| November 14, 2043 | NIAGARA PURPLE EAGLES | W 101-79 | 1-0 | L. Hayes 27 | L. Hayes 5 | W. Hudson 12 |
| November 17, 2043 | SANTA CLARA BRONCOS | W 81-72 | 2-0 | W. Hudson 21 | L. Hayes 6 | W. Hudson 11 |
| November 21, 2043 | CENTRAL MICHIGAN CHIPPEWAS | W 112-96 | 3-0 | M. Giordano 38 | L. Hayes 14 | D. Crowder 12 |
| November 24, 2043 | BELMONT BRUINS | W 79-68 | 4-0 | M. Giordano 20 | L. Hayes 9 | D. Vitale 11 |
| November 28, 2043 | CAL ST. NORTHRIDGE MATADORS | W 94-71 | 5-0 | M. Giordano 21 | L. Hayes 7 | D. Crowder 11 |
| December 5, 2043 | @ Nevada Wolfpack | W 106-97 | 6-0 | M. Giordano 40 | L. Hayes 10 | D. Vitale 11 |
| December 10, 2043 | #14 RHODE ISLAND RAMS | W 101-86 | 7-0 | M. Giordano 30 | L. Hayes 11 | D. Crowder 8 |
| December 13, 2043 | VANDERBILT COMMODORES | W 77-75 | 8-0 | M. Giordano 17 | L. Hayes 5 | D. Crowder 9 |
| December 19, 2043 | UNC ASHEVILLE BULLDOGS | W 90-54 | 9-0 | L. Hayes 30 | D. Vitale 8 | W. Hudson 11 |
| December 26, 2043 | @ USC Trojans* | L 86-91 | 9-1 | W. Hudson 22 | L. Hayes 7 | W. Hudson 10 |
| December 28, 2043 | ILLINOIS FIGHTING ILLINI* | L 73-76 | 9-2 | W. Hudson 29 | L. Hayes 8 | W. Hudson 12 |
| January 2, 2044 | @ Washington Huskies* | W 89-71 | 10-2 | L. Hayes 29 | L. Hayes 9 | D. Vitale 11 |
| January 4, 2044 | OREGON DUCKS* | W 87-80 | 11-2 | L. Hayes 20 | L. Hayes 9 | M. Giordano 9 |
| January 9, 2044 | @ #17 Maryland Terrapins* | L 63-80 | 11-3 | L. Hayes 17 | L. Hayes 4 | D. Vitale 8 |
| January 11, 2044 | NEBRASKA CORNHUSKERS* | W 105-75 | 12-3 | M. Giordano 29 | L. Hayes 11 | W. Hudson 10 |
| January 16, 2044 | OHIO STATE BUCKEYES* | W 71-56 | 13-3 | M. Giordano 20 | L. Hayes 3 | D. Crowder 18 |
| January 18, 2044 | UCLA BRUINS* | W 105-86 | 14-3 | W. Hudson 29 | L. Hayes 6 | D. Vitale 11 |
| January 23, 2044 | @ Michigan Wolverines* | L 69-80 | 14-4 | M. Giordano 17 | L. Hayes 6 | D. Crowder 9 |
| January 25, 2044 | RUTGERS SCARLET KNIGHTS* | W 87-73 | 15-4 | M. Giordano 27 | L. Hayes 7 | W. Hudson 8 |
| January 30, 2044 | @ #22 Penn State Nittany Lions* | L 76-88 | 15-5 | D. Crowder 17 | L. Hayes 7 | D. Crowder 9 |
| February 1, 2044 | @ Michigan State Spartans* | W 82-76 | 16-5 | M. Giordano 23 | M. Giordano 5 | M. Giordano 9 |
| February 6, 2044 | @ Wisconsin Badgers* | W 93-63 | 17-5 | M. Giordano 24 | L. Hayes 16 | D. Crowder 9 |
| February 8, 2044 | @ Northwestern Wildcats* | W 96-77 | 18-5 | W. Hudson 38 | L. Hayes 8 | W. Hudson 14 |
| February 13, 2044 | #4 MINNESOTA GOLDEN GOPHERS* | W 87-74 | 19-5 | M. Giordano 33 | L. Hayes 8 | W. Hudson 11 |
| February 15, 2044 | IOWA HAWKEYES* | W 79-68 | 20-5 | W. Hudson 25 | L. Hayes 5 | W. Hudson 10 |
| February 20, 2044 | PURDUE BOILERMAKERS* | W 98-80 | 21-5 | M. Giordano 31 | L. Hayes 11 | W. Hudson 13 |
| February 22, 2044 | @ Ohio State Buckeyes* | W 76-44 | 22-5 | L. Hayes 29 | L. Hayes 6 | W. Hudson 14 |
| February 27, 2044 | USC TROJANS* | L 90-91 | 22-6 | M. Giordano 28 | L. Hayes 11 | D. Crowder 10 |
| March 1, 2044 | @ #5 Minnesota Golden Gophers* | W 95-81 | 23-6 | L. Hayes 27 | L. Hayes 7 | W. Hudson 9 |
| March 10, 2044 | NORTHWESTERN WILDCATS (17-14, 5-7 Away) Big 10 Tournament | - | | | | |