| November 16, 2042 | PRINCETON TIGERS | L 70-74 | 0-1 | A. Strandmark 17 | J. Pratt 4 | J. Pratt 15 |
| November 19, 2042 | @ Mississippi State Bulldogs | W 80-61 | 1-1 | A. Strandmark 21 | J. Mitchell 4 | J. Pratt 9 |
| November 23, 2042 | TEXAS SOUTHERN TIGERS | W 72-58 | 2-1 | J. Pratt 21 | A. Strandmark 4 | J. Pratt 20 |
| November 26, 2042 | PENN STATE NITTANY LIONS | W 94-78 | 3-1 | A. Strandmark 23 | I. Shaw 9 | J. Pratt 11 |
| November 30, 2042 | MURRAY STATE RACERS | W 77-63 | 4-1 | M. Alford 20 | I. Shaw 8 | M. Alford 15 |
| December 7, 2042 | @ Colorado Buffaloes | W 92-84 | 5-1 | A. Strandmark 26 | I. Shaw 5 | M. Alford 6 |
| December 13, 2042 | @ Kentucky Wildcats | W 82-71 | 6-1 | A. Strandmark 20 | I. Shaw 7 | L. Sherwood 7 |
| December 16, 2042 | NEW MEXICO LOBOS Diamond Head Classic | W 97-73 | 7-1 | M. Alford 23 | I. Shaw 6 | M. Alford 11 |
| December 17, 2042 | TCU HORNED FROGS Diamond Head Classic | W 80-77 OT | 8-1 | L. Sherwood 14 | I. Shaw 4 | M. Alford 12 |
| December 18, 2042 | #21 ALABAMA CRIMSON TIDE Diamond Head Classic | L 68-97 | 8-2 | A. Strandmark 10 | L. Sherwood 3 | M. Alford 7 |
| December 21, 2042 | ARIZONA WILDCATS | W 94-87 | 9-2 | C. Higgins 17 | I. Shaw 6 | M. Alford 7 |
| December 26, 2042 | BOSTON COLLEGE EAGLES* | W 94-71 | 10-2 | I. Shaw 16 | I. Shaw 4 | M. Alford 8 |
| December 28, 2042 | @ Duke Blue Devils* | L 84-89 OT | 10-3 | M. Alford 17 | I. Shaw 8 | A. Strandmark 6 |
| January 2, 2043 | @ Wake Forest Demon Deacons* | L 58-92 | 10-4 | R. Kaufman 11 | I. Shaw 3 | L. Sherwood 8 |
| January 4, 2043 | #14 NOTRE DAME FIGHTING IRISH* | W 86-84 | 11-4 | L. Sherwood 17 | I. Shaw 5 | L. Sherwood 7 |
| January 9, 2043 | SYRACUSE ORANGE* | L 62-79 | 11-5 | A. Strandmark 12 | M. Alford 4 | A. Strandmark 6 |
| January 11, 2043 | #21 MIAMI (FL) HURRICANES* | W 80-68 | 12-5 | L. Sherwood 16 | I. Shaw 6 | R. Kaufman 8 |
| January 16, 2043 | #7 STANFORD CARDINAL* | L 75-80 | 12-6 | L. Sherwood 19 | I. Shaw 3 | L. Sherwood 9 |
| January 18, 2043 | @ Pittsburgh Panthers* | L 65-74 | 12-7 | M. Alford 18 | A. Strandmark 3 | M. Alford 10 |
| January 23, 2043 | #2 NORTH CAROLINA TAR HEELS* | L 73-85 | 12-8 | L. Sherwood 15 | I. Shaw 3 | E. Marks 5 |
| January 25, 2043 | @ Florida State Seminoles* | L 56-76 | 12-9 | M. Alford 17 | I. Shaw 2 | L. Sherwood 7 |
| January 30, 2043 | CALIFORNIA GOLDEN BEARS* | W 106-94 | 13-9 | M. Alford 23 | I. Shaw 6 | L. Sherwood 8 |
| February 1, 2043 | @ NC State Wolfpack* | L 62-76 | 13-10 | I. Shaw 15 | I. Shaw 4 | M. Alford 5 |
| February 6, 2043 | GEORGIA TECH YELLOW JACKETS* | W 82-61 | 14-10 | M. Alford 26 | I. Shaw 6 | M. Alford 11 |
| February 8, 2043 | @ Virginia Cavaliers* | W 101-80 | 15-10 | L. Sherwood 25 | I. Shaw 10 | E. Marks 8 |
| February 13, 2043 | @ Clemson Tigers (7-16, 5-9, 4-7 Home)* | - | | | | |
| February 15, 2043 | @ Virginia Tech Hokies (4-20, 0-14, 3-9 Home)* | - | | | | |
| February 20, 2043 | @ SMU Mustangs (13-11, 7-7, 9-4 Home)* | - | | | | |
| February 22, 2043 | VIRGINIA CAVALIERS (9-14, 7-7, 3-9 Away)* | - | | | | |
| February 27, 2043 | @ Notre Dame Fighting Irish (19-7, 11-3, 10-1 Home)* | - | | | | |
| March 1, 2043 | NC STATE WOLFPACK (15-8, 9-5, 3-5 Away)* | - | | | | |
