| November 15, 2039 |  LAMAR CARDINALS | W 79-59 | 1-0 | D. Drew 18 | A. Barr 6 | S. Dooling 8 |
| November 17, 2039 |  @ #10 VCU Rams | L 64-83 | 1-1 | A. Holmes 10 | S. Dooling 4 | A. Barr 6 |
| November 22, 2039 |  @ #19 Kentucky Wildcats | L 38-84 | 1-2 | A. Barr 7 | D. Gentry 3 | A. Holmes 6 |
| November 24, 2039 |  NJIT HIGHLANDERS | L 79-88 | 1-3 | A. Holmes 15 | S. Bond 4 | S. Dooling 7 |
| November 30, 2039 |  NORTHERN ARIZONA LUMBERJACKS | W 69-50 | 2-3 | D. Gentry 15 | J. Mickens 5 | A. Holmes 13 |
| December 2, 2039 |  COLUMBIA LIONS | W 74-58 | 3-3 | D. Gentry 22 | S. Driver 5 | S. Dooling 9 |
| December 5, 2039 |  SIU EDWARDSVILLE COUGARS | L 79-80 | 3-4 | D. Drew 21 | D. Gentry 9 | S. Dooling 8 |
| December 9, 2039 |  CHARLESTON COUGARS  Jimmy V Classic | L 74-75 | 3-5 | A. Holmes 22 | D. Gentry 5 | A. Holmes 11 |
| December 13, 2039 |  @ #23 Rhode Island Rams | L 74-78 | 3-6 | D. Drew 16 | D. Gentry 3 | A. Barr 7 |
| December 26, 2039 |  @ #17 Connecticut Huskies* | L 60-76 | 3-7 | A. Holmes 14 | D. Gentry 6 | A. Holmes 11 |
| December 30, 2039 |  DEPAUL BLUE DEMONS* | W 79-63 | 4-7 | A. Holmes 13 | D. Gentry 5 | S. Dooling 10 |
| January 2, 2040 |  @ Marquette Golden Eagles* | L 77-86 | 4-8 | A. Holmes 13 | S. Dooling 4 | S. Dooling 9 |
| January 4, 2040 |  GEORGETOWN HOYAS* | L 51-70 | 4-9 | D. Drew 14 | D. Gentry 3 | S. Dooling 11 |
| January 6, 2040 |  BUTLER BULLDOGS* | W 80-64 | 5-9 | A. Holmes 20 | A. Holmes 5 | A. Holmes 7 |
| January 11, 2040 |  @ #18 Xavier Musketeers* | L 64-89 | 5-10 | S. Dooling 13 | D. Gentry 3 | A. Holmes 8 |
| January 13, 2040 |  @ Seton Hall Pirates* | L 61-103 | 5-11 | S. Dooling 11 | D. Gentry 3 | A. Holmes 6 |
| January 18, 2040 |  ST. JOHN'S RED STORM* | W 88-64 | 6-11 | A. Holmes 24 | S. Driver 6 | A. Holmes 15 |
| January 23, 2040 | @ #12 Georgetown Hoyas* | L 53-79 | 6-12 | A. Holmes 12 | S. Dooling 3 | A. Holmes 10 |
| January 27, 2040 |  CREIGHTON BLUE JAYS* | W 98-76 | 7-12 | D. Gentry 19 | D. Gentry 7 | S. Dooling 5 |
| January 30, 2040 |  VILLANOVA WILDCATS* | L 81-96 | 7-13 | A. Holmes 19 | D. Gentry 11 | M. Fast 7 |
| February 1, 2040 | @ Butler Bulldogs* | L 73-79 | 7-14 | D. Gentry 14 | D. Gentry 4 | S. Driver 6 |
| February 3, 2040 | @ DePaul Blue Demons* | L 44-69 | 7-15 | S. Dooling 14 | S. Bond 3 | A. Holmes 9 |
| February 8, 2040 | #25 SETON HALL PIRATES* | L 54-73 | 7-16 | D. Gentry 9 | D. Gentry 5 | S. Dooling 9 |
| February 10, 2040 | #20 XAVIER MUSKETEERS* | L 68-84 | 7-17 | D. Gentry 12 | D. Gentry 3 | A. Holmes 5 |
| February 15, 2040 | @ Creighton Blue Jays* | L 53-81 | 7-18 | S. Dooling 9 | S. Dooling 4 | S. Dooling 5 |
| February 17, 2040 | @ Villanova Wildcats* | L 62-84 | 7-19 | J. Mickens 12 | D. Gentry 4 | A. Holmes 9 |
| February 22, 2040 | MARQUETTE GOLDEN EAGLES* | L 76-82 | 7-20 | S. Dooling 19 | D. Drew 9 | S. Dooling 7 |
| February 24, 2040 | CONNECTICUT HUSKIES* | W 77-67 | 8-20 | D. Gentry 25 | D. Drew 6 | A. Holmes 11 |
| March 3, 2040 | @ St. John's Red Storm* | L 81-87 OT | 8-21 | A. Barr 19 | D. Gentry 7 | S. Dooling 8 |
| March 9, 2040 | @ DePaul Blue Demons  Big East Tournament | L 42-65 | 8-22 | D. Drew 7 | D. Gentry 2 | S. Dooling 10 |
