| November 14, 2042 | VIRGINIA CAVALIERS | W 81-58 | 1-0 | T. Murray 19 | I. Adams 8 | T. Murray 15 |
| November 21, 2042 | TULANE GREEN WAVE | W 95-66 | 2-0 | T. Murray 24 | I. Adams 8 | C. Helliwell 11 |
| November 24, 2042 | VERMONT CATAMOUNTS | W 100-55 | 3-0 | M. Croom 17 | N. Medrano 6 | C. Helliwell 9 |
| November 28, 2042 | SIU EDWARDSVILLE COUGARS | W 94-83 | 4-0 | W. Minor 21 | I. Adams 7 | C. Helliwell 11 |
| December 1, 2042 | ALABAMA A&M BULLDOGS | W 98-62 | 5-0 | N. Medrano 22 | J. Riddle 9 | C. Helliwell 10 |
| December 5, 2042 | OREGON STATE BEAVERS | W 83-69 | 6-0 | I. Adams 25 | I. Adams 6 | C. Helliwell 10 |
| December 13, 2042 | OKLAHOMA SOONERS | W 86-77 | 7-0 | T. Murray 25 | M. Croom 6 | T. Murray 5 |
| December 16, 2042 | LOYOLA CHICAGO RAMBLERS Vegas Showdown | W 79-66 | 8-0 | I. Adams 17 | M. Croom 6 | C. Helliwell 12 |
| December 17, 2042 | COLORADO STATE RAMS Vegas Showdown | W 80-59 | 9-0 | T. Murray 19 | I. Adams 4 | C. Helliwell 12 |
| December 18, 2042 | #7 PURDUE BOILERMAKERS Vegas Showdown | L 86-92 | 9-1 | I. Adams 25 | I. Adams 4 | C. Helliwell 9 |
| December 19, 2042 | EAST CAROLINA PIRATES | W 64-57 | 10-1 | T. Murray 12 | I. Adams 5 | T. Murray 13 |
| December 26, 2042 | @ Houston Cougars (7-2, 0-0, 7-0 Home)* | - | | | | |
| December 30, 2042 | CINCINNATI BEARCATS (8-2, 0-0, 0-0 Away)* | - | | | | |
| January 4, 2043 | @ Colorado Buffaloes (6-4, 0-0, 4-2 Home)* | - | | | | |
| January 6, 2043 | UCF KNIGHTS (5-4, 0-0, 0-3 Away)* | - | | | | |
| January 11, 2043 | @ Kansas State Wildcats (5-5, 0-0, 2-4 Home)* | - | | | | |
| January 13, 2043 | IOWA STATE CYCLONES (2-7, 0-0, 0-2 Away)* | - | | | | |
| January 18, 2043 | BYU COUGARS (7-3, 0-0, 1-2 Away)* | - | | | | |
| January 20, 2043 | @ Kansas Jayhawks (10-1, 0-0, 6-0 Home)* | - | | | | |
| January 25, 2043 | @ Utah Utes (7-4, 0-0, 5-3 Home)* | - | | | | |
| January 30, 2043 | TCU HORNED FROGS (7-3, 0-0, 0-2 Away)* | - | | | | |
| February 1, 2043 | @ West Virginia Mountaineers (9-2, 0-0, 6-1 Home)* | - | | | | |
| February 3, 2043 | KANSAS JAYHAWKS (10-1, 0-0, 1-1 Away)* | - | | | | |
| February 8, 2043 | UTAH UTES (7-4, 0-0, 0-0 Away)* | - | | | | |
| February 10, 2043 | @ Texas Tech Red Raiders (6-4, 0-0, 4-1 Home)* | - | | | | |
| February 15, 2043 | @ TCU Horned Frogs (7-3, 0-0, 6-0 Home)* | - | | | | |
| February 17, 2043 | ARIZONA STATE SUN DEVILS (7-3, 0-0, 1-0 Away)* | - | | | | |
| February 22, 2043 | COLORADO BUFFALOES (6-4, 0-0, 1-1 Away)* | - | | | | |
| February 24, 2043 | @ Baylor Bears (11-1, 0-0, 7-0 Home)* | - | | | | |
| March 1, 2043 | HOUSTON COUGARS (7-2, 0-0, 0-2 Away)* | - | | | | |
| March 3, 2043 | @ Arizona Wildcats (3-6, 0-0, 3-2 Home)* | - | | | | |
