| November 13, 2038 | LA SALLE EXPLORERS Legends Classic | W 80-64 | 1-0 | N. Izzo 30 | A. Weaks 7 | N. Izzo 12 |
| November 15, 2038 | @ #8 Saint Mary's Gaels Legends Classic | W 81-69 | 2-0 | M. Deren 19 | A. Weaks 5 | N. Izzo 8 |
| November 17, 2038 | @ #4 Wichita State Shockers Legends Classic | W 76-67 | 3-0 | M. Deren 21 | A. Weaks 7 | N. Izzo 12 |
| November 19, 2038 | @ #6 Colorado Buffaloes Legends Classic | L 73-84 | 3-1 | R. Sheppard 14 | A. Weaks 3 | R. Sheppard 11 |
| November 22, 2038 | HAMPTON PIRATES | W 95-60 | 4-1 | N. Izzo 29 | A. Weaks 7 | N. Izzo 12 |
| November 25, 2038 | UAB BLAZERS | W 71-54 | 5-1 | R. Ruddock 16 | A. Weaks 9 | R. Hopkins 8 |
| November 29, 2038 | MARSHALL THUNDERING HERD | W 87-64 | 6-1 | M. Deren 21 | A. Weaks 11 | N. Izzo 9 |
| December 2, 2038 | CENTRAL MICHIGAN CHIPPEWAS | W 84-42 | 7-1 | R. Ruddock 14 | M. Genachowski 7 | R. Ruddock 10 |
| December 6, 2038 | BALL STATE CARDINALS | W 103-71 | 8-1 | R. Ruddock 26 | R. Hopkins 7 | R. Sheppard 9 |
| December 9, 2038 | UT ARLINGTON MAVERICKS | W 66-49 | 9-1 | N. Izzo 16 | A. Weaks 4 | N. Izzo 11 |
| December 13, 2038 | DUKE BLUE DEVILS | W 82-60 | 10-1 | A. Weaks 18 | R. Hopkins 5 | N. Izzo 9 |
| December 20, 2038 | UC SANTA BARBARA GAUCHOS | W 71-50 | 11-1 | N. Izzo 19 | M. Deren 3 | N. Izzo 13 |
| December 26, 2038 | #6 MARYLAND TERRAPINS* | W 77-61 | 12-1 | N. Izzo 18 | A. Weaks 5 | R. Ruddock 10 |
| December 28, 2038 | @ Illinois Fighting Illini* | W 88-71 | 13-1 | R. Ruddock 26 | A. Weaks 7 | R. Ruddock 10 |
| December 30, 2038 | @ Purdue Boilermakers* | L 63-66 | 13-2 | N. Izzo 19 | A. Weaks 6 | N. Izzo 11 |
| January 2, 2039 | NEBRASKA CORNHUSKERS* | W 71-56 | 14-2 | N. Izzo 24 | A. Weaks 4 | N. Izzo 12 |
| January 4, 2039 | RUTGERS SCARLET KNIGHTS* | W 85-67 | 15-2 | M. Deren 22 | A. Weaks 6 | N. Izzo 8 |
| January 9, 2039 | @ Penn State Nittany Lions* | W 69-58 | 16-2 | N. Izzo 20 | A. Weaks 3 | R. Ruddock 10 |
| January 13, 2039 | #14 MINNESOTA GOLDEN GOPHERS* | W 82-74 | 17-2 | M. Deren 15 | R. Hopkins 5 | R. Ruddock 11 |
| January 16, 2039 | @ Nebraska Cornhuskers (4-11, 1-5, 4-3 Home)* | - | | | | |
| January 20, 2039 | @ Wisconsin Badgers (10-4, 4-1, 9-2 Home)* | - | | | | |
| January 25, 2039 | NORTHWESTERN WILDCATS (7-6, 2-2, 2-4 Away)* | - | | | | |
| January 27, 2039 | PURDUE BOILERMAKERS (10-6, 3-4, 1-4 Away)* | - | | | | |
| February 1, 2039 | @ Indiana Hoosiers (5-10, 3-3, 5-5 Home)* | - | | | | |
| February 3, 2039 | OHIO STATE BUCKEYES (9-5, 2-3, 2-1 Away)* | - | | | | |
| February 6, 2039 | @ Iowa Hawkeyes (9-5, 2-3, 7-2 Home)* | - | | | | |
| February 10, 2039 | MICHIGAN STATE SPARTANS (5-10, 2-4, 0-6 Away)* | - | | | | |
| February 13, 2039 | WISCONSIN BADGERS (10-4, 4-1, 1-2 Away)* | - | | | | |
| February 17, 2039 | @ Rutgers Scarlet Knights (9-6, 4-2, 8-2 Home)* | - | | | | |
| February 24, 2039 | @ Ohio State Buckeyes (9-5, 2-3, 7-4 Home)* | - | | | | |
| March 1, 2039 | INDIANA HOOSIERS (5-10, 3-3, 0-5 Away)* | - | | | | |
| March 3, 2039 | @ Northwestern Wildcats (7-6, 2-2, 5-2 Home)* | - | | | | |
