| November 16, 2042 | KANSAS CITY KANGAROOS | W 73-58 | 1-0 | G. Cox 22 | H. McMahan 8 | G. Cox 21 |
| November 19, 2042 | IU INDY JAGUARS | W 69-52 | 2-0 | N. Stevenson 19 | H. McMahan 6 | G. Cox 11 |
| November 23, 2042 | @ Kentucky Wildcats | W 90-86 | 3-0 | H. McMahan 20 | H. McMahan 11 | G. Cox 10 |
| November 30, 2042 | INCARNATE WORD CARDINALS | L 68-73 | 3-1 | T. Singletary 13 | H. McMahan 7 | N. Stevenson 8 |
| December 1, 2042 | JACKSONVILLE DOLPHINS | L 74-85 | 3-2 | N. Stevenson 30 | H. McMahan 4 | G. Cox 13 |
| December 7, 2042 | RICE OWLS | W 81-57 | 4-2 | G. Cox 21 | H. McMahan 6 | G. Cox 11 |
| December 13, 2042 | @ Wisconsin Badgers | L 76-83 | 4-3 | G. Cox 17 | H. McMahan 6 | G. Cox 9 |
| December 21, 2042 | DUQUESNE DUKES | W 63-53 | 5-3 | D. Davis 21 | H. McMahan 3 | G. Cox 14 |
| December 23, 2042 | FRESNO STATE BULLDOGS saatva Empire Classic | L 103-105 | 5-4 | N. Stevenson 25 | C. Bair 4 | N. Stevenson 8 |
| December 26, 2042 | VILLANOVA WILDCATS* | W 85-78 | 6-4 | G. Cox 30 | T. Singletary 4 | G. Cox 10 |
| December 28, 2042 | @ Providence Friars* | W 78-70 | 7-4 | D. Davis 22 | H. McMahan 5 | G. Cox 10 |
| December 30, 2042 | @ #24 Butler Bulldogs* | L 79-89 | 7-5 | N. Stevenson 26 | H. McMahan 5 | D. Davis 8 |
| January 2, 2043 | CONNECTICUT HUSKIES* | L 80-88 | 7-6 | G. Cox 20 | H. McMahan 4 | G. Cox 8 |
| January 4, 2043 | @ Xavier Musketeers* | L 76-81 | 7-7 | N. Stevenson 18 | H. McMahan 7 | G. Cox 10 |
| January 9, 2043 | #23 CREIGHTON BLUE JAYS* | L 63-70 | 7-8 | D. Davis 25 | H. McMahan 6 | G. Cox 8 |
| January 13, 2043 | DEPAUL BLUE DEMONS* | W 93-78 | 8-8 | N. Stevenson 23 | T. Singletary 4 | G. Cox 13 |
| January 18, 2043 | @ St. John's Red Storm* | W 79-62 | 9-8 | H. McMahan 19 | T. Singletary 4 | T. Singletary 10 |
| January 20, 2043 | @ Georgetown Hoyas* | W 81-71 | 10-8 | G. Cox 25 | T. Singletary 6 | G. Cox 18 |
| January 25, 2043 | @ #19 Creighton Blue Jays* | W 89-77 | 11-8 | G. Cox 17 | H. McMahan 8 | G. Cox 15 |
| January 27, 2043 | @ #21 Seton Hall Pirates* | L 57-75 | 11-9 | N. Stevenson 13 | T. Singletary 3 | D. Davis 10 |
| February 1, 2043 | XAVIER MUSKETEERS* | W 99-89 | 12-9 | D. Davis 25 | H. McMahan 9 | G. Cox 7 |
| February 3, 2043 | @ DePaul Blue Demons* | L 66-72 | 12-10 | T. Singletary 14 | H. McMahan 4 | G. Cox 7 |
| February 8, 2043 | GEORGETOWN HOYAS* | W 76-70 | 13-10 | N. Stevenson 19 | H. McMahan 5 | G. Cox 10 |
| February 10, 2043 | ST. JOHN'S RED STORM* | W 88-71 | 14-10 | N. Stevenson 18 | K. Turner 5 | G. Cox 11 |
| February 17, 2043 | SETON HALL PIRATES (17-6, 9-5, 2-5 Away)* | - | | | | |
| February 22, 2043 | @ Connecticut Huskies (16-10, 9-6, 10-3 Home)* | - | | | | |
| February 24, 2043 | @ Villanova Wildcats (9-15, 4-11, 8-6 Home)* | - | | | | |
| March 1, 2043 | BUTLER BULLDOGS (20-4, 14-0, 8-2 Away)* | - | | | | |
| March 3, 2043 | PROVIDENCE FRIARS (9-14, 5-9, 3-6 Away)* | - | | | | |
