 4-9, 3-6 Away)* | - | | | | |
| February 27, 2043 | @ UMass Minutemen (12-11, 7-5, 10-3 Home)* | - | | | | |
