| November 15, 2042 | @ Alabama Crimson Tide | L 60-102 | 0-1 | D. Caldwell 11 | L. Akers 3 | H. Perry 4 |
| November 22, 2042 | @ Holy Cross Crusaders | L 73-74 | 0-2 | D. Moya 16 | J. Calderon 5 | L. Akers 7 |
| November 25, 2042 | MAINE BLACK BEARS | W 80-73 | 1-2 | J. Calderon 17 | D. Moya 3 | J. Calderon 5 |
| November 29, 2042 | RICHMOND SPIDERS | W 81-54 | 2-2 | J. Calderon 19 | D. Moya 7 | D. Caldwell 10 |
| December 2, 2042 | DETROIT MERCY TITANS | L 71-72 | 2-3 | D. Moya 13 | D. Moya 3 | D. Caldwell 7 |
| December 6, 2042 | @ Texas A&M Aggies | L 69-74 | 2-4 | J. Calderon 23 | L. Akers 5 | L. Akers 6 |
| December 9, 2042 | @ Indiana Hoosiers Cayman Islands Classic | L 61-79 | 2-5 | H. Perry 12 | D. Moya 3 | L. Akers 9 |
| December 13, 2042 | NORTHERN KENTUCKY NORSE | W 78-50 | 3-5 | D. Moya 12 | L. Akers 4 | D. Carter 14 |
| December 15, 2042 | @ MD-Eastern Shore Hawks | L 65-79 | 3-6 | D. Moya 19 | J. Calderon 5 | L. Akers 6 |
| December 26, 2042 | KENT STATE GOLDEN FLASHES* | L 68-71 | 3-7 | J. Calderon 16 | D. Moya 4 | J. Calderon 6 |
| December 29, 2042 | BOWLING GREEN FALCONS* | W 67-62 | 4-7 | D. Carter 14 | D. Moya 6 | D. Moya 7 |
| January 2, 2043 | @ Eastern Michigan Eagles* | L 82-91 OT | 4-8 | H. Perry 20 | D. Moya 5 | J. Calderon 6 |
| January 5, 2043 | @ Toledo Rockets* | L 64-71 | 4-9 | J. Calderon 13 | D. Moya 6 | L. Akers 5 |
| January 9, 2043 | @ Akron Zips* | L 63-79 | 4-10 | J. Calderon 13 | D. Moya 4 | H. Perry 10 |
| January 12, 2043 | WESTERN MICHIGAN BRONCOS* | L 66-74 | 4-11 | L. Akers 11 | D. Moya 4 | D. Carter 10 |
| January 16, 2043 | @ Ball State Cardinals* | W 86-81 | 5-11 | J. Calderon 34 | D. Moya 9 | L. Akers 14 |
| January 19, 2043 | CENTRAL MICHIGAN CHIPPEWAS* | L 73-85 | 5-12 | J. Calderon 20 | D. Moya 4 | L. Akers 6 |
| January 23, 2043 | NORTHERN ILLINOIS HUSKIES* | W 76-64 | 6-12 | H. Perry 21 | D. Moya 5 | D. Moya 6 |
| January 26, 2043 | BALL STATE CARDINALS* | W 85-73 | 7-12 | H. Perry 16 | M. Hodge 4 | D. Caldwell 6 |
| January 30, 2043 | @ Central Michigan Chippewas* | L 62-72 | 7-13 | J. Calderon 27 | D. Moya 6 | L. Akers 8 |
| February 2, 2043 | @ Northern Illinois Huskies* | L 86-89 OT | 7-14 | L. Akers 16 | D. Moya 6 | L. Akers 7 |
| February 6, 2043 | @ Western Michigan Broncos* | L 75-80 | 7-15 | L. Akers 20 | D. Moya 4 | H. Perry 7 |
| February 9, 2043 | @ Buffalo Bulls* | L 71-81 | 7-16 | M. Hodge 14 | D. Moya 3 | H. Perry 7 |
| February 13, 2043 | EASTERN MICHIGAN EAGLES (13-10, 8-6, 5-6 Away)* | - | | | | |
| February 16, 2043 | TOLEDO ROCKETS (14-10, 9-5, 4-7 Away)* | - | | | | |
| February 20, 2043 | @ Kent State Golden Flashes (14-11, 8-6, 7-1 Home)* | - | | | | |
| February 23, 2043 | @ Bowling Green Falcons (9-14, 6-8, 7-4 Home)* | - | | | | |
| February 27, 2043 | BUFFALO BULLS (12-11, 8-6, 1-10 Away)* | - | | | | |
| March 2, 2043 | OHIO BOBCATS (12-12, 6-8, 1-9 Away)* | - | | | | |
