| November 15, 2042 | @ Cal St. Northridge Matadors | W 83-75 | 1-0 | S. Whittfield 14 | S. Whittfield 5 | S. Parker 9 |
| November 18, 2042 | @ Tulane Green Wave | L 62-83 | 1-1 | S. Whittfield 19 | M. Newton 4 | S. Whittfield 5 |
| November 22, 2042 | @ Stephen F. Austin Lumberjacks | L 66-93 | 1-2 | S. Whittfield 17 | S. Whittfield 6 | S. Parker 9 |
| November 25, 2042 | @ Southern Indiana Screaming Eagles | L 76-92 | 1-3 | S. Whittfield 16 | S. Whittfield 5 | M. Bekale 9 |
| November 29, 2042 | @ Illinois State Redbirds | L 56-71 | 1-4 | M. Newton 14 | S. Whittfield 3 | S. Whittfield 5 |
| December 2, 2042 | @ Merrimack Warriors | L 74-81 | 1-5 | S. Gipson 18 | S. Whittfield 5 | S. Parker 10 |
| December 6, 2042 | @ UC Riverside Highlanders | L 72-83 | 1-6 | M. Newton 21 | S. Whittfield 4 | M. Newton 10 |
| December 9, 2042 | TOWSON TIGERS | L 69-75 | 1-7 | S. Gipson 10 | S. Parker 5 | M. Newton 9 |
| December 13, 2042 | @ East Tennessee State Buccaneers | W 68-59 | 2-7 | M. Newton 14 | S. Whittfield 5 | M. Bekale 7 |
| December 16, 2042 | LOYOLA MARYLAND GREYHOUNDS | W 66-54 | 3-7 | M. Bekale 15 | S. Whittfield 5 | M. Newton 6 |
| December 20, 2042 | @ UAB Blazers | L 71-76 | 3-8 | K. Kearney 13 | S. Whittfield 6 | N. Hollingsworth 8 |
| December 23, 2042 | @ Fairfield Stags | W 78-76 | 4-8 | S. Whittfield 17 | S. Gipson 6 | S. Parker 6 |
| December 27, 2042 | @ Hampton Pirates | L 55-78 | 4-9 | S. Whittfield 19 | S. Gipson 4 | S. Parker 7 |
| January 3, 2043 | @ South Carolina Upstate Spartans* | L 74-77 | 4-10 | M. Newton 23 | S. Whittfield 3 | S. Parker 7 |
| January 6, 2043 | LONGWOOD LANCERS* | W 72-64 | 5-10 | S. Whittfield 18 | S. Whittfield 4 | S. Parker 10 |
| January 10, 2043 | @ Charleston Southern Buccaneers* | L 69-85 | 5-11 | S. Whittfield 18 | S. Whittfield 3 | M. Bekale 5 |
| January 13, 2043 | GARDNER-WEBB RUNNIN' BULLDOGS* | L 73-80 | 5-12 | M. Newton 15 | S. Whittfield 8 | M. Newton 8 |
| January 20, 2043 | @ High Point Panthers* | L 75-87 | 5-13 | M. Bekale 17 | S. Whittfield 8 | S. Parker 6 |
| January 24, 2043 | UNC ASHEVILLE BULLDOGS* | L 91-94 | 5-14 | S. Parker 19 | S. Whittfield 3 | M. Newton 6 |
| January 27, 2043 | @ Winthrop Eagles* | L 65-87 | 5-15 | M. Newton 13 | S. Whittfield 4 | M. Newton 9 |
| January 31, 2043 | PRESBYTERIAN BLUE HOSE* | L 60-68 | 5-16 | M. Newton 16 | S. Whittfield 3 | N. Hollingsworth 6 |
| February 3, 2043 | SOUTH CAROLINA UPSTATE SPARTANS* | W 82-65 | 6-16 | M. Bekale 24 | S. Whittfield 8 | S. Parker 11 |
| February 7, 2043 | @ Longwood Lancers* | L 74-92 | 6-17 | S. Whittfield 17 | S. Whittfield 4 | S. Parker 7 |
| February 10, 2043 | CHARLESTON SOUTHERN BUCCANEERS* | W 92-89 | 7-17 | S. Gipson 19 | S. Gipson 5 | N. Hollingsworth 7 |
| February 14, 2043 | @ Gardner-Webb Runnin' Bulldogs* | W 83-82 | 8-17 | M. Bekale 19 | D. Slater 4 | M. Bekale 11 |
| February 21, 2043 | HIGH POINT PANTHERS* | L 70-86 | 8-18 | S. Whittfield 13 | S. Whittfield 4 | M. Newton 16 |
| February 24, 2043 | @ UNC Asheville Bulldogs* | W 96-84 | 9-18 | M. Newton 17 | S. Whittfield 7 | M. Newton 7 |
| February 28, 2043 | WINTHROP EAGLES* | L 68-86 | 9-19 | S. Parker 17 | S. Whittfield 5 | S. Parker 10 |
| March 3, 2043 | @ Presbyterian Blue Hose* | L 77-79 | 9-20 | M. Newton 12 | M. Newton 4 | L. Stephens 9 |
| March 5, 2043 | LONGWOOD LANCERS Big South Tournament | L 68-80 | 9-21 | S. Whittfield 18 | S. Whittfield 4 | L. Stephens 7 |
