| November 16, 2042 | MISSOURI TIGERS | W 71-66 | 1-0 | P. Quintanilla 19 | D. Garrett 5 | P. Quintanilla 14 |
| November 19, 2042 | WOFFORD TERRIERS | W 86-75 | 2-0 | P. Quintanilla 26 | D. Garrett 7 | P. Quintanilla 12 |
| November 22, 2042 | SAINT LOUIS BILLIKENS | L 72-77 | 2-1 | D. Garrett 20 | D. Garrett 5 | I. Markoulides 12 |
| November 26, 2042 | TROY TROJANS | W 91-77 | 3-1 | P. Quintanilla 27 | W. Crowley 8 | P. Quintanilla 11 |
| November 30, 2042 | STEPHEN F. AUSTIN LUMBERJACKS | W 94-63 | 4-1 | W. Crowley 28 | D. Garrett 14 | I. Markoulides 11 |
| December 7, 2042 | SMU MUSTANGS | W 79-71 | 5-1 | D. Garrett 19 | D. Garrett 5 | P. Quintanilla 11 |
| December 13, 2042 | BUTLER BULLDOGS | W 71-63 | 6-1 | P. Quintanilla 18 | P. Quintanilla 3 | E. Quinteros 12 |
| December 16, 2042 | TROY TROJANS Vegas Showdown | W 97-84 | 7-1 | P. Quintanilla 35 | D. Garrett 10 | P. Quintanilla 15 |
| December 17, 2042 | SOUTH FLORIDA BULLS Vegas Showdown | W 85-75 | 8-1 | P. Quintanilla 25 | D. Garrett 8 | P. Quintanilla 11 |
| December 18, 2042 | @ #18 Oklahoma State Cowboys Vegas Showdown | W 92-86 | 9-1 | P. Quintanilla 25 | D. Garrett 7 | P. Quintanilla 8 |
| December 21, 2042 | NEW MEXICO LOBOS | W 78-64 | 10-1 | P. Quintanilla 21 | D. Garrett 8 | E. Quinteros 13 |
| December 26, 2042 | RUTGERS SCARLET KNIGHTS (8-1, 0-0, 0-0 Away)* | - | | | | |
| December 28, 2042 | OHIO STATE BUCKEYES (4-5, 0-0, 0-1 Away)* | - | | | | |
| January 2, 2043 | @ Penn State Nittany Lions (6-3, 0-0, 5-0 Home)* | - | | | | |
| January 4, 2043 | @ Iowa Hawkeyes (9-1, 0-0, 4-0 Home)* | - | | | | |
| January 9, 2043 | USC TROJANS (8-2, 0-0, 0-2 Away)* | - | | | | |
| January 11, 2043 | @ Washington Huskies (3-6, 0-0, 3-2 Home)* | - | | | | |
| January 16, 2043 | @ Indiana Hoosiers (7-4, 0-0, 3-1 Home)* | - | | | | |
| January 18, 2043 | MICHIGAN WOLVERINES (4-5, 0-0, 0-2 Away)* | - | | | | |
| January 23, 2043 | @ Michigan State Spartans (7-3, 0-0, 4-0 Home)* | - | | | | |
| January 25, 2043 | MINNESOTA GOLDEN GOPHERS (9-2, 0-0, 2-0 Away)* | - | | | | |
| January 30, 2043 | MARYLAND TERRAPINS (7-3, 0-0, 1-2 Away)* | - | | | | |
| February 1, 2043 | @ Northwestern Wildcats (5-6, 0-0, 2-3 Home)* | - | | | | |
| February 6, 2043 | @ UCLA Bruins (5-5, 0-0, 4-3 Home)* | - | | | | |
| February 8, 2043 | @ Nebraska Cornhuskers (3-6, 0-0, 3-3 Home)* | - | | | | |
| February 13, 2043 | OREGON DUCKS (4-5, 0-0, 0-2 Away)* | - | | | | |
| February 15, 2043 | WISCONSIN BADGERS (5-4, 0-0, 0-1 Away)* | - | | | | |
| February 20, 2043 | ILLINOIS FIGHTING ILLINI (7-2, 0-0, 2-2 Away)* | - | | | | |
| February 22, 2043 | @ Rutgers Scarlet Knights (8-1, 0-0, 8-0 Home)* | - | | | | |
| February 27, 2043 | @ Ohio State Buckeyes (4-5, 0-0, 4-3 Home)* | - | | | | |
| March 1, 2043 | IOWA HAWKEYES (9-1, 0-0, 3-1 Away)* | - | | | | |
