| November 14, 2042 | HAWAI'I RAINBOW WARRIORS NIT Season Tip-Off | W 79-63 | 1-0 | S. Estrada 15 | S. Estrada 4 | E. Bullock 8 |
| November 16, 2042 | #15 KENTUCKY WILDCATS NIT Season Tip-Off | W 79-64 | 2-0 | S. Estrada 18 | M. Decker 5 | D. Attaway 8 |
| November 18, 2042 | #6 WICHITA STATE SHOCKERS NIT Season Tip-Off | W 88-72 | 3-0 | S. Cesnik 16 | S. Estrada 5 | E. Bullock 7 |
| November 20, 2042 | @ #1 Baylor Bears NIT Season Tip-Off | W 87-78 | 4-0 | A. Voss 16 | E. Bullock 5 | E. Bullock 10 |
| November 23, 2042 | #18 UTAH STATE AGGIES | L 79-90 | 4-1 | S. Cesnik 23 | S. Estrada 5 | E. Bullock 9 |
| November 26, 2042 | DAVIDSON WILDCATS | W 73-70 | 5-1 | S. Estrada 22 | M. Decker 6 | E. Bullock 8 |
| November 30, 2042 | SOUTH CAROLINA GAMECOCKS | W 77-60 | 6-1 | A. Mosley 14 | S. Estrada 7 | A. Voss 7 |
| December 3, 2042 | @ #5 Minnesota Golden Gophers | L 72-75 | 6-2 | S. Estrada 19 | M. Decker 7 | E. Bullock 11 |
| December 7, 2042 | #14 SAINT MARY'S GAELS | W 101-68 | 7-2 | S. Estrada 29 | M. Decker 9 | A. Voss 8 |
| December 10, 2042 | @ #17 Maryland Terrapins | L 86-89 | 7-3 | S. Estrada 25 | M. Decker 6 | E. Bullock 9 |
| December 13, 2042 | @ USC Trojans | L 97-103 | 7-4 | S. Estrada 30 | M. Decker 8 | D. Attaway 7 |
| December 21, 2042 | DAYTON FLYERS | W 95-64 | 8-4 | E. Bullock 17 | M. Decker 5 | E. Bullock 14 |
| December 26, 2042 | @ NC State Wolfpack* | W 75-62 | 9-4 | S. Estrada 24 | M. Decker 7 | N. Trilli 11 |
| December 28, 2042 | VIRGINIA CAVALIERS* | W 84-64 | 10-4 | S. Estrada 20 | E. Bullock 5 | E. Bullock 12 |
| January 2, 2043 | @ Georgia Tech Yellow Jackets* | W 104-81 | 11-4 | E. Bullock 24 | M. Decker 8 | E. Bullock 11 |
| January 4, 2043 | @ #13 Louisville Cardinals* | L 84-86 | 11-5 | M. Decker 15 | M. Decker 5 | A. Voss 7 |
| January 9, 2043 | @ #24 Florida State Seminoles* | W 76-61 | 12-5 | S. Cesnik 18 | M. Decker 8 | S. Cesnik 5 |
| January 11, 2043 | @ #6 Stanford Cardinal* | L 82-85 | 12-6 | S. Estrada 16 | S. Estrada 7 | N. Trilli 9 |
| January 16, 2043 | SYRACUSE ORANGE* | W 86-75 | 13-6 | N. Trilli 17 | S. Estrada 7 | N. Trilli 8 |
| January 18, 2043 | @ Virginia Tech Hokies* | W 89-78 | 14-6 | S. Cesnik 25 | M. Decker 7 | N. Trilli 10 |
| January 23, 2043 | @ Miami (FL) Hurricanes* | L 75-79 | 14-7 | S. Estrada 20 | M. Decker 5 | A. Voss 11 |
| January 25, 2043 | SMU MUSTANGS* | W 101-86 | 15-7 | S. Estrada 25 | M. Decker 7 | N. Trilli 10 |
| January 30, 2043 | BOSTON COLLEGE EAGLES* | W 82-70 | 16-7 | S. Cesnik 32 | M. Decker 6 | N. Trilli 12 |
| February 1, 2043 | PITTSBURGH PANTHERS* | W 87-74 | 17-7 | S. Estrada 18 | M. Decker 6 | N. Trilli 10 |
| February 6, 2043 | @ Wake Forest Demon Deacons* | W 88-72 | 18-7 | S. Cesnik 20 | M. Decker 6 | E. Bullock 8 |
| February 8, 2043 | DUKE BLUE DEVILS* | W 98-67 | 19-7 | S. Cesnik 20 | M. Decker 9 | N. Trilli 9 |
| February 13, 2043 | NORTH CAROLINA TAR HEELS (24-1, 14-0, 9-1 Away)* | - | | | | |
| February 15, 2043 | @ California Golden Bears (7-16, 6-8, 7-6 Home)* | - | | | | |
| February 20, 2043 | CLEMSON TIGERS (7-16, 5-9, 3-8 Away)* | - | | | | |
| February 22, 2043 | @ Clemson Tigers (7-16, 5-9, 4-7 Home)* | - | | | | |
| February 27, 2043 | LOUISVILLE CARDINALS (15-10, 6-8, 4-5 Away)* | - | | | | |
| March 1, 2043 | GEORGIA TECH YELLOW JACKETS (16-9, 8-6, 4-6 Away)* | - | | | | |
