| November 13, 2042 | SOUTH CAROLINA STATE BULLDOGS | L 100-101 OT | 0-1 | C. Henderson 30 | A. Newton 8 | H. Smiley 10 |
| November 14, 2042 | @ Norfolk State Spartans | W 91-83 | 1-1 | C. Henderson 25 | A. Newton 4 | H. Smiley 8 |
| November 22, 2042 | @ Southern Jaguars | W 96-95 | 2-1 | B. Shipp 25 | A. Newton 5 | C. Henderson 9 |
| November 25, 2042 | @ Army Black Knights | L 82-102 | 2-2 | C. Henderson 25 | A. Newton 7 | C. Henderson 5 |
| November 29, 2042 | @ Marist Red Foxes | W 99-81 | 3-2 | B. Shipp 21 | A. Newton 7 | P. Butler 7 |
| December 6, 2042 | @ Loyola Chicago Ramblers | L 72-80 | 3-3 | B. Shipp 23 | A. Newton 4 | B. Shipp 9 |
| December 9, 2042 | @ Wisconsin Badgers Baha Mar Hoops Bahamas Championship | W 90-74 | 4-3 | C. Henderson 27 | B. McIntyre 2 | H. Smiley 14 |
| December 10, 2042 | GEORGIA SOUTHERN EAGLES Baha Mar Hoops Bahamas Championship | L 58-80 | 4-4 | P. Butler 12 | A. Newton 4 | C. Henderson 9 |
| December 13, 2042 | @ Little Rock Trojans | W 99-79 | 5-4 | P. Butler 25 | A. Newton 11 | H. Smiley 10 |
| December 20, 2042 | @ Texas Southern Tigers | L 82-104 | 5-5 | J. Capel 16 | A. Newton 4 | H. Smiley 8 |
| December 26, 2042 | @ UIC Flames* | L 79-82 | 5-6 | B. Shipp 15 | A. Newton 8 | J. Capel 11 |
| December 29, 2042 | @ Northern Iowa Panthers* | W 101-85 | 6-6 | C. Henderson 26 | A. Newton 7 | C. Henderson 10 |
| January 2, 2043 | BELMONT BRUINS* | L 78-81 | 6-7 | C. Henderson 17 | A. Newton 6 | H. Smiley 7 |
| January 5, 2043 | ILLINOIS STATE REDBIRDS* | L 83-91 | 6-8 | C. Henderson 28 | A. Newton 8 | C. Henderson 11 |
| January 9, 2043 | EVANSVILLE PURPLE ACES* | L 71-74 | 6-9 | C. Henderson 15 | A. Newton 6 | H. Smiley 13 |
| January 12, 2043 | @ Murray State Racers* | L 90-97 OT | 6-10 | C. Henderson 19 | P. Butler 8 | C. Henderson 10 |
| January 16, 2043 | VALPARAISO CRUSADERS* | W 97-79 | 7-10 | C. Henderson 19 | A. Newton 6 | H. Smiley 11 |
| January 19, 2043 | @ Bradley Braves* | L 59-71 | 7-11 | C. Henderson 14 | A. Newton 5 | H. Smiley 10 |
| January 23, 2043 | @ Southern Illinois Salukis* | L 61-67 | 7-12 | A. Newton 18 | A. Newton 4 | H. Smiley 11 |
| January 26, 2043 | @ Valparaiso Crusaders* | W 89-73 | 8-12 | C. Henderson 20 | A. Newton 7 | B. Shipp 9 |
| January 30, 2043 | BRADLEY BRAVES* | W 79-75 | 9-12 | P. Butler 22 | B. Shipp 3 | A. Newton 8 |
| February 2, 2043 | SOUTHERN ILLINOIS SALUKIS* | L 72-87 | 9-13 | A. Newton 12 | A. Newton 7 | H. Smiley 9 |
| February 6, 2043 | MURRAY STATE RACERS* | L 82-87 | 9-14 | C. Henderson 21 | B. McIntyre 5 | B. Shipp 9 |
| February 9, 2043 | @ Indiana State Sycamores* | L 74-84 | 9-15 | H. Smiley 21 | B. McIntyre 4 | H. Smiley 11 |
| February 13, 2043 | @ Belmont Bruins* | L 64-94 | 9-16 | B. Shipp 13 | A. Newton 7 | B. Shipp 9 |
| February 16, 2043 | @ Illinois State Redbirds* | W 89-82 | 10-16 | P. Butler 17 | A. Newton 7 | H. Smiley 10 |
| February 20, 2043 | UIC FLAMES* | W 88-76 | 11-16 | P. Butler 19 | A. Newton 10 | J. Capel 14 |
| February 23, 2043 | INDIANA STATE SYCAMORES* | L 77-89 | 11-17 | J. Capel 19 | A. Newton 4 | J. Capel 13 |
| February 27, 2043 | NORTHERN IOWA PANTHERS* | W 89-86 | 12-17 | P. Butler 22 | A. Newton 7 | H. Smiley 11 |
| March 2, 2043 | @ Drake Bulldogs* | W 81-77 | 13-17 | P. Butler 20 | A. Newton 5 | H. Smiley 6 |
| March 6, 2043 | DRAKE BULLDOGS MVC Tournament | W 74-72 | 14-17 | C. Henderson 21 | P. Butler 3 | H. Smiley 11 |
| March 7, 2043 | @ Murray State Racers MVC Tournament | W 77-76 | 15-17 | C. Henderson 24 | P. Butler 6 | B. Shipp 9 |
| March 8, 2043 | @ Evansville Purple Aces MVC Tournament | W 92-81 | 16-17 | P. Butler 20 | A. Newton 4 | C. Henderson 12 |
| March 9, 2043 | @ Illinois State Redbirds MVC Tournament | W 82-71 | 17-17 | P. Butler 17 | A. Newton 4 | H. Smiley 16 |
| March 14, 2043 | ABILENE CHRISTIAN WILDCATS NCAA Tournament | W 85-78 | 18-17 | J. Capel 15 | P. Butler 4 | J. Capel 8 |
| March 16, 2043 | @ #1 North Carolina Tar Heels NCAA Tournament | L 67-91 | 18-18 | P. Butler 18 | A. Newton 5 | H. Smiley 11 |
