| November 16, 2042 | WISCONSIN BADGERS | W 68-48 | 1-0 | J. Worrell 24 | D. White 4 | J. Worrell 12 |
| November 19, 2042 | KENT STATE GOLDEN FLASHES | W 70-50 | 2-0 | T. Bowling 12 | D. White 6 | M. Cummins 11 |
| November 23, 2042 | WOFFORD TERRIERS | W 75-66 | 3-0 | J. Worrell 14 | D. White 4 | J. Worrell 11 |
| November 26, 2042 | @ Arizona State Sun Devils | L 53-73 | 3-1 | T. Bowling 14 | E. Shepherd 4 | J. Worrell 12 |
| November 30, 2042 | COLORADO BUFFALOES | W 81-73 | 4-1 | M. Cummins 26 | D. White 3 | E. Shepherd 7 |
| December 3, 2042 | PENN STATE NITTANY LIONS | W 72-64 | 5-1 | T. Bowling 15 | E. Shepherd 3 | J. Worrell 14 |
| December 7, 2042 | WYOMING COWBOYS | W 79-45 | 6-1 | J. Worrell 24 | D. White 9 | J. Worrell 12 |
| December 13, 2042 | @ Florida Gators | L 79-86 OT | 6-2 | E. Shepherd 19 | T. Bowling 5 | M. Cummins 10 |
| December 21, 2042 | UMASS MINUTEMEN | W 89-76 | 7-2 | M. Cummins 22 | D. White 5 | J. Worrell 13 |
| December 26, 2042 | SYRACUSE ORANGE* | W 72-59 | 8-2 | T. Bowling 17 | D. White 3 | J. Worrell 6 |
| December 28, 2042 | #5 NORTH CAROLINA TAR HEELS* | L 70-98 | 8-3 | M. Cummins 15 | D. White 4 | M. Cummins 6 |
| January 2, 2043 | @ SMU Mustangs* | L 77-86 | 8-4 | M. Cummins 19 | D. White 7 | M. Cummins 13 |
| January 4, 2043 | @ Wake Forest Demon Deacons* | W 80-70 | 9-4 | E. Shepherd 19 | D. White 5 | J. Worrell 8 |
| January 9, 2043 | #14 NOTRE DAME FIGHTING IRISH* | L 61-76 | 9-5 | E. Shepherd 21 | D. White 7 | M. Cummins 11 |
| January 11, 2043 | @ Duke Blue Devils* | L 81-85 | 9-6 | M. Cummins 16 | D. White 6 | J. Worrell 14 |
| January 16, 2043 | @ Clemson Tigers* | L 71-79 | 9-7 | M. Cummins 15 | M. Callier 4 | M. Cummins 8 |
| January 18, 2043 | CALIFORNIA GOLDEN BEARS* | W 74-56 | 10-7 | J. Worrell 14 | D. White 6 | J. Worrell 12 |
| January 23, 2043 | @ Georgia Tech Yellow Jackets* | L 75-84 | 10-8 | J. Worrell 15 | T. Bowling 3 | J. Worrell 13 |
| January 25, 2043 | #22 LOUISVILLE CARDINALS* | W 76-56 | 11-8 | M. Callier 13 | D. White 6 | E. Shepherd 9 |
| January 30, 2043 | VIRGINIA TECH HOKIES* | W 71-48 | 12-8 | J. Worrell 15 | D. White 5 | J. Worrell 16 |
| February 1, 2043 | @ Virginia Cavaliers* | W 74-70 | 13-8 | E. Shepherd 16 | T. Bowling 4 | M. Cummins 11 |
| February 6, 2043 | @ #9 Stanford Cardinal* | W 89-75 | 14-8 | E. Shepherd 25 | D. White 5 | E. Shepherd 10 |
| February 8, 2043 | @ NC State Wolfpack* | L 74-83 | 14-9 | M. Cummins 17 | D. White 6 | M. Cummins 7 |
| February 13, 2043 | PITTSBURGH PANTHERS* | W 67-53 | 15-9 | M. Cummins 14 | D. White 5 | M. Cummins 17 |
| February 15, 2043 | BOSTON COLLEGE EAGLES* | W 77-74 | 16-9 | J. Worrell 24 | D. White 9 | J. Worrell 12 |
| February 20, 2043 | MIAMI (FL) HURRICANES* | W 82-61 | 17-9 | E. Shepherd 13 | D. White 6 | L. Kinzer 7 |
| February 22, 2043 | @ Syracuse Orange* | W 74-64 | 18-9 | E. Shepherd 14 | D. White 4 | E. Shepherd 8 |
| February 27, 2043 | @ #1 North Carolina Tar Heels* | L 77-92 | 18-10 | L. Kinzer 24 | D. White 3 | L. Kinzer 7 |
| March 1, 2043 | WAKE FOREST DEMON DEACONS* | W 77-47 | 19-10 | J. Worrell 20 | D. White 6 | M. Cummins 12 |
| March 9, 2043 | GEORGIA TECH YELLOW JACKETS ACC Tournament | W 85-67 | 20-10 | J. Worrell 17 | L. Kinzer 5 | J. Worrell 9 |
| March 10, 2043 | @ SMU Mustangs ACC Tournament | W 81-64 | 21-10 | E. Shepherd 22 | D. White 8 | M. Cummins 10 |
| March 11, 2043 | @ #1 North Carolina Tar Heels ACC Tournament | L 63-81 | 21-11 | J. Worrell 15 | D. Sanchez 3 | J. Worrell 10 |
| March 17, 2043 | @ Penn State Nittany Lions NCAA Tournament | W 72-61 | 22-11 | J. Bell 14 | D. White 7 | J. Worrell 13 |
| March 19, 2043 | @ #10 Notre Dame Fighting Irish NCAA Tournament | L 76-81 | 22-12 | E. Shepherd 20 | D. White 8 | M. Cummins 10 |
