| November 14, 2042 | @ #16 West Virginia Mountaineers | L 50-84 | 0-1 | W. Burch 8 | W. Burch 4 | L. Conley 4 |
| November 17, 2042 | LIPSCOMB BISONS | W 80-59 | 1-1 | J. Kelleher 20 | W. Burch 7 | R. Barber 11 |
| November 22, 2042 | @ SE Louisiana Lions | L 78-96 | 1-2 | T. Hahn 16 | W. Burch 9 | R. Barber 10 |
| November 24, 2042 | @ UT Rio Grande Valley Vaqueros | W 73-71 | 2-2 | L. Conley 14 | W. Burch 3 | T. Hahn 9 |
| November 29, 2042 | @ Valparaiso Crusaders | L 61-80 | 2-3 | J. Kelleher 20 | W. Burch 9 | R. Barber 7 |
| December 3, 2042 | @ South Dakota State Jackrabbits | W 87-85 | 3-3 | L. Conley 26 | W. Burch 6 | J. Kelleher 10 |
| December 6, 2042 | BELLARMINE KNIGHTS | W 87-55 | 4-3 | J. Kelleher 17 | W. Burch 7 | J. Kelleher 10 |
| December 9, 2042 | @ Syracuse Orange Cayman Islands Classic | W 83-65 | 5-3 | J. Kelleher 16 | W. Burch 8 | R. Barber 10 |
| December 10, 2042 | INDIANA HOOSIERS Cayman Islands Classic | L 72-93 | 5-4 | L. Conley 14 | W. Burch 3 | R. Barber 10 |
| December 13, 2042 | @ Robert Morris Colonials | L 77-80 | 5-5 | J. Kelleher 17 | W. Burch 8 | W. Burch 6 |
| December 21, 2042 | @ Marquette Golden Eagles | L 53-63 | 5-6 | J. Kelleher 21 | W. Burch 7 | J. Kelleher 9 |
| December 23, 2042 | @ New Mexico Lobos | L 80-100 | 5-7 | W. Burch 23 | T. Hahn 5 | R. Barber 16 |
| January 2, 2043 | LA SALLE EXPLORERS (8-2, 0-0, 2-1 Away)* | - | | | | |
| January 5, 2043 | GEORGE MASON PATRIOTS (7-4, 0-0, 2-1 Away)* | - | | | | |
| January 7, 2043 | @ Richmond Spiders (2-8, 0-0, 2-4 Home)* | - | | | | |
| January 12, 2043 | @ Fordham Rams (6-4, 0-0, 3-2 Home)* | - | | | | |
| January 16, 2043 | GEORGE WASHINGTON COLONIALS (5-6, 0-0, 2-3 Away)* | - | | | | |
| January 19, 2043 | @ Saint Louis Billikens (6-4, 0-0, 4-1 Home)* | - | | | | |
| January 21, 2043 | @ Rhode Island Rams (7-3, 0-0, 4-0 Home)* | - | | | | |
| January 23, 2043 | DAVIDSON WILDCATS (2-7, 0-0, 1-2 Away)* | - | | | | |
| January 28, 2043 | SAINT JOSEPH'S HAWKS (4-7, 0-0, 2-4 Away)* | - | | | | |
| January 30, 2043 | @ Dayton Flyers (4-6, 0-0, 4-1 Home)* | - | | | | |
| February 4, 2043 | UMASS MINUTEMEN (4-6, 0-0, 1-3 Away)* | - | | | | |
| February 9, 2043 | VCU RAMS (8-3, 0-0, 2-2 Away)* | - | | | | |
| February 13, 2043 | @ Saint Joseph's Hawks (4-7, 0-0, 1-2 Home)* | - | | | | |
| February 16, 2043 | @ St. Bonaventure Bonnies (4-6, 0-0, 4-2 Home)* | - | | | | |
| February 18, 2043 | @ Davidson Wildcats (2-7, 0-0, 1-4 Home)* | - | | | | |
| February 23, 2043 | RICHMOND SPIDERS (2-8, 0-0, 0-3 Away)* | - | | | | |
| February 25, 2043 | LOYOLA CHICAGO RAMBLERS (7-3, 0-0, 2-1 Away)* | - | | | | |
| February 27, 2043 | @ UMass Minutemen (4-6, 0-0, 3-2 Home)* | - | | | | |
