| November 16, 2042 | PITTSBURGH PANTHERS | W 79-74 | 1-0 | L. Hayes 21 | M. Atkinson 3 | M. Doliboa 10 |
| November 18, 2042 | MONTANA STATE BOBCATS | L 58-67 | 1-1 | A. Nolan 17 | M. Atkinson 3 | B. Colbert 13 |
| November 21, 2042 | @ #16 Saint Mary's Gaels | L 58-71 | 1-2 | M. Atkinson 19 | N. Tuttle 3 | N. Tuttle 7 |
| November 25, 2042 | WESTERN KENTUCKY HILLTOPPERS ESPN Events Invitational | L 64-84 | 1-3 | N. Tuttle 17 | M. Atkinson 3 | N. Tuttle 9 |
| November 30, 2042 | PENN STATE NITTANY LIONS | L 87-111 | 1-4 | A. Nolan 20 | H. Berry 5 | A. Nolan 5 |
| December 1, 2042 | @ #6 West Virginia Mountaineers | L 72-91 | 1-5 | N. Tuttle 20 | M. Atkinson 5 | N. Tuttle 4 |
| December 5, 2042 | LIPSCOMB BISONS | W 80-77 | 2-5 | B. Colbert 20 | M. Atkinson 5 | B. Colbert 8 |
| December 9, 2042 | @ Kentucky Wildcats | L 63-85 | 2-6 | M. Atkinson 18 | M. Atkinson 3 | N. Tuttle 5 |
| December 13, 2042 | @ James Madison Dukes | W 82-80 | 3-6 | N. Tuttle 17 | M. Atkinson 5 | B. Colbert 8 |
| December 16, 2042 | NORTH CAROLINA CENTRAL EAGLES | W 84-73 | 4-6 | N. Tuttle 18 | H. Berry 7 | A. Nolan 9 |
| December 20, 2042 | @ Jacksonville State Gamecocks | W 77-74 | 5-6 | M. Atkinson 19 | M. Atkinson 6 | B. Colbert 8 |
| January 5, 2043 | DAYTON FLYERS* | L 62-77 | 5-7 | M. Atkinson 16 | M. Atkinson 4 | B. Colbert 9 |
| January 7, 2043 | SAINT JOSEPH'S HAWKS* | W 77-60 | 6-7 | M. Atkinson 16 | B. Colbert 4 | A. Nolan 10 |
| January 12, 2043 | #11 VCU RAMS* | L 49-72 | 6-8 | N. Tuttle 14 | M. Atkinson 2 | A. Nolan 6 |
| January 16, 2043 | @ Duquesne Dukes* | W 83-63 | 7-8 | M. Atkinson 27 | B. Colbert 4 | B. Colbert 9 |
| January 19, 2043 | RHODE ISLAND RAMS* | L 74-85 | 7-9 | A. Nolan 16 | H. Berry 4 | B. Colbert 9 |
| January 21, 2043 | @ Davidson Wildcats* | W 74-69 | 8-9 | M. Atkinson 24 | M. Atkinson 5 | B. Colbert 8 |
| January 23, 2043 | @ St. Bonaventure Bonnies* | L 49-66 | 8-10 | A. Nolan 14 | L. Hayes 3 | N. Tuttle 9 |
| January 26, 2043 | @ Saint Joseph's Hawks* | L 79-84 | 8-11 | N. Tuttle 17 | L. Hayes 5 | N. Tuttle 8 |
| January 28, 2043 | FORDHAM RAMS* | L 53-66 | 8-12 | L. Hayes 15 | L. Hayes 3 | A. Nolan 9 |
| February 2, 2043 | @ Saint Louis Billikens* | W 80-67 | 9-12 | B. Colbert 19 | M. Atkinson 8 | B. Colbert 10 |
| February 4, 2043 | @ Loyola Chicago Ramblers* | L 61-88 | 9-13 | L. Hayes 13 | L. Hayes 8 | K. Blanks 8 |
| February 11, 2043 | ST. BONAVENTURE BONNIES* | L 56-78 | 9-14 | B. Colbert 13 | M. Atkinson 5 | B. Colbert 9 |
| February 13, 2043 | DAVIDSON WILDCATS (7-17, 3-10, 2-8 Away)* | - | | | | |
| February 18, 2043 | GEORGE MASON PATRIOTS (15-9, 7-5, 4-5 Away)* | - | | | | |
| February 20, 2043 | @ La Salle Explorers (19-5, 10-3, 13-1 Home)* | - | | | | |
| February 25, 2043 | UMASS MINUTEMEN (12-11, 7-5, 2-7 Away)* | - | | | | |
| March 2, 2043 | @ Fordham Rams (12-12, 6-7, 7-4 Home)* | - | | | | |
| March 4, 2043 | @ Richmond Spiders (4-19, 1-11, 4-9 Home)* | - | | | | |
