| November 16, 2042 | COLORADO STATE RAMS | W 79-66 | 1-0 | C. Phipps 21 | C. Phipps 6 | C. Phipps 10 |
| November 19, 2042 | CREIGHTON BLUE JAYS | W 83-67 | 2-0 | C. Phipps 21 | J. Sims 4 | C. Phipps 13 |
| November 23, 2042 | LOYOLA MARYMOUNT LIONS | W 78-55 | 3-0 | T. Nowak 23 | J. Richardson 7 | T. Nowak 11 |
| November 30, 2042 | @ #17 Miami (FL) Hurricanes | L 77-88 | 3-1 | C. Phipps 21 | C. Phipps 7 | J. Nicholson 9 |
| December 7, 2042 | SANTA CLARA BRONCOS | W 85-73 | 4-1 | J. Nicholson 21 | C. Phipps 7 | C. Phipps 10 |
| December 10, 2042 | #6 NOTRE DAME FIGHTING IRISH | W 89-86 | 5-1 | C. Phipps 25 | J. Richardson 5 | C. Phipps 7 |
| December 13, 2042 | @ #10 West Virginia Mountaineers | L 70-85 | 5-2 | C. Phipps 26 | J. Richardson 4 | T. Nowak 13 |
| December 16, 2042 | EAST CAROLINA PIRATES Diamond Head Classic | W 79-66 | 6-2 | J. Nicholson 26 | C. Phipps 8 | C. Phipps 14 |
| December 17, 2042 | ALABAMA CRIMSON TIDE Diamond Head Classic | L 72-84 | 6-3 | C. Phipps 24 | J. Richardson 3 | R. Prescott 7 |
| December 21, 2042 | @ Kansas State Wildcats | W 87-82 OT | 7-3 | R. Prescott 25 | J. Sims 5 | R. Prescott 13 |
| December 26, 2042 | @ Michigan State Spartans (7-3, 0-0, 4-0 Home)* | - | | | | |
| December 28, 2042 | @ Nebraska Cornhuskers (3-6, 0-0, 3-3 Home)* | - | | | | |
| January 2, 2043 | @ Northwestern Wildcats (5-6, 0-0, 2-3 Home)* | - | | | | |
| January 4, 2043 | UCLA BRUINS (5-5, 0-0, 0-1 Away)* | - | | | | |
| January 9, 2043 | INDIANA HOOSIERS (7-4, 0-0, 1-3 Away)* | - | | | | |
| January 11, 2043 | @ Michigan Wolverines (4-5, 0-0, 4-2 Home)* | - | | | | |
| January 16, 2043 | @ Illinois Fighting Illini (7-2, 0-0, 5-0 Home)* | - | | | | |
| January 18, 2043 | USC TROJANS (8-2, 0-0, 0-2 Away)* | - | | | | |
| January 23, 2043 | PENN STATE NITTANY LIONS (6-3, 0-0, 1-2 Away)* | - | | | | |
| January 25, 2043 | @ Washington Huskies (3-6, 0-0, 3-2 Home)* | - | | | | |
| January 30, 2043 | @ Purdue Boilermakers (10-1, 0-0, 7-1 Home)* | - | | | | |
| February 1, 2043 | OHIO STATE BUCKEYES (4-5, 0-0, 0-1 Away)* | - | | | | |
| February 6, 2043 | @ Wisconsin Badgers (5-4, 0-0, 5-2 Home)* | - | | | | |
| February 8, 2043 | RUTGERS SCARLET KNIGHTS (8-1, 0-0, 0-0 Away)* | - | | | | |
| February 13, 2043 | IOWA HAWKEYES (9-1, 0-0, 3-1 Away)* | - | | | | |
| February 15, 2043 | MINNESOTA GOLDEN GOPHERS (9-2, 0-0, 2-0 Away)* | - | | | | |
| February 20, 2043 | @ Oregon Ducks (4-5, 0-0, 4-2 Home)* | - | | | | |
| February 22, 2043 | @ UCLA Bruins (5-5, 0-0, 4-3 Home)* | - | | | | |
| February 27, 2043 | MICHIGAN WOLVERINES (4-5, 0-0, 0-2 Away)* | - | | | | |
| March 1, 2043 | OREGON DUCKS (4-5, 0-0, 0-2 Away)* | - | | | | |
