| November 16, 2042 | UT MARTIN SKYHAWKS | W 99-69 | 1-0 | J. Ledesma 19 | R. Darnell 6 | R. Bledsoe 9 |
| November 18, 2042 | SEATTLE REDHAWKS Allstate Maui Invitational | L 78-83 | 1-1 | R. Darnell 19 | R. Darnell 6 | D. Perez 6 |
| November 22, 2042 | DAYTON FLYERS | W 99-83 | 2-1 | R. Darnell 21 | R. Darnell 6 | D. Perez 11 |
| November 26, 2042 | @ #15 Louisville Cardinals | L 78-94 | 2-2 | R. Darnell 19 | R. Darnell 5 | D. Perez 10 |
| November 30, 2042 | @ George Washington Colonials | W 111-87 | 3-2 | R. Darnell 19 | E. Mistry 6 | D. Perez 12 |
| December 3, 2042 | @ #16 Florida State Seminoles | L 64-72 | 3-3 | R. Darnell 13 | R. Darnell 2 | D. Perez 12 |
| December 7, 2042 | CENTRAL MICHIGAN CHIPPEWAS | W 87-72 | 4-3 | J. Ledesma 25 | R. Darnell 5 | R. Bledsoe 11 |
| December 10, 2042 | MEMPHIS TIGERS | W 83-64 | 5-3 | J. Ledesma 18 | E. Mistry 5 | D. Perez 10 |
| December 13, 2042 | PITTSBURGH PANTHERS | W 88-75 | 6-3 | R. Darnell 23 | R. Darnell 3 | R. Bledsoe 10 |
| December 26, 2042 | @ Oregon Ducks (4-5, 0-0, 4-2 Home)* | - | | | | |
| December 28, 2042 | @ Indiana Hoosiers (7-4, 0-0, 3-1 Home)* | - | | | | |
| January 2, 2043 | PURDUE BOILERMAKERS (10-1, 0-0, 0-0 Away)* | - | | | | |
| January 4, 2043 | @ Nebraska Cornhuskers (3-6, 0-0, 3-3 Home)* | - | | | | |
| January 9, 2043 | MICHIGAN WOLVERINES (4-5, 0-0, 0-2 Away)* | - | | | | |
| January 11, 2043 | MICHIGAN STATE SPARTANS (7-3, 0-0, 1-3 Away)* | - | | | | |
| January 16, 2043 | IOWA HAWKEYES (9-1, 0-0, 3-1 Away)* | - | | | | |
| January 18, 2043 | ILLINOIS FIGHTING ILLINI (7-2, 0-0, 2-2 Away)* | - | | | | |
| January 23, 2043 | @ Maryland Terrapins (7-3, 0-0, 5-0 Home)* | - | | | | |
| January 25, 2043 | @ USC Trojans (8-2, 0-0, 6-0 Home)* | - | | | | |
| January 30, 2043 | WASHINGTON HUSKIES (3-6, 0-0, 0-3 Away)* | - | | | | |
| February 1, 2043 | @ Rutgers Scarlet Knights (8-1, 0-0, 8-0 Home)* | - | | | | |
| February 6, 2043 | @ Ohio State Buckeyes (4-5, 0-0, 4-3 Home)* | - | | | | |
| February 8, 2043 | @ UCLA Bruins (5-5, 0-0, 4-3 Home)* | - | | | | |
| February 13, 2043 | @ Wisconsin Badgers (5-4, 0-0, 5-2 Home)* | - | | | | |
| February 15, 2043 | NORTHWESTERN WILDCATS (5-6, 0-0, 1-2 Away)* | - | | | | |
| February 20, 2043 | MINNESOTA GOLDEN GOPHERS (9-2, 0-0, 2-0 Away)* | - | | | | |
| February 22, 2043 | NEBRASKA CORNHUSKERS (3-6, 0-0, 0-2 Away)* | - | | | | |
| February 27, 2043 | WISCONSIN BADGERS (5-4, 0-0, 0-1 Away)* | - | | | | |
| March 1, 2043 | @ Northwestern Wildcats (5-6, 0-0, 2-3 Home)* | - | | | | |
