| November 15, 2042 | @ Rice Owls | W 96-81 | 1-0 | J. Burrough 21 | E. Rosas 7 | V. Underwood 10 |
| November 18, 2042 | @ Eastern Washington Eagles | W 88-76 | 2-0 | L. Harris 14 | R. Toledo 3 | L. Harris 7 |
| November 22, 2042 | SAINT JOSEPH'S HAWKS | L 61-64 | 2-1 | V. Underwood 15 | R. Toledo 3 | L. Harris 7 |
| November 25, 2042 | STEPHEN F. AUSTIN LUMBERJACKS ESPN Events Invitational | W 92-69 | 3-1 | J. Blackwell 16 | R. Toledo 9 | L. Harris 10 |
| November 26, 2042 | @ Western Kentucky Hilltoppers ESPN Events Invitational | W 96-90 | 4-1 | V. Underwood 17 | R. Toledo 8 | V. Underwood 8 |
| November 27, 2042 | @ Bucknell Bison ESPN Events Invitational | W 102-75 | 5-1 | V. Underwood 21 | J. Burrough 4 | V. Underwood 12 |
| November 29, 2042 | MARSHALL THUNDERING HERD | W 82-68 | 6-1 | L. May 16 | R. Toledo 7 | T. Smith 8 |
| December 2, 2042 | @ Villanova Wildcats | L 85-88 | 6-2 | L. May 19 | L. May 4 | V. Underwood 9 |
| December 7, 2042 | @ UTSA Roadrunners | L 92-94 | 6-3 | L. May 18 | J. Blackwell 7 | J. Burrough 7 |
| December 13, 2042 | IU INDY JAGUARS | W 84-55 | 7-3 | L. Harris 23 | L. May 5 | J. Burrough 7 |
| December 20, 2042 | @ Liberty Flames | W 74-60 | 8-3 | L. May 15 | J. Blackwell 5 | T. Smith 14 |
| December 26, 2042 | @ Northern Iowa Panthers (3-6, 0-0, 2-2 Home)* | - | | | | |
| December 29, 2042 | @ UIC Flames (3-6, 0-0, 1-3 Home)* | - | | | | |
| January 2, 2043 | ILLINOIS STATE REDBIRDS (3-6, 0-0, 0-4 Away)* | - | | | | |
| January 5, 2043 | BELMONT BRUINS (7-3, 0-0, 4-2 Away)* | - | | | | |
| January 9, 2043 | DRAKE BULLDOGS (0-9, 0-0, 0-3 Away)* | - | | | | |
| January 12, 2043 | @ Valparaiso Crusaders (6-3, 0-0, 4-1 Home)* | - | | | | |
| January 16, 2043 | MURRAY STATE RACERS (7-2, 0-0, 3-1 Away)* | - | | | | |
| January 19, 2043 | @ Southern Illinois Salukis (4-5, 0-0, 4-2 Home)* | - | | | | |
| January 23, 2043 | @ Bradley Braves (4-5, 0-0, 3-3 Home)* | - | | | | |
| January 26, 2043 | @ Murray State Racers (7-2, 0-0, 4-0 Home)* | - | | | | |
| January 30, 2043 | SOUTHERN ILLINOIS SALUKIS (4-5, 0-0, 0-3 Away)* | - | | | | |
| February 2, 2043 | BRADLEY BRAVES (4-5, 0-0, 1-2 Away)* | - | | | | |
| February 6, 2043 | VALPARAISO CRUSADERS (6-3, 0-0, 2-2 Away)* | - | | | | |
| February 9, 2043 | MISSOURI STATE BEARS (5-5, 0-0, 4-3 Away)* | - | | | | |
| February 13, 2043 | @ Illinois State Redbirds (3-6, 0-0, 3-1 Home)* | - | | | | |
| February 16, 2043 | @ Belmont Bruins (7-3, 0-0, 2-0 Home)* | - | | | | |
| February 20, 2043 | NORTHERN IOWA PANTHERS (3-6, 0-0, 1-3 Away)* | - | | | | |
| February 23, 2043 | @ Missouri State Bears (5-5, 0-0, 0-1 Home)* | - | | | | |
| February 27, 2043 | UIC FLAMES (3-6, 0-0, 2-2 Away)* | - | | | | |
| March 2, 2043 | @ Evansville Purple Aces (5-4, 0-0, 3-2 Home)* | - | | | | |
