| November 16, 2042 | BOWLING GREEN FALCONS | W 82-60 | 1-0 | M. Henry 15 | D. Wu 4 | D. Wu 12 |
| November 23, 2042 | IU INDY JAGUARS | W 80-57 | 2-0 | B. Hall 14 | C. Stewart 4 | D. Wu 11 |
| November 26, 2042 | STONY BROOK SEAWOLVES | W 86-70 | 3-0 | D. Wu 24 | M. Henry 6 | D. Wu 15 |
| November 30, 2042 | @ #24 Syracuse Orange | W 75-57 | 4-0 | C. Clay 18 | M. Henry 12 | D. Wu 13 |
| December 3, 2042 | @ Kentucky Wildcats | W 90-69 | 5-0 | C. Stewart 21 | M. Henry 6 | B. Hall 14 |
| December 7, 2042 | SOUTH CAROLINA GAMECOCKS | W 75-66 | 6-0 | C. Clay 18 | M. Henry 5 | D. Wu 14 |
| December 13, 2042 | @ Iowa State Cyclones | W 88-75 | 7-0 | C. Stewart 18 | M. Henry 7 | B. Hall 10 |
| December 21, 2042 | @ Utah Utes | L 80-82 | 7-1 | D. Wu 18 | C. Stewart 5 | B. Hall 15 |
| December 23, 2042 | VANDERBILT COMMODORES saatva Empire Classic | W 89-77 | 8-1 | D. Wu 19 | B. Hall 6 | B. Hall 12 |
| December 24, 2042 | @ Fresno State Bulldogs saatva Empire Classic | W 83-60 | 9-1 | D. Wu 22 | C. Clay 4 | D. Wu 14 |
| December 25, 2042 | @ Kansas State Wildcats (5-5, 2-4 Home) saatva Empire Classic | - | | | | |
| December 26, 2042 | @ Michigan Wolverines (4-5, 0-0, 4-2 Home)* | - | | | | |
| December 28, 2042 | @ UCLA Bruins (5-5, 0-0, 4-3 Home)* | - | | | | |
| January 2, 2043 | MINNESOTA GOLDEN GOPHERS (9-2, 0-0, 2-0 Away)* | - | | | | |
| January 4, 2043 | PURDUE BOILERMAKERS (10-1, 0-0, 0-0 Away)* | - | | | | |
| January 9, 2043 | NEBRASKA CORNHUSKERS (3-6, 0-0, 0-2 Away)* | - | | | | |
| January 11, 2043 | INDIANA HOOSIERS (7-4, 0-0, 1-3 Away)* | - | | | | |
| January 16, 2043 | @ Penn State Nittany Lions (6-3, 0-0, 5-0 Home)* | - | | | | |
| January 18, 2043 | WISCONSIN BADGERS (5-4, 0-0, 0-1 Away)* | - | | | | |
| January 23, 2043 | WASHINGTON HUSKIES (3-6, 0-0, 0-3 Away)* | - | | | | |
| January 25, 2043 | NORTHWESTERN WILDCATS (5-6, 0-0, 1-2 Away)* | - | | | | |
| January 30, 2043 | @ Rutgers Scarlet Knights (8-1, 0-0, 8-0 Home)* | - | | | | |
| February 1, 2043 | @ Illinois Fighting Illini (7-2, 0-0, 5-0 Home)* | - | | | | |
| February 6, 2043 | USC TROJANS (8-2, 0-0, 0-2 Away)* | - | | | | |
| February 8, 2043 | @ Ohio State Buckeyes (4-5, 0-0, 4-3 Home)* | - | | | | |
| February 13, 2043 | @ Maryland Terrapins (7-3, 0-0, 5-0 Home)* | - | | | | |
| February 15, 2043 | OREGON DUCKS (4-5, 0-0, 0-2 Away)* | - | | | | |
| February 20, 2043 | MICHIGAN STATE SPARTANS (7-3, 0-0, 1-3 Away)* | - | | | | |
| February 22, 2043 | @ Oregon Ducks (4-5, 0-0, 4-2 Home)* | - | | | | |
| February 27, 2043 | @ Northwestern Wildcats (5-6, 0-0, 2-3 Home)* | - | | | | |
| March 1, 2043 | @ Purdue Boilermakers (10-1, 0-0, 7-1 Home)* | - | | | | |
