| November 16, 2042 | @ SMU Mustangs | L 73-88 | 0-1 | C. Milner 13 | C. Milner 2 | M. Townsend 9 |
| November 19, 2042 | @ Illinois Fighting Illini | L 60-75 | 0-2 | L. Lewis 14 | C. Milner 3 | L. Lewis 6 |
| November 21, 2042 | @ Miami (FL) Hurricanes WSSN Classic | L 73-91 | 0-3 | L. Lewis 17 | C. Milner 4 | A. Craft 7 |
| November 24, 2042 | NORTHERN COLORADO BEARS | W 85-74 | 1-3 | R. Hunt 17 | C. Milner 8 | A. Craft 10 |
| November 29, 2042 | RADFORD HIGHLANDERS | W 71-56 | 2-3 | S. Villarreal 14 | C. Milner 5 | M. Townsend 8 |
| December 3, 2042 | OMAHA MAVERICKS | W 71-55 | 3-3 | C. Milner 18 | C. Milner 8 | M. Townsend 9 |
| December 7, 2042 | @ Michigan State Spartans | L 56-76 | 3-4 | L. Lewis 11 | C. Milner 5 | M. Townsend 7 |
| December 13, 2042 | @ Lindenwood Lions | L 62-78 | 3-5 | S. Villarreal 12 | C. Milner 4 | M. Townsend 9 |
| December 20, 2042 | CENTRAL MICHIGAN CHIPPEWAS | L 64-75 | 3-6 | S. Villarreal 13 | C. Milner 5 | A. Craft 10 |
| December 26, 2042 | @ Drake Bulldogs* | L 80-83 OT | 3-7 | L. Lewis 15 | C. Milner 5 | M. Townsend 9 |
| December 29, 2042 | @ Evansville Purple Aces* | L 77-95 | 3-8 | C. Milner 15 | C. Milner 5 | M. Townsend 8 |
| January 2, 2043 | @ Indiana State Sycamores* | L 61-78 | 3-9 | A. Craft 12 | C. Milner 6 | A. Craft 9 |
| January 5, 2043 | @ Missouri State Bears* | W 91-83 | 4-9 | A. Craft 17 | C. Milner 3 | M. Townsend 13 |
| January 9, 2043 | VALPARAISO CRUSADERS* | W 78-52 | 5-9 | S. Villarreal 13 | M. Townsend 3 | M. Townsend 6 |
| January 12, 2043 | SOUTHERN ILLINOIS SALUKIS* | W 73-60 | 6-9 | S. Villarreal 12 | C. Milner 7 | A. Craft 14 |
| January 16, 2043 | BRADLEY BRAVES* | W 75-58 | 7-9 | A. Craft 17 | C. Milner 5 | L. Lewis 8 |
| January 19, 2043 | @ Northern Iowa Panthers* | L 61-79 | 7-10 | M. Townsend 12 | C. Milner 4 | L. Lewis 6 |
| January 23, 2043 | @ UIC Flames* | L 68-75 | 7-11 | A. Craft 23 | B. Collier 3 | A. Craft 7 |
| January 26, 2043 | BELMONT BRUINS* | L 67-69 | 7-12 | A. Craft 17 | C. Milner 7 | C. Ferrell 9 |
| January 30, 2043 | NORTHERN IOWA PANTHERS* | W 87-73 | 8-12 | S. Villarreal 24 | C. Milner 5 | L. Lewis 5 |
| February 2, 2043 | UIC FLAMES* | L 69-80 | 8-13 | A. Craft 15 | C. Milner 5 | A. Craft 9 |
| February 6, 2043 | @ Southern Illinois Salukis* | W 80-70 | 9-13 | C. Milner 26 | L. Lewis 5 | A. Craft 9 |
| February 9, 2043 | @ Bradley Braves* | W 73-70 | 10-13 | C. Milner 16 | C. Milner 4 | A. Craft 10 |
| February 13, 2043 | INDIANA STATE SYCAMORES* | L 68-75 | 10-14 | L. Lewis 13 | C. Milner 7 | L. Lewis 8 |
| February 16, 2043 | MISSOURI STATE BEARS* | L 82-89 | 10-15 | A. Craft 14 | C. Milner 5 | R. Hunt 9 |
| February 20, 2043 | DRAKE BULLDOGS* | W 76-67 | 11-15 | C. Ferrell 17 | C. Milner 2 | A. Craft 9 |
| February 23, 2043 | EVANSVILLE PURPLE ACES* | L 66-92 | 11-16 | S. Villarreal 16 | R. Hunt 4 | A. Craft 6 |
| February 27, 2043 | @ Belmont Bruins* | L 72-87 | 11-17 | S. Villarreal 21 | C. Milner 10 | A. Craft 8 |
| March 2, 2043 | @ Murray State Racers* | L 48-67 | 11-18 | A. Craft 8 | C. Milner 2 | S. Villarreal 9 |
| March 6, 2043 | BELMONT BRUINS MVC Tournament | W 83-79 | 12-18 | L. Lewis 15 | C. Milner 7 | S. Villarreal 10 |
| March 7, 2043 | @ Indiana State Sycamores MVC Tournament | W 82-75 | 13-18 | L. Lewis 17 | C. Milner 4 | M. Townsend 10 |
| March 8, 2043 | BRADLEY BRAVES MVC Tournament | W 94-79 | 14-18 | L. Lewis 17 | C. Milner 6 | A. Craft 9 |
| March 9, 2043 | MISSOURI STATE BEARS MVC Tournament | L 71-82 | 14-19 | A. Craft 16 | C. Milner 3 | M. Townsend 9 |
