| November 16, 2042 | COLORADO STATE RAMS | W 79-66 | 1-0 | C. Phipps 21 | C. Phipps 6 | C. Phipps 10 |
| November 19, 2042 | CREIGHTON BLUE JAYS | W 83-67 | 2-0 | C. Phipps 21 | J. Sims 4 | C. Phipps 13 |
| November 23, 2042 | LOYOLA MARYMOUNT LIONS | W 78-55 | 3-0 | T. Nowak 23 | J. Richardson 7 | T. Nowak 11 |
| November 30, 2042 | @ #17 Miami (FL) Hurricanes | L 77-88 | 3-1 | C. Phipps 21 | C. Phipps 7 | J. Nicholson 9 |
| December 7, 2042 | SANTA CLARA BRONCOS | W 85-73 | 4-1 | J. Nicholson 21 | C. Phipps 7 | C. Phipps 10 |
| December 10, 2042 | #6 NOTRE DAME FIGHTING IRISH | W 89-86 | 5-1 | C. Phipps 25 | J. Richardson 5 | C. Phipps 7 |
| December 13, 2042 | @ #10 West Virginia Mountaineers | L 70-85 | 5-2 | C. Phipps 26 | J. Richardson 4 | T. Nowak 13 |
| December 16, 2042 | EAST CAROLINA PIRATES Diamond Head Classic | W 79-66 | 6-2 | J. Nicholson 26 | C. Phipps 8 | C. Phipps 14 |
| December 17, 2042 | ALABAMA CRIMSON TIDE Diamond Head Classic | L 72-84 | 6-3 | C. Phipps 24 | J. Richardson 3 | R. Prescott 7 |
| December 21, 2042 | @ Kansas State Wildcats | W 87-82 OT | 7-3 | R. Prescott 25 | J. Sims 5 | R. Prescott 13 |
| December 26, 2042 | @ Michigan State Spartans* | W 93-83 | 8-3 | C. Phipps 28 | C. Phipps 9 | C. Phipps 7 |
| December 28, 2042 | @ Nebraska Cornhuskers* | W 74-63 | 9-3 | C. Phipps 25 | D. Michell 4 | C. Phipps 12 |
| January 2, 2043 | @ Northwestern Wildcats* | W 57-55 | 10-3 | T. Nowak 14 | C. Phipps 5 | T. Nowak 13 |
| January 4, 2043 | UCLA BRUINS* | W 72-53 | 11-3 | J. Nicholson 17 | C. Phipps 7 | T. Nowak 15 |
| January 9, 2043 | INDIANA HOOSIERS* | W 87-67 | 12-3 | C. Phipps 23 | C. Phipps 6 | J. Nicholson 6 |
| January 11, 2043 | @ Michigan Wolverines* | L 83-84 | 12-4 | J. Nicholson 22 | D. Michell 5 | D. Anthony 8 |
| January 16, 2043 | @ Illinois Fighting Illini* | L 77-91 | 12-5 | C. Phipps 25 | D. Michell 6 | C. Phipps 6 |
| January 18, 2043 | USC TROJANS* | W 90-74 | 13-5 | T. Nowak 19 | C. Phipps 5 | C. Phipps 10 |
| January 23, 2043 | PENN STATE NITTANY LIONS* | L 68-86 | 13-6 | C. Phipps 22 | C. Phipps 7 | J. Nicholson 8 |
| January 25, 2043 | @ Washington Huskies* | W 88-75 | 14-6 | C. Phipps 26 | C. Phipps 8 | C. Phipps 9 |
| January 30, 2043 | @ #6 Purdue Boilermakers* | L 74-89 | 14-7 | C. Phipps 24 | J. Nicholson 5 | T. Nowak 9 |
| February 1, 2043 | OHIO STATE BUCKEYES* | W 89-52 | 15-7 | J. Nicholson 17 | J. Richardson 7 | J. Nicholson 11 |
| February 6, 2043 | @ Wisconsin Badgers* | W 83-80 | 16-7 | C. Phipps 27 | J. Nicholson 6 | J. Nicholson 8 |
| February 8, 2043 | RUTGERS SCARLET KNIGHTS* | L 76-80 | 16-8 | C. Phipps 21 | C. Phipps 6 | C. Phipps 10 |
| February 13, 2043 | IOWA HAWKEYES (18-7, 8-6, 6-4 Away)* | - | | | | |
| February 15, 2043 | MINNESOTA GOLDEN GOPHERS (21-4, 12-2, 7-1 Away)* | - | | | | |
| February 20, 2043 | @ Oregon Ducks (13-10, 9-5, 10-4 Home)* | - | | | | |
| February 22, 2043 | @ UCLA Bruins (9-15, 4-10, 7-7 Home)* | - | | | | |
| February 27, 2043 | MICHIGAN WOLVERINES (12-11, 8-6, 2-6 Away)* | - | | | | |
| March 1, 2043 | OREGON DUCKS (13-10, 9-5, 3-5 Away)* | - | | | | |
