| November 14, 2042 | SAN DIEGO STATE AZTECS NIT Season Tip-Off | L 66-81 | 0-1 | R. Daniels 15 | A. Blanchard 4 | K. Moore 6 |
| November 23, 2042 | VILLANOVA WILDCATS | L 75-84 | 0-2 | R. Daniels 17 | R. Daniels 4 | T. Patten 11 |
| November 26, 2042 | @ Iowa State Cyclones | L 72-88 | 0-3 | H. Nash 10 | B. Smiley 5 | B. Smiley 7 |
| November 30, 2042 | @ #2 Kansas Jayhawks | L 58-76 | 0-4 | R. Bryant 16 | C. Jones 5 | B. Smiley 11 |
| December 3, 2042 | ALABAMA CRIMSON TIDE | W 85-79 | 1-4 | R. Daniels 18 | C. Jones 5 | B. Smiley 6 |
| December 7, 2042 | CHARLOTTE 49ERS | W 96-61 | 2-4 | C. Jones 15 | C. Jones 6 | D. Fitzgerald 7 |
| December 10, 2042 | BYU COUGARS | L 77-82 | 2-5 | R. Bryant 25 | B. Smiley 5 | B. Smiley 9 |
| December 13, 2042 | DUKE BLUE DEVILS | W 84-82 | 3-5 | T. Patten 17 | R. Bryant 5 | T. Patten 10 |
| December 21, 2042 | GEORGIA SOUTHERN EAGLES | W 78-71 | 4-5 | H. Nash 21 | C. Jones 5 | D. Fitzgerald 9 |
| December 26, 2042 | #22 IOWA HAWKEYES* | L 65-86 | 4-6 | K. Moore 10 | C. Jones 3 | H. Nash 8 |
| December 28, 2042 | WISCONSIN BADGERS* | W 90-70 | 5-6 | H. Nash 18 | R. Bryant 6 | T. Patten 9 |
| January 2, 2043 | WASHINGTON HUSKIES* | W 86-61 | 6-6 | D. Fitzgerald 21 | A. Blanchard 7 | D. Fitzgerald 11 |
| January 4, 2043 | ILLINOIS FIGHTING ILLINI* | W 86-81 | 7-6 | A. Blanchard 20 | R. Bryant 5 | A. Blanchard 7 |
| January 9, 2043 | @ Penn State Nittany Lions* | L 56-88 | 7-7 | D. Fitzgerald 14 | R. Bryant 3 | D. Fitzgerald 8 |
| January 11, 2043 | #10 MARYLAND TERRAPINS* | W 84-83 | 8-7 | H. Nash 15 | R. Bryant 7 | H. Nash 7 |
| January 16, 2043 | @ Northwestern Wildcats* | L 70-75 | 8-8 | R. Daniels 22 | H. Nash 3 | T. Patten 10 |
| January 18, 2043 | @ #4 Purdue Boilermakers* | W 69-64 | 9-8 | A. Blanchard 15 | A. Blanchard 3 | H. Nash 7 |
| January 23, 2043 | OREGON DUCKS* | L 73-81 | 9-9 | R. Daniels 18 | B. Smiley 4 | B. Smiley 9 |
| January 25, 2043 | UCLA BRUINS* | W 79-67 | 10-9 | A. Blanchard 17 | R. Bryant 3 | D. Fitzgerald 9 |
| January 30, 2043 | @ #5 Minnesota Golden Gophers* | L 67-81 | 10-10 | A. Blanchard 14 | R. Bryant 3 | D. Fitzgerald 9 |
| February 1, 2043 | INDIANA HOOSIERS* | W 82-79 | 11-10 | D. Fitzgerald 16 | C. Jones 4 | B. Smiley 12 |
| February 6, 2043 | @ Nebraska Cornhuskers* | W 77-52 | 12-10 | R. Bryant 20 | R. Bryant 7 | T. Patten 10 |
| February 8, 2043 | @ Michigan State Spartans* | L 67-70 | 12-11 | R. Bryant 13 | R. Bryant 2 | T. Patten 13 |
| February 13, 2043 | @ Rutgers Scarlet Knights* | W 77-67 | 13-11 | A. Blanchard 22 | C. Jones 7 | D. Fitzgerald 13 |
| February 15, 2043 | USC TROJANS* | L 84-109 | 13-12 | A. Blanchard 18 | B. Smiley 4 | D. Fitzgerald 9 |
| February 20, 2043 | @ Ohio State Buckeyes* | W 73-63 | 14-12 | R. Daniels 13 | R. Bryant 3 | D. Fitzgerald 9 |
| February 22, 2043 | MICHIGAN STATE SPARTANS* | L 66-76 | 14-13 | R. Daniels 17 | B. Smiley 4 | K. Moore 7 |
| February 27, 2043 | @ #23 Maryland Terrapins* | L 66-78 | 14-14 | A. Blanchard 15 | C. Jones 4 | K. Moore 11 |
| March 1, 2043 | @ Indiana Hoosiers* | W 107-99 OT | 15-14 | A. Blanchard 35 | B. Smiley 6 | B. Smiley 11 |
| March 8, 2043 | NORTHWESTERN WILDCATS Big 10 Tournament | W 79-62 | 16-14 | A. Blanchard 22 | B. Smiley 5 | B. Smiley 8 |
| March 9, 2043 | @ Illinois Fighting Illini Big 10 Tournament | L 71-75 | 16-15 | T. Patten 17 | B. Smiley 5 | D. Fitzgerald 8 |
| March 14, 2043 | STONY BROOK SEAWOLVES NIT Tournament | W 69-54 | 17-15 | B. Smiley 14 | R. Bryant 3 | B. Smiley 11 |
| March 16, 2043 | @ SMU Mustangs NIT Tournament | W 76-74 | 18-15 | R. Daniels 25 | R. Daniels 4 | D. Fitzgerald 9 |
| March 21, 2043 | @ Rhode Island Rams NIT Tournament | L 60-67 | 18-16 | R. Daniels 18 | C. Jones 4 | D. Fitzgerald 9 |
