| November 14, 2042 | @ Canisius Golden Griffins | L 69-90 | 0-1 | E. Kirklin 16 | J. Samuel 3 | J. Evans 7 |
| November 17, 2042 | @ LIU Sharks | L 45-66 | 0-2 | E. Kirklin 9 | J. Evans 4 | E. Kirklin 5 |
| November 21, 2042 | @ Incarnate Word Cardinals | L 68-78 | 0-3 | E. Nolan 19 | D. Hayden 3 | J. Evans 7 |
| November 24, 2042 | @ Furman Paladins | L 57-77 | 0-4 | E. Kirklin 13 | C. Beaudean 3 | J. Samuel 8 |
| November 28, 2042 | BALL STATE CARDINALS | L 63-75 | 0-5 | E. Nolan 18 | C. Beaudean 9 | J. Evans 7 |
| December 1, 2042 | @ Air Force Falcons | W 81-80 | 1-5 | E. Nolan 15 | C. Beaudean 5 | J. Samuel 8 |
| December 5, 2042 | TEXAS SOUTHERN TIGERS | L 83-93 | 1-6 | J. Evans 19 | C. Beaudean 8 | J. Samuel 6 |
| December 8, 2042 | CENTRAL ARKANSAS BEARS | L 71-72 | 1-7 | E. Nolan 16 | C. Beaudean 7 | C. Beaudean 8 |
| December 13, 2042 | MD-EASTERN SHORE HAWKS | W 77-60 | 2-7 | J. Evans 23 | C. Beaudean 9 | J. Evans 8 |
| December 19, 2042 | @ Delaware Fightin' Blue Hens | L 63-71 | 2-8 | E. Nolan 15 | C. Beaudean 5 | C. Beaudean 9 |
| December 27, 2042 | @ UMass Minutemen | L 60-81 | 2-9 | E. Nolan 21 | C. Beaudean 2 | E. Nolan 7 |
| January 2, 2043 | @ Bucknell Bison* | W 78-72 | 3-9 | J. Evans 24 | C. Beaudean 5 | J. Evans 12 |
| January 5, 2043 | AMERICAN EAGLES* | W 86-76 | 4-9 | J. Evans 19 | C. Beaudean 5 | J. Evans 9 |
| January 9, 2043 | @ Colgate Raiders* | L 74-91 | 4-10 | C. Beaudean 17 | E. Nolan 3 | J. Evans 11 |
| January 12, 2043 | HOLY CROSS CRUSADERS* | L 60-72 | 4-11 | E. Nolan 13 | C. Beaudean 4 | J. Evans 6 |
| January 16, 2043 | @ Army Black Knights* | L 71-85 | 4-12 | E. Kirklin 16 | C. Beaudean 5 | C. Beaudean 4 |
| January 19, 2043 | LAFAYETTE LEOPARDS* | W 84-75 | 5-12 | E. Nolan 22 | C. Beaudean 7 | E. Nolan 5 |
| January 23, 2043 | @ Boston University Terriers* | L 73-83 | 5-13 | E. Nolan 28 | C. Beaudean 6 | D. Hayden 6 |
| January 26, 2043 | LOYOLA MARYLAND GREYHOUNDS* | L 64-69 | 5-14 | E. Nolan 26 | C. Beaudean 3 | J. Evans 6 |
| January 30, 2043 | @ Lehigh Mountain Hawks* | W 73-63 | 6-14 | E. Nolan 14 | C. Beaudean 6 | T. Lopes 9 |
| February 2, 2043 | BUCKNELL BISON* | L 64-65 | 6-15 | E. Nolan 12 | T. Lopes 4 | C. Beaudean 12 |
| February 6, 2043 | @ American Eagles* | L 72-93 | 6-16 | E. Nolan 15 | C. Beaudean 4 | C. Beaudean 9 |
| February 9, 2043 | COLGATE RAIDERS* | W 69-65 | 7-16 | J. Evans 14 | J. Evans 4 | C. Beaudean 7 |
| February 13, 2043 | @ Holy Cross Crusaders* | W 73-72 | 8-16 | E. Nolan 25 | C. Beaudean 10 | J. Evans 6 |
| February 16, 2043 | ARMY BLACK KNIGHTS* | L 54-77 | 8-17 | J. Evans 10 | C. Beaudean 3 | J. Evans 7 |
| February 20, 2043 | @ Lafayette Leopards* | L 57-68 | 8-18 | E. Nolan 21 | C. Beaudean 5 | E. Nolan 7 |
| February 23, 2043 | BOSTON UNIVERSITY TERRIERS* | W 81-80 | 9-18 | J. Evans 17 | C. Beaudean 7 | J. Samuel 5 |
| February 27, 2043 | @ Loyola Maryland Greyhounds* | W 70-57 | 10-18 | E. Nolan 22 | C. Beaudean 7 | J. Evans 8 |
| March 2, 2043 | LEHIGH MOUNTAIN HAWKS* | W 85-72 | 11-18 | C. Beaudean 20 | E. Nolan 3 | E. Kirklin 9 |
| March 6, 2043 | @ Bucknell Bison Patriot League Tournament | L 58-62 | 11-19 | J. Samuel 13 | C. Beaudean 5 | D. Hayden 7 |
