| November 15, 2039 |  EASTERN MICHIGAN EAGLES | W 82-47 | 1-0 | D. Reyes 21 | G. Cameron 8 | D. Greene 8 |
| November 18, 2039 |  LIBERTY FLAMES | W 99-68 | 2-0 | A. Ware 18 | G. Cameron 8 | C. Clay 10 |
| November 22, 2039 |  #15 FLORIDA STATE SEMINOLES | W 89-75 | 3-0 | D. Greene 23 | G. Cameron 6 | D. Greene 8 |
| November 25, 2039 |  TEXAS STATE BOBCATS  ESPN Events Invitational | W 85-65 | 4-0 | A. Ware 18 | D. Reyes 4 | C. Clay 7 |
| November 26, 2039 |  @ Utah State Aggies ESPN Events Invitational | W 71-53 | 5-0 | D. Greene 16 | G. Cameron 6 | C. Clay 9 |
| November 27, 2039 |  @ Creighton Blue Jays ESPN Events Invitational | L 81-82 | 5-1 | D. Greene 15 | R. Crenshaw 6 | D. Greene 6 |
| November 29, 2039 |  SOUTH DAKOTA STATE JACKRABBITS | W 80-65 | 6-1 | A. Ware 18 | G. Cameron 7 | D. Greene 10 |
| December 2, 2039 |  ALCORN STATE BRAVES | W 79-55 | 7-1 | G. Cameron 20 | D. Greene 7 | D. Greene 9 |
| December 6, 2039 |  DREXEL DRAGONS | W 81-70 | 8-1 | C. Clay 16 | G. Cameron 5 | C. Clay 9 |
| December 13, 2039 |  IOWA STATE CYCLONES | W 90-80 | 9-1 | A. Ware 15 | G. Cameron 6 | D. Greene 8 |
| December 20, 2039 |  SOUTHERN JAGUARS | W 81-74 | 10-1 | G. Cameron 16 | G. Cameron 7 | C. Clay 8 |
| December 26, 2039 |  NEBRASKA CORNHUSKERS* | W 80-49 | 11-1 | C. Clay 15 | A. Ware 5 | D. Greene 9 |
| December 28, 2039 |  @ Ohio State Buckeyes* | L 70-77 | 11-2 | A. Ware 25 | D. Reyes 5 | D. Greene 10 |
| January 2, 2040 |  NORTHWESTERN WILDCATS* | W 81-64 | 12-2 | C. Clay 17 | K. Britt 5 | C. Clay 9 |
| January 4, 2040 |  RUTGERS SCARLET KNIGHTS* | L 57-65 | 12-3 | G. Cameron 12 | G. Cameron 4 | G. Cameron 7 |
| January 9, 2040 |  @ #22 Michigan Wolverines* | L 67-77 | 12-4 | A. Ware 19 | G. Cameron 7 | G. Cameron 7 |
| January 13, 2040 |  ILLINOIS FIGHTING ILLINI* | W 71-58 | 13-4 | A. Ware 15 | D. Greene 5 | D. Greene 8 |
| January 18, 2040 |  @ Wisconsin Badgers* | W 72-69 | 14-4 | C. Clay 16 | G. Cameron 5 | D. Greene 7 |
| January 23, 2040 | @ Rutgers Scarlet Knights* | L 62-76 | 14-5 | A. Ware 20 | K. Britt 3 | G. Cameron 7 |
| January 25, 2040 | OHIO STATE BUCKEYES* | W 70-62 | 15-5 | K. Britt 21 | G. Cameron 7 | D. Greene 7 |
| January 27, 2040 | @ Illinois Fighting Illini* | W 80-68 | 16-5 | D. Greene 15 | D. Greene 6 | D. Greene 10 |
| February 1, 2040 |  INDIANA HOOSIERS* | W 73-63 | 17-5 | D. Greene 14 | G. Cameron 4 | D. Greene 6 |
| February 3, 2040 | @ Northwestern Wildcats* | L 59-67 | 17-6 | G. Cameron 12 | D. Greene 3 | D. Greene 10 |
| February 6, 2040 | @ Nebraska Cornhuskers* | W 90-76 | 18-6 | C. Clay 25 | K. Britt 6 | C. Clay 11 |
| February 10, 2040 |  MICHIGAN STATE SPARTANS* | W 84-65 | 19-6 | A. Ware 23 | G. Cameron 6 | D. Greene 10 |
| February 15, 2040 |  @ Penn State Nittany Lions* | L 73-77 | 19-7 | K. Britt 15 | G. Cameron 6 | G. Cameron 7 |
| February 17, 2040 |  #4 MINNESOTA GOLDEN GOPHERS* | W 77-70 | 20-7 | C. Clay 17 | G. Cameron 4 | C. Clay 10 |
| February 22, 2040 |  PURDUE BOILERMAKERS* | L 68-74 | 20-8 | D. Palmer 15 | G. Cameron 5 | C. Clay 11 |
| February 24, 2040 | @ Michigan State Spartans* | L 55-89 | 20-9 | C. Clay 15 | K. Britt 2 | D. Greene 8 |
| March 1, 2040 | @ Indiana Hoosiers* | W 83-73 | 21-9 | A. Ware 15 | K. Britt 7 | G. Cameron 6 |
| March 3, 2040 |  #3 MARYLAND TERRAPINS* | L 57-65 | 21-10 | S. Estrada 11 | K. Britt 4 | E. Irvin 7 |
| March 8, 2040 | MICHIGAN STATE SPARTANS  Big 10 Tournament | W 83-77 | 22-10 | A. Ware 26 | G. Cameron 7 | E. Irvin 11 |
| March 9, 2040 | @ #2 Maryland Terrapins Big 10 Tournament | L 66-80 | 22-11 | A. Ware 14 | G. Cameron 5 | D. Greene 9 |
