| November 16, 2042 | MISSOURI TIGERS | W 71-66 | 1-0 | P. Quintanilla 19 | D. Garrett 5 | P. Quintanilla 14 |
| November 19, 2042 | WOFFORD TERRIERS | W 86-75 | 2-0 | P. Quintanilla 26 | D. Garrett 7 | P. Quintanilla 12 |
| November 22, 2042 | SAINT LOUIS BILLIKENS | L 72-77 | 2-1 | D. Garrett 20 | D. Garrett 5 | I. Markoulides 12 |
| November 26, 2042 | TROY TROJANS | W 91-77 | 3-1 | P. Quintanilla 27 | W. Crowley 8 | P. Quintanilla 11 |
| November 30, 2042 | STEPHEN F. AUSTIN LUMBERJACKS | W 94-63 | 4-1 | W. Crowley 28 | D. Garrett 14 | I. Markoulides 11 |
| December 7, 2042 | SMU MUSTANGS | W 79-71 | 5-1 | D. Garrett 19 | D. Garrett 5 | P. Quintanilla 11 |
| December 13, 2042 | BUTLER BULLDOGS | W 71-63 | 6-1 | P. Quintanilla 18 | P. Quintanilla 3 | E. Quinteros 12 |
| December 16, 2042 | TROY TROJANS Vegas Showdown | W 97-84 | 7-1 | P. Quintanilla 35 | D. Garrett 10 | P. Quintanilla 15 |
| December 17, 2042 | SOUTH FLORIDA BULLS Vegas Showdown | W 85-75 | 8-1 | P. Quintanilla 25 | D. Garrett 8 | P. Quintanilla 11 |
| December 18, 2042 | @ #18 Oklahoma State Cowboys Vegas Showdown | W 92-86 | 9-1 | P. Quintanilla 25 | D. Garrett 7 | P. Quintanilla 8 |
| December 21, 2042 | NEW MEXICO LOBOS | W 78-64 | 10-1 | P. Quintanilla 21 | D. Garrett 8 | E. Quinteros 13 |
| December 26, 2042 | RUTGERS SCARLET KNIGHTS* | W 91-65 | 11-1 | P. Quintanilla 20 | D. Garrett 6 | E. Quinteros 13 |
| December 28, 2042 | OHIO STATE BUCKEYES* | W 92-57 | 12-1 | P. Quintanilla 21 | D. Garrett 8 | E. Quinteros 12 |
| January 2, 2043 | @ Penn State Nittany Lions* | L 84-93 | 12-2 | P. Quintanilla 28 | D. Garrett 6 | I. Markoulides 12 |
| January 4, 2043 | @ #19 Iowa Hawkeyes* | L 57-73 | 12-3 | P. Quintanilla 19 | D. Garrett 5 | P. Quintanilla 13 |
| January 9, 2043 | USC TROJANS* | W 92-70 | 13-3 | I. Markoulides 26 | D. Garrett 13 | P. Quintanilla 15 |
| January 11, 2043 | @ Washington Huskies* | W 71-57 | 14-3 | E. Quinteros 20 | D. Garrett 7 | I. Markoulides 15 |
| January 16, 2043 | @ Indiana Hoosiers* | L 65-70 | 14-4 | P. Quintanilla 25 | D. Garrett 6 | P. Quintanilla 14 |
| January 18, 2043 | MICHIGAN WOLVERINES* | L 64-69 | 14-5 | P. Quintanilla 20 | D. Garrett 7 | E. Quinteros 10 |
| January 23, 2043 | @ Michigan State Spartans* | L 80-91 | 14-6 | P. Quintanilla 26 | D. Garrett 7 | P. Quintanilla 13 |
| January 25, 2043 | #5 MINNESOTA GOLDEN GOPHERS* | W 85-69 | 15-6 | P. Quintanilla 28 | D. Garrett 5 | I. Markoulides 13 |
| January 30, 2043 | #11 MARYLAND TERRAPINS* | W 89-74 | 16-6 | P. Quintanilla 29 | D. Garrett 5 | E. Quinteros 8 |
| February 1, 2043 | @ Northwestern Wildcats* | L 71-76 | 16-7 | W. Crowley 17 | D. Garrett 4 | E. Quinteros 11 |
| February 6, 2043 | @ UCLA Bruins* | W 91-68 | 17-7 | P. Quintanilla 20 | D. Garrett 7 | P. Quintanilla 13 |
| February 8, 2043 | @ Nebraska Cornhuskers* | W 92-80 | 18-7 | P. Quintanilla 32 | D. Garrett 13 | P. Quintanilla 13 |
| February 13, 2043 | OREGON DUCKS (13-10, 9-5, 3-5 Away)* | - | | | | |
| February 15, 2043 | WISCONSIN BADGERS (11-12, 6-8, 0-8 Away)* | - | | | | |
| February 20, 2043 | ILLINOIS FIGHTING ILLINI (16-7, 9-5, 4-6 Away)* | - | | | | |
| February 22, 2043 | @ Rutgers Scarlet Knights (11-12, 3-11, 10-3 Home)* | - | | | | |
| February 27, 2043 | @ Ohio State Buckeyes (6-17, 2-12, 6-8 Home)* | - | | | | |
| March 1, 2043 | IOWA HAWKEYES (18-7, 8-6, 6-4 Away)* | - | | | | |
