| November 21, 2042 | @ West Georgia Wolves | W 64-50 | 1-0 | R. Wilkins 21 | J. McArthur 4 | B. Espinoza 10 |
| November 26, 2042 | @ DePaul Blue Demons | L 75-98 | 1-1 | E. Holmes 16 | J. McArthur 7 | R. Wilkins 5 |
| November 28, 2042 | KENNESAW STATE OWLS | W 89-75 | 2-1 | E. Holmes 19 | B. Espinoza 5 | E. Holmes 6 |
| December 2, 2042 | ST. BONAVENTURE BONNIES | W 97-72 | 3-1 | B. Espinoza 24 | R. Graves 6 | R. Graves 9 |
| December 5, 2042 | FLORIDA GULF COAST EAGLES | L 71-77 | 3-2 | B. Espinoza 17 | J. McArthur 7 | R. Wilkins 5 |
| December 9, 2042 | @ South Carolina Gamecocks | L 70-79 | 3-3 | B. Espinoza 16 | B. Espinoza 4 | B. Espinoza 7 |
| December 13, 2042 | @ Texas Southern Tigers | L 73-79 | 3-4 | B. Espinoza 15 | R. Wilkins 5 | R. Graves 7 |
| December 17, 2042 | STONY BROOK SEAWOLVES | W 83-64 | 4-4 | E. Holmes 18 | R. Wilkins 6 | E. Holmes 11 |
| December 20, 2042 | @ Tennessee State Tigers | L 78-90 | 4-5 | B. Espinoza 18 | J. McArthur 5 | B. Espinoza 9 |
| December 26, 2042 | @ Stephen F. Austin Lumberjacks (4-5, 0-0, 4-1 Home)* | - | | | | |
| December 29, 2042 | @ McNeese Cowboys (3-6, 0-0, 1-1 Home)* | - | | | | |
| January 2, 2043 | LAMAR CARDINALS (1-8, 0-0, 1-6 Away)* | - | | | | |
| January 5, 2043 | NORTHWESTERN STATE DEMONS (5-4, 0-0, 3-3 Away)* | - | | | | |
| January 9, 2043 | SE LOUISIANA LIONS (4-5, 0-0, 0-4 Away)* | - | | | | |
| January 12, 2043 | @ New Orleans Privateers (6-3, 0-0, 4-1 Home)* | - | | | | |
| January 16, 2043 | NICHOLLS STATE COLONELS (3-6, 0-0, 0-3 Away)* | - | | | | |
| January 19, 2043 | @ A&M-Corpus Christi Islanders (5-4, 0-0, 4-1 Home)* | - | | | | |
| January 23, 2043 | @ East Texas A&M Lions (3-6, 0-0, 3-1 Home)* | - | | | | |
| January 26, 2043 | @ Nicholls State Colonels (3-6, 0-0, 3-2 Home)* | - | | | | |
| January 30, 2043 | A&M-CORPUS CHRISTI ISLANDERS (5-4, 0-0, 1-3 Away)* | - | | | | |
| February 2, 2043 | EAST TEXAS A&M LIONS (3-6, 0-0, 0-5 Away)* | - | | | | |
| February 6, 2043 | NEW ORLEANS PRIVATEERS (6-3, 0-0, 2-2 Away)* | - | | | | |
| February 9, 2043 | @ UT Rio Grande Valley Vaqueros (3-6, 0-0, 3-2 Home)* | - | | | | |
| February 13, 2043 | @ Lamar Cardinals (1-8, 0-0, 0-2 Home)* | - | | | | |
| February 16, 2043 | @ Northwestern State Demons (5-4, 0-0, 2-1 Home)* | - | | | | |
| February 20, 2043 | STEPHEN F. AUSTIN LUMBERJACKS (4-5, 0-0, 0-3 Away)* | - | | | | |
| February 23, 2043 | UT RIO GRANDE VALLEY VAQUEROS (3-6, 0-0, 0-4 Away)* | - | | | | |
| February 27, 2043 | MCNEESE COWBOYS (3-6, 0-0, 2-5 Away)* | - | | | | |
| March 2, 2043 | @ Incarnate Word Cardinals (6-3, 0-0, 4-0 Home)* | - | | | | |
