| November 18, 2042 | WINTHROP EAGLES Emerald Coast Classic | L 88-89 | 0-1 | J. Tolbert 24 | S. Leary 5 | G. Roland 9 |
| November 22, 2042 | BINGHAMTON BEARCATS | L 76-83 | 0-2 | R. Miner 13 | S. Leary 5 | R. Miner 9 |
| November 26, 2042 | MICHIGAN WOLVERINES | W 88-72 | 1-2 | R. Miner 16 | S. Leary 3 | R. Miner 11 |
| December 3, 2042 | #3 STANFORD CARDINAL | L 80-86 | 1-3 | J. Tolbert 19 | S. Leary 3 | R. Miner 6 |
| December 6, 2042 | ALABAMA CRIMSON TIDE | L 90-92 | 1-4 | K. Akers 21 | S. Leary 5 | K. Akers 5 |
| December 10, 2042 | @ #3 Minnesota Golden Gophers | L 62-79 | 1-5 | S. Leary 11 | S. Leary 9 | R. Miner 8 |
| December 13, 2042 | IOWA HAWKEYES | L 75-88 | 1-6 | J. Tolbert 15 | M. Evans 6 | K. Akers 7 |
| December 16, 2042 | @ South Carolina Gamecocks | L 76-81 | 1-7 | J. Tolbert 16 | S. Leary 6 | R. Miner 9 |
| December 23, 2042 | UMASS LOWELL RIVER HAWKS | W 76-71 | 2-7 | K. Akers 22 | S. Leary 4 | R. Miner 9 |
| December 28, 2042 | @ Kansas Jayhawks (10-1, 0-0, 6-0 Home)* | - | | | | |
| December 30, 2042 | KANSAS STATE WILDCATS (5-5, 0-0, 1-1 Away)* | - | | | | |
| January 4, 2043 | @ UCF Knights (5-4, 0-0, 5-0 Home)* | - | | | | |
| January 6, 2043 | COLORADO BUFFALOES (6-4, 0-0, 1-1 Away)* | - | | | | |
| January 9, 2043 | WEST VIRGINIA MOUNTAINEERS (9-2, 0-0, 0-1 Away)* | - | | | | |
| January 13, 2043 | @ Oklahoma State Cowboys (10-1, 0-0, 8-0 Home)* | - | | | | |
| January 18, 2043 | @ TCU Horned Frogs (7-3, 0-0, 6-0 Home)* | - | | | | |
| January 20, 2043 | TEXAS TECH RED RAIDERS (6-4, 0-0, 1-2 Away)* | - | | | | |
| January 25, 2043 | @ Kansas State Wildcats (5-5, 0-0, 2-4 Home)* | - | | | | |
| January 27, 2043 | CINCINNATI BEARCATS (8-2, 0-0, 0-0 Away)* | - | | | | |
| February 1, 2043 | HOUSTON COUGARS (7-2, 0-0, 0-2 Away)* | - | | | | |
| February 6, 2043 | @ Arizona Wildcats (3-6, 0-0, 3-2 Home)* | - | | | | |
| February 8, 2043 | @ BYU Cougars (7-3, 0-0, 5-0 Home)* | - | | | | |
| February 10, 2043 | ARIZONA STATE SUN DEVILS (7-3, 0-0, 1-0 Away)* | - | | | | |
| February 15, 2043 | BAYLOR BEARS (11-1, 0-0, 1-0 Away)* | - | | | | |
| February 20, 2043 | @ Houston Cougars (7-2, 0-0, 7-0 Home)* | - | | | | |
| February 22, 2043 | KANSAS JAYHAWKS (10-1, 0-0, 1-1 Away)* | - | | | | |
| February 24, 2043 | @ Utah Utes (7-4, 0-0, 5-3 Home)* | - | | | | |
| March 1, 2043 | @ Cincinnati Bearcats (8-2, 0-0, 6-2 Home)* | - | | | | |
| March 3, 2043 | BYU COUGARS (7-3, 0-0, 1-2 Away)* | - | | | | |
