| November 16, 2042 | @ Monmouth Hawks | L 91-97 | 0-1 | A. Houston 15 | A. Houston 4 | S. Holguin 8 |
| November 18, 2042 | TENNESSEE TECH GOLDEN EAGLES | W 65-57 | 1-1 | C. Gilbert 13 | B. Dawson 4 | C. Gilbert 8 |
| November 23, 2042 | @ Butler Bulldogs | L 67-84 | 1-2 | D. Hedrick 15 | A. Minor 5 | C. Gilbert 7 |
| November 26, 2042 | @ Princeton Tigers | W 84-76 | 2-2 | S. Holguin 26 | B. Phillips 3 | S. Holguin 9 |
| November 29, 2042 | @ VCU Rams | L 60-82 | 2-3 | B. Phillips 11 | A. Houston 5 | S. Holguin 8 |
| December 1, 2042 | LAMAR CARDINALS | W 73-65 | 3-3 | D. Hedrick 17 | A. Houston 6 | C. Gilbert 6 |
| December 6, 2042 | MOREHEAD STATE EAGLES | W 75-65 | 4-3 | A. Houston 16 | B. Phillips 5 | D. Hedrick 6 |
| December 13, 2042 | UNC WILMINGTON SEAHAWKS | W 85-81 | 5-3 | B. Phillips 23 | A. Houston 6 | S. Holguin 12 |
| December 16, 2042 | @ #16 Maryland Terrapins Diamond Head Classic | L 66-79 | 5-4 | S. Holguin 23 | D. Hedrick 3 | S. Holguin 13 |
| December 19, 2042 | @ #18 Oklahoma State Cowboys | L 57-64 | 5-5 | B. Phillips 12 | A. Houston 7 | C. Gilbert 10 |
| December 26, 2042 | FDU KNIGHTS (7-5, 3-5 Away) | - | | | | |
| January 2, 2043 | @ Wichita State Shockers (10-2, 0-0, 6-0 Home)* | - | | | | |
| January 9, 2043 | @ South Florida Bulls (9-2, 0-0, 8-1 Home)* | - | | | | |
| January 12, 2043 | UAB BLAZERS (3-8, 0-0, 0-3 Away)* | - | | | | |
| January 14, 2043 | @ UTSA Roadrunners (4-7, 0-0, 3-3 Home)* | - | | | | |
| January 16, 2043 | @ Charlotte 49ers (8-5, 0-0, 4-0 Home)* | - | | | | |
| January 19, 2043 | NORTH TEXAS MEAN GREEN (4-6, 0-0, 1-3 Away)* | - | | | | |
| January 23, 2043 | UTSA ROADRUNNERS (4-7, 0-0, 0-3 Away)* | - | | | | |
| January 26, 2043 | @ Temple Owls (4-6, 0-0, 4-4 Home)* | - | | | | |
| January 28, 2043 | @ North Texas Mean Green (4-6, 0-0, 3-2 Home)* | - | | | | |
| January 30, 2043 | TULSA GOLDEN HURRICANES (5-6, 0-0, 0-3 Away)* | - | | | | |
| February 2, 2043 | @ Tulane Green Wave (7-3, 0-0, 5-0 Home)* | - | | | | |
| February 6, 2043 | @ UAB Blazers (3-8, 0-0, 2-4 Home)* | - | | | | |
| February 9, 2043 | FLORIDA ATLANTIC OWLS (5-4, 0-0, 2-1 Away)* | - | | | | |
| February 13, 2043 | RICE OWLS (3-7, 0-0, 0-3 Away)* | - | | | | |
| February 16, 2043 | @ Memphis Tigers (4-8, 0-0, 3-3 Home)* | - | | | | |
| February 20, 2043 | WICHITA STATE SHOCKERS (10-2, 0-0, 2-1 Away)* | - | | | | |
| February 27, 2043 | SOUTH FLORIDA BULLS (9-2, 0-0, 0-0 Away)* | - | | | | |
| March 2, 2043 | CHARLOTTE 49ERS (8-5, 0-0, 1-4 Away)* | - | | | | |
