| November 14, 2042 | AUSTIN PEAY GOVERNORS | L 80-82 | 0-1 | R. Penn 26 | R. Penn 5 | A. Irving 10 |
| November 17, 2042 | @ VMI Keydets | W 72-66 | 1-1 | M. Stojanovic 14 | R. Penn 3 | L. Purvis 7 |
| November 22, 2042 | MIAMI (OH) RED HAWKS | W 74-73 | 2-1 | R. Penn 19 | L. Purvis 5 | L. Purvis 8 |
| November 24, 2042 | @ Pacific Tigers | L 61-75 | 2-2 | R. Penn 22 | R. Penn 3 | R. Penn 14 |
| November 29, 2042 | @ Tennessee Tech Golden Eagles | L 61-73 | 2-3 | A. Irving 12 | M. Ware 5 | L. Purvis 7 |
| December 1, 2042 | @ New Orleans Privateers | L 54-61 | 2-4 | R. Penn 17 | R. Penn 5 | R. Penn 7 |
| December 7, 2042 | @ #23 Seton Hall Pirates | L 69-86 | 2-5 | W. Boyer 20 | A. Irving 5 | M. Ware 6 |
| December 13, 2042 | @ Stonehill Skyhawks | L 59-75 | 2-6 | R. Penn 12 | R. Penn 3 | A. Irving 9 |
| December 19, 2042 | @ Portland Pilots | L 61-76 | 2-7 | W. Boyer 13 | R. Penn 4 | R. Penn 5 |
| December 22, 2042 | LINDENWOOD LIONS | W 71-67 | 3-7 | M. Stojanovic 14 | R. Penn 5 | L. Purvis 6 |
| December 26, 2042 | GEORGIA STATE PANTHERS | L 66-87 | 3-8 | W. Boyer 19 | W. Boyer 3 | A. Irving 12 |
| January 2, 2043 | LAFAYETTE LEOPARDS* | L 48-79 | 3-9 | R. Penn 15 | R. Penn 2 | A. Irving 10 |
| January 5, 2043 | @ Boston University Terriers* | L 55-74 | 3-10 | M. Stojanovic 14 | R. Penn 3 | A. Irving 5 |
| January 9, 2043 | LOYOLA MARYLAND GREYHOUNDS* | L 73-81 | 3-11 | R. Penn 18 | R. Penn 5 | L. Purvis 10 |
| January 12, 2043 | @ Navy Midshipmen* | W 72-60 | 4-11 | L. Purvis 18 | R. Penn 5 | A. Irving 12 |
| January 16, 2043 | BUCKNELL BISON* | L 63-75 | 4-12 | W. Boyer 19 | R. Penn 6 | L. Purvis 9 |
| January 19, 2043 | @ American Eagles* | L 55-70 | 4-13 | L. Purvis 14 | W. Boyer 5 | A. Irving 10 |
| January 23, 2043 | COLGATE RAIDERS* | L 64-75 | 4-14 | R. Penn 14 | R. Penn 4 | A. Irving 10 |
| January 26, 2043 | LEHIGH MOUNTAIN HAWKS* | W 70-41 | 5-14 | R. Penn 16 | R. Penn 3 | W. Boyer 6 |
| January 30, 2043 | @ Army Black Knights* | W 82-80 OT | 6-14 | W. Boyer 18 | R. Penn 7 | R. Penn 8 |
| February 2, 2043 | @ Lafayette Leopards* | L 62-71 | 6-15 | L. Purvis 15 | A. Irving 8 | M. Stojanovic 9 |
| February 6, 2043 | BOSTON UNIVERSITY TERRIERS* | L 68-92 | 6-16 | R. Penn 15 | R. Penn 6 | W. Boyer 6 |
| February 9, 2043 | @ Loyola Maryland Greyhounds* | W 84-77 | 7-16 | R. Penn 32 | R. Penn 6 | L. Purvis 8 |
| February 13, 2043 | NAVY MIDSHIPMEN (7-16, 5-7, 3-10 Away)* | - | | | | |
| February 16, 2043 | @ Bucknell Bison (14-11, 7-5, 6-3 Home)* | - | | | | |
| February 20, 2043 | AMERICAN EAGLES (15-8, 7-5, 7-6 Away)* | - | | | | |
| February 23, 2043 | @ Colgate Raiders (12-11, 6-6, 7-3 Home)* | - | | | | |
| February 27, 2043 | @ Lehigh Mountain Hawks (6-17, 5-7, 5-6 Home)* | - | | | | |
| March 2, 2043 | ARMY BLACK KNIGHTS (11-12, 6-6, 5-8 Away)* | - | | | | |
