| November 13, 2042 | @ Ohio Bobcats Legends Classic | L 62-78 | 0-1 | A. Herbert 15 | S. Jaramillo 5 | A. Herbert 10 |
| November 22, 2042 | @ VCU Rams | L 68-105 | 0-2 | L. Masters 12 | J. Spangler 3 | T. Heath 5 |
| November 26, 2042 | DARTMOUTH BIG GREEN | W 80-76 | 1-2 | D. Caldwell 15 | S. Jaramillo 3 | L. Masters 7 |
| November 29, 2042 | @ Missouri Tigers | L 69-93 | 1-3 | L. Masters 17 | S. Jaramillo 3 | K. Marsh 7 |
| December 2, 2042 | @ Ball State Cardinals | W 83-79 | 2-3 | S. Jaramillo 27 | S. Jaramillo 6 | J. Spangler 6 |
| December 7, 2042 | CAMPBELL CAMELS | W 77-69 | 3-3 | K. Marsh 18 | D. Caldwell 6 | K. Marsh 6 |
| December 13, 2042 | SOUTH DAKOTA COYOTES | L 74-77 | 3-4 | K. Marsh 17 | S. Jaramillo 3 | K. Marsh 5 |
| December 17, 2042 | @ North Dakota St. Bison | L 72-76 | 3-5 | K. Marsh 12 | S. Jaramillo 4 | L. Masters 10 |
| December 21, 2042 | ORAL ROBERTS GOLDEN EAGLES | L 88-94 | 3-6 | J. Spangler 23 | R. Dunlap 4 | L. Masters 8 |
| December 26, 2042 | INDIANA STATE SYCAMORES* | L 50-71 | 3-7 | S. Jaramillo 7 | S. Jaramillo 3 | A. Herbert 8 |
| December 29, 2042 | MISSOURI STATE BEARS* | L 85-101 | 3-8 | K. Marsh 19 | R. Dunlap 3 | K. Marsh 8 |
| January 2, 2043 | VALPARAISO CRUSADERS* | W 92-78 | 4-8 | D. Caldwell 13 | S. Jaramillo 5 | L. Masters 11 |
| January 5, 2043 | MURRAY STATE RACERS* | L 67-88 | 4-9 | L. Masters 14 | R. Dunlap 4 | A. Herbert 8 |
| January 9, 2043 | @ Southern Illinois Salukis* | W 83-75 | 5-9 | S. Jaramillo 29 | S. Jaramillo 4 | K. Marsh 8 |
| January 12, 2043 | @ Drake Bulldogs* | L 65-72 | 5-10 | K. Marsh 13 | K. Marsh 5 | K. Marsh 7 |
| January 16, 2043 | @ Evansville Purple Aces* | L 74-90 | 5-11 | D. Caldwell 12 | S. Jaramillo 7 | A. Herbert 7 |
| January 19, 2043 | ILLINOIS STATE REDBIRDS* | W 79-61 | 6-11 | A. Herbert 12 | S. Jaramillo 6 | L. Masters 9 |
| January 23, 2043 | BELMONT BRUINS* | L 66-83 | 6-12 | J. Spangler 16 | S. Jaramillo 7 | A. Herbert 8 |
| January 26, 2043 | @ UIC Flames* | W 81-74 | 7-12 | K. Marsh 20 | S. Jaramillo 7 | A. Herbert 9 |
| January 30, 2043 | @ Illinois State Redbirds* | L 73-87 | 7-13 | K. Marsh 14 | S. Jaramillo 5 | L. Masters 8 |
| February 2, 2043 | @ Belmont Bruins* | W 94-89 | 8-13 | J. Spangler 17 | S. Jaramillo 5 | K. Marsh 7 |
| February 6, 2043 | DRAKE BULLDOGS* | L 64-69 | 8-14 | J. Spangler 10 | K. Marsh 3 | K. Marsh 9 |
| February 9, 2043 | EVANSVILLE PURPLE ACES* | L 80-84 | 8-15 | S. Jaramillo 18 | S. Jaramillo 7 | L. Masters 9 |
| February 13, 2043 | @ Valparaiso Crusaders* | L 61-72 | 8-16 | A. Herbert 13 | S. Jaramillo 8 | L. Masters 11 |
| February 16, 2043 | @ Murray State Racers* | L 57-87 | 8-17 | A. Herbert 8 | S. Jaramillo 2 | R. Dunlap 7 |
| February 20, 2043 | @ Indiana State Sycamores (21-6, 13-3, 10-1 Home)* | - | | | | |
| February 23, 2043 | UIC FLAMES (11-14, 8-8, 6-5 Away)* | - | | | | |
| February 27, 2043 | @ Missouri State Bears (10-16, 5-11, 2-6 Home)* | - | | | | |
| March 2, 2043 | BRADLEY BRAVES (12-13, 8-8, 5-7 Away)* | - | | | | |
