| November 14, 2042 | VIRGINIA CAVALIERS | W 81-58 | 1-0 | T. Murray 19 | I. Adams 8 | T. Murray 15 |
| November 21, 2042 | TULANE GREEN WAVE | W 95-66 | 2-0 | T. Murray 24 | I. Adams 8 | C. Helliwell 11 |
| November 24, 2042 | VERMONT CATAMOUNTS | W 100-55 | 3-0 | M. Croom 17 | N. Medrano 6 | C. Helliwell 9 |
| November 28, 2042 | SIU EDWARDSVILLE COUGARS | W 94-83 | 4-0 | W. Minor 21 | I. Adams 7 | C. Helliwell 11 |
| December 1, 2042 | ALABAMA A&M BULLDOGS | W 98-62 | 5-0 | N. Medrano 22 | J. Riddle 9 | C. Helliwell 10 |
| December 5, 2042 | OREGON STATE BEAVERS | W 83-69 | 6-0 | I. Adams 25 | I. Adams 6 | C. Helliwell 10 |
| December 13, 2042 | OKLAHOMA SOONERS | W 86-77 | 7-0 | T. Murray 25 | M. Croom 6 | T. Murray 5 |
| December 16, 2042 | LOYOLA CHICAGO RAMBLERS Vegas Showdown | W 79-66 | 8-0 | I. Adams 17 | M. Croom 6 | C. Helliwell 12 |
| December 17, 2042 | COLORADO STATE RAMS Vegas Showdown | W 80-59 | 9-0 | T. Murray 19 | I. Adams 4 | C. Helliwell 12 |
| December 18, 2042 | #7 PURDUE BOILERMAKERS Vegas Showdown | L 86-92 | 9-1 | I. Adams 25 | I. Adams 4 | C. Helliwell 9 |
| December 19, 2042 | EAST CAROLINA PIRATES | W 64-57 | 10-1 | T. Murray 12 | I. Adams 5 | T. Murray 13 |
| December 26, 2042 | @ Houston Cougars* | L 73-89 | 10-2 | C. Helliwell 16 | I. Adams 9 | T. Murray 9 |
| December 30, 2042 | CINCINNATI BEARCATS* | W 88-58 | 11-2 | M. Croom 17 | I. Adams 6 | C. Helliwell 10 |
| January 4, 2043 | @ Colorado Buffaloes* | W 79-72 | 12-2 | M. Croom 12 | I. Adams 4 | T. Murray 13 |
| January 6, 2043 | UCF KNIGHTS* | L 92-101 | 12-3 | N. Medrano 15 | I. Adams 4 | C. Helliwell 5 |
| January 11, 2043 | @ Kansas State Wildcats* | W 79-70 | 13-3 | C. Helliwell 17 | I. Adams 5 | C. Helliwell 9 |
| January 13, 2043 | IOWA STATE CYCLONES* | W 78-69 | 14-3 | I. Adams 14 | I. Adams 3 | W. Minor 10 |
| January 18, 2043 | BYU COUGARS* | W 87-69 | 15-3 | M. Croom 17 | I. Adams 6 | W. Minor 9 |
| January 20, 2043 | @ #3 Kansas Jayhawks* | L 68-81 | 15-4 | M. Croom 16 | I. Adams 5 | T. Murray 8 |
| January 25, 2043 | @ Utah Utes* | L 79-82 | 15-5 | N. Medrano 16 | I. Adams 5 | I. Adams 7 |
| January 30, 2043 | TCU HORNED FROGS* | L 89-97 | 15-6 | M. Croom 23 | I. Adams 7 | C. Helliwell 10 |
| February 1, 2043 | @ #13 West Virginia Mountaineers* | L 68-93 | 15-7 | T. Murray 19 | I. Adams 6 | T. Murray 9 |
| February 3, 2043 | #4 KANSAS JAYHAWKS* | L 74-75 | 15-8 | I. Adams 17 | M. Croom 5 | C. Helliwell 11 |
| February 8, 2043 | UTAH UTES* | L 70-77 | 15-9 | M. Croom 14 | I. Adams 4 | W. Minor 6 |
| February 10, 2043 | @ Texas Tech Red Raiders* | L 68-78 | 15-10 | W. Minor 15 | M. Croom 4 | C. Helliwell 7 |
| February 15, 2043 | @ TCU Horned Frogs (15-9, 8-6, 11-2 Home)* | - | | | | |
| February 17, 2043 | ARIZONA STATE SUN DEVILS (15-9, 8-6, 4-4 Away)* | - | | | | |
| February 22, 2043 | COLORADO BUFFALOES (13-11, 7-7, 4-5 Away)* | - | | | | |
| February 24, 2043 | @ Baylor Bears (23-3, 12-2, 13-1 Home)* | - | | | | |
| March 1, 2043 | HOUSTON COUGARS (16-7, 9-5, 4-5 Away)* | - | | | | |
| March 3, 2043 | @ Arizona Wildcats (5-18, 2-12, 5-7 Home)* | - | | | | |
