| November 16, 2042 | KANSAS CITY KANGAROOS | W 73-58 | 1-0 | G. Cox 22 | H. McMahan 8 | G. Cox 21 |
| November 19, 2042 | IU INDY JAGUARS | W 69-52 | 2-0 | N. Stevenson 19 | H. McMahan 6 | G. Cox 11 |
| November 23, 2042 | @ Kentucky Wildcats | W 90-86 | 3-0 | H. McMahan 20 | H. McMahan 11 | G. Cox 10 |
| November 30, 2042 | INCARNATE WORD CARDINALS | L 68-73 | 3-1 | T. Singletary 13 | H. McMahan 7 | N. Stevenson 8 |
| December 1, 2042 | JACKSONVILLE DOLPHINS | L 74-85 | 3-2 | N. Stevenson 30 | H. McMahan 4 | G. Cox 13 |
| December 7, 2042 | RICE OWLS | W 81-57 | 4-2 | G. Cox 21 | H. McMahan 6 | G. Cox 11 |
| December 13, 2042 | @ Wisconsin Badgers | L 76-83 | 4-3 | G. Cox 17 | H. McMahan 6 | G. Cox 9 |
| December 21, 2042 | DUQUESNE DUKES | W 63-53 | 5-3 | D. Davis 21 | H. McMahan 3 | G. Cox 14 |
| December 23, 2042 | FRESNO STATE BULLDOGS saatva Empire Classic | L 103-105 | 5-4 | N. Stevenson 25 | C. Bair 4 | N. Stevenson 8 |
| December 26, 2042 | VILLANOVA WILDCATS (5-4, 0-0, 1-1 Away)* | - | | | | |
| December 28, 2042 | @ Providence Friars (4-5, 0-0, 3-2 Home)* | - | | | | |
| December 30, 2042 | @ Butler Bulldogs (6-4, 0-0, 4-1 Home)* | - | | | | |
| January 2, 2043 | CONNECTICUT HUSKIES (7-4, 0-0, 1-2 Away)* | - | | | | |
| January 4, 2043 | @ Xavier Musketeers (8-2, 0-0, 6-0 Home)* | - | | | | |
| January 9, 2043 | CREIGHTON BLUE JAYS (9-2, 0-0, 3-1 Away)* | - | | | | |
| January 13, 2043 | DEPAUL BLUE DEMONS (3-7, 0-0, 0-1 Away)* | - | | | | |
| January 18, 2043 | @ St. John's Red Storm (6-5, 0-0, 4-1 Home)* | - | | | | |
| January 20, 2043 | @ Georgetown Hoyas (2-8, 0-0, 1-1 Home)* | - | | | | |
| January 25, 2043 | @ Creighton Blue Jays (9-2, 0-0, 3-1 Home)* | - | | | | |
| January 27, 2043 | @ Seton Hall Pirates (8-1, 0-0, 8-0 Home)* | - | | | | |
| February 1, 2043 | XAVIER MUSKETEERS (8-2, 0-0, 1-1 Away)* | - | | | | |
| February 3, 2043 | @ DePaul Blue Demons (3-7, 0-0, 2-5 Home)* | - | | | | |
| February 8, 2043 | GEORGETOWN HOYAS (2-8, 0-0, 0-6 Away)* | - | | | | |
| February 10, 2043 | ST. JOHN'S RED STORM (6-5, 0-0, 0-3 Away)* | - | | | | |
| February 17, 2043 | SETON HALL PIRATES (8-1, 0-0, 0-1 Away)* | - | | | | |
| February 22, 2043 | @ Connecticut Huskies (7-4, 0-0, 4-1 Home)* | - | | | | |
| February 24, 2043 | @ Villanova Wildcats (5-4, 0-0, 4-2 Home)* | - | | | | |
| March 1, 2043 | BUTLER BULLDOGS (6-4, 0-0, 1-2 Away)* | - | | | | |
| March 3, 2043 | PROVIDENCE FRIARS (4-5, 0-0, 1-2 Away)* | - | | | | |
