| November 16, 2042 | @ Marquette Golden Eagles | L 58-73 | 0-1 | D. Applegate 14 | D. Applegate 4 | D. Applegate 6 |
| November 19, 2042 | @ Bucknell Bison | L 69-80 | 0-2 | H. Meadows 27 | T. Naismith 3 | S. Johnstone 7 |
| November 23, 2042 | @ Cornell Big Red | L 74-102 | 0-3 | D. Applegate 20 | H. Meadows 5 | H. Meadows 4 |
| November 26, 2042 | JAMES MADISON DUKES | W 81-67 | 1-3 | H. Meadows 22 | H. Meadows 4 | T. Scott 8 |
| November 30, 2042 | LIBERTY FLAMES | L 62-82 | 1-4 | D. Applegate 24 | D. Cooper 4 | T. Scott 7 |
| December 3, 2042 | @ San Diego Toreros | W 70-67 | 2-4 | H. Meadows 20 | T. Naismith 5 | T. Scott 9 |
| December 7, 2042 | @ North Carolina Central Eagles | L 60-62 | 2-5 | G. Watson 18 | D. Applegate 3 | T. Scott 14 |
| December 10, 2042 | WESTERN ILLINOIS LEATHERNECKS | W 81-77 | 3-5 | H. Meadows 18 | D. Applegate 3 | H. Meadows 7 |
| December 13, 2042 | NIAGARA PURPLE EAGLES | L 83-88 | 3-6 | H. Meadows 33 | D. Applegate 7 | T. Naismith 6 |
| December 17, 2042 | BINGHAMTON BEARCATS | W 80-68 | 4-6 | J. West 20 | T. Naismith 5 | T. Naismith 7 |
| December 21, 2042 | @ Rice Owls | L 67-85 | 4-7 | D. Applegate 23 | D. Applegate 3 | S. Johnstone 7 |
| December 24, 2042 | @ North Alabama Lions | L 56-65 | 4-8 | H. Meadows 14 | D. Applegate 4 | T. Scott 5 |
| December 28, 2042 | @ Montana State Bobcats | L 72-86 | 4-9 | H. Meadows 24 | D. Applegate 4 | T. Scott 8 |
| January 7, 2043 | @ North Dakota St. Bison* | L 60-80 | 4-10 | D. Applegate 15 | T. Naismith 5 | T. Scott 9 |
| January 11, 2043 | ORAL ROBERTS GOLDEN EAGLES* | L 62-72 | 4-11 | T. Scott 15 | D. Applegate 4 | T. Naismith 8 |
| January 14, 2043 | @ Omaha Mavericks* | L 49-70 | 4-12 | D. Applegate 22 | H. Meadows 4 | T. Scott 9 |
| January 18, 2043 | SOUTH DAKOTA STATE JACKRABBITS* | L 81-83 | 4-13 | T. Naismith 17 | D. Applegate 6 | T. Naismith 5 |
| January 21, 2043 | @ Denver Pioneers* | W 80-76 | 5-13 | G. Watson 15 | D. Applegate 5 | D. Applegate 6 |
| January 25, 2043 | NORTH DAKOTA FIGHTING HAWKS* | W 74-56 | 6-13 | H. Meadows 17 | D. Applegate 5 | T. Naismith 7 |
| January 28, 2043 | @ South Dakota Coyotes* | L 69-86 | 6-14 | D. Applegate 16 | S. Johnstone 4 | T. Scott 8 |
| February 1, 2043 | ST. THOMAS TOMMIES* | L 70-82 | 6-15 | H. Meadows 19 | D. Applegate 4 | T. Naismith 6 |
| February 8, 2043 | NORTH DAKOTA ST. BISON* | W 73-71 | 7-15 | D. Applegate 23 | D. Applegate 5 | R. Robinson 7 |
| February 11, 2043 | @ Oral Roberts Golden Eagles* | W 79-71 | 8-15 | D. Applegate 23 | S. Johnstone 5 | T. Naismith 8 |
| February 15, 2043 | OMAHA MAVERICKS (14-10, 8-3, 4-10 Away)* | - | | | | |
| February 18, 2043 | @ South Dakota State Jackrabbits (12-12, 5-6, 7-5 Home)* | - | | | | |
| February 22, 2043 | DENVER PIONEERS (8-15, 4-6, 1-12 Away)* | - | | | | |
| February 25, 2043 | @ North Dakota Fighting Hawks (9-15, 4-7, 5-3 Home)* | - | | | | |
| March 1, 2043 | SOUTH DAKOTA COYOTES (12-12, 5-6, 3-8 Away)* | - | | | | |
| March 4, 2043 | @ St. Thomas Tommies (17-7, 8-3, 10-2 Home)* | - | | | | |
