| November 14, 2042 | @ #12 VCU Rams NIT Season Tip-Off | L 73-89 | 0-1 | B. Spears 14 | J. Hatcher 4 | B. Spears 12 |
| November 22, 2042 | @ UT Rio Grande Valley Vaqueros | W 100-66 | 1-1 | J. Hatcher 24 | W. Simmons 5 | T. Taylor 9 |
| November 25, 2042 | LEHIGH MOUNTAIN HAWKS | W 85-73 | 2-1 | W. Simmons 22 | J. Hatcher 5 | T. Taylor 11 |
| November 30, 2042 | @ #18 Louisville Cardinals | L 63-77 | 2-2 | W. Simmons 13 | J. Hatcher 7 | W. Simmons 8 |
| December 2, 2042 | BRYANT BULLDOGS | W 90-67 | 3-2 | D. Branch 34 | J. Hatcher 6 | W. Simmons 6 |
| December 6, 2042 | @ Tennessee State Tigers | W 93-78 | 4-2 | J. Hatcher 19 | J. Hatcher 4 | W. Simmons 10 |
| December 9, 2042 | COPPIN STATE EAGLES | W 88-73 | 5-2 | D. Branch 25 | D. Branch 7 | T. Taylor 9 |
| December 13, 2042 | SAINT LOUIS BILLIKENS | W 86-69 | 6-2 | J. Hatcher 17 | A. Espinoza 6 | W. Simmons 6 |
| December 20, 2042 | @ Northern Colorado Bears | W 92-82 | 7-2 | T. Taylor 16 | J. Meier 4 | W. Simmons 11 |
| December 26, 2042 | BRADLEY BRAVES* | L 69-82 | 7-3 | A. Espinoza 12 | J. Meier 5 | A. Espinoza 6 |
| December 29, 2042 | SOUTHERN ILLINOIS SALUKIS* | L 59-78 | 7-4 | J. Hatcher 15 | J. Hatcher 5 | W. Simmons 10 |
| January 2, 2043 | @ UIC Flames* | L 81-92 | 7-5 | W. Simmons 16 | D. Branch 3 | R. Spivey 4 |
| January 5, 2043 | @ Northern Iowa Panthers* | W 88-67 | 8-5 | T. Taylor 18 | J. Hatcher 5 | T. Taylor 8 |
| January 9, 2043 | @ Belmont Bruins* | W 79-59 | 9-5 | T. Taylor 12 | J. Meier 5 | W. Simmons 8 |
| January 12, 2043 | MISSOURI STATE BEARS* | W 97-90 OT | 10-5 | R. Spivey 18 | J. Meier 7 | W. Simmons 10 |
| January 16, 2043 | @ Indiana State Sycamores* | L 70-87 | 10-6 | R. Spivey 16 | J. Hatcher 3 | W. Simmons 11 |
| January 19, 2043 | EVANSVILLE PURPLE ACES* | W 92-84 | 11-6 | B. Spears 15 | J. Meier 5 | W. Simmons 10 |
| January 23, 2043 | DRAKE BULLDOGS* | W 82-63 | 12-6 | R. Andersen 19 | J. Hatcher 9 | W. Simmons 10 |
| January 26, 2043 | INDIANA STATE SYCAMORES* | W 88-58 | 13-6 | J. Hatcher 18 | J. Hatcher 5 | D. Sanders 9 |
| January 30, 2043 | @ Evansville Purple Aces* | L 76-85 | 13-7 | D. Branch 17 | R. Andersen 6 | W. Simmons 12 |
| February 2, 2043 | @ Drake Bulldogs* | W 84-77 | 14-7 | J. Hatcher 18 | J. Hatcher 6 | T. Taylor 9 |
| February 6, 2043 | @ Missouri State Bears* | W 87-82 | 15-7 | W. Simmons 14 | J. Hatcher 6 | W. Simmons 9 |
| February 9, 2043 | @ Valparaiso Crusaders* | W 88-76 | 16-7 | W. Simmons 24 | W. Simmons 6 | W. Simmons 8 |
| February 13, 2043 | UIC FLAMES (11-12, 8-6, 6-3 Away)* | - | | | | |
| February 16, 2043 | NORTHERN IOWA PANTHERS (8-15, 5-9, 4-6 Away)* | - | | | | |
| February 20, 2043 | @ Bradley Braves (11-12, 7-7, 7-6 Home)* | - | | | | |
| February 23, 2043 | @ Southern Illinois Salukis (11-12, 7-7, 8-6 Home)* | - | | | | |
| February 27, 2043 | VALPARAISO CRUSADERS (11-12, 5-9, 4-7 Away)* | - | | | | |
| March 2, 2043 | ILLINOIS STATE REDBIRDS (10-13, 7-7, 3-9 Away)* | - | | | | |
