| November 16, 2042 | MICHIGAN STATE SPARTANS | W 82-52 | 1-0 | T. Clark 19 | T. Guzman 5 | A. Blakes 9 |
| November 18, 2042 | CLEVELAND STATE VIKINGS | L 64-65 | 1-1 | T. Guzman 17 | A. Blakes 6 | A. Blakes 11 |
| November 21, 2042 | ST. JOHN'S RED STORM Hall of Fame Classic | L 65-79 | 1-2 | M. Sweet 12 | T. Guzman 3 | A. Blakes 8 |
| November 25, 2042 | CENTRAL CONNECTICUT BLUE DEVILS | W 77-60 | 2-2 | T. Clark 19 | J. Oates 5 | P. Gregg 8 |
| November 30, 2042 | @ #4 Notre Dame Fighting Irish | L 60-77 | 2-3 | P. Gregg 11 | T. Guzman 3 | T. Clark 10 |
| December 2, 2042 | LIPSCOMB BISONS | L 86-99 | 2-4 | T. Guzman 22 | T. Guzman 5 | M. Sweet 5 |
| December 7, 2042 | @ Iowa Hawkeyes | L 66-75 | 2-5 | T. Guzman 18 | J. Ellis 5 | M. Sweet 8 |
| December 9, 2042 | HOUSTON CHRISTIAN HUSKIES | W 79-70 | 3-5 | J. Ellis 17 | T. Guzman 4 | T. Clark 12 |
| December 13, 2042 | CLEMSON TIGERS | W 93-78 | 4-5 | T. Guzman 20 | T. Clark 7 | M. Sweet 11 |
| December 16, 2042 | IOWA STATE CYCLONES | W 81-76 | 5-5 | T. Guzman 21 | T. Guzman 5 | D. Dunbar 11 |
| December 21, 2042 | @ Illinois Fighting Illini | L 77-94 | 5-6 | M. Sweet 17 | J. Ellis 3 | M. Sweet 10 |
| December 30, 2042 | KENTUCKY WILDCATS* | L 62-80 | 5-7 | M. Sweet 18 | T. Guzman 5 | M. Sweet 12 |
| January 3, 2043 | @ Auburn Tigers* | W 77-68 | 6-7 | M. Sweet 17 | A. Blakes 4 | A. Blakes 10 |
| January 6, 2043 | @ Tennessee Volunteers* | L 68-80 | 6-8 | P. Gregg 13 | T. Guzman 5 | P. Gregg 9 |
| January 10, 2043 | TEXAS LONGHORNS* | W 77-65 | 7-8 | J. Ellis 16 | T. Guzman 8 | M. Sweet 9 |
| January 13, 2043 | @ #13 LSU Tigers* | L 61-78 | 7-9 | D. Dunbar 13 | T. Guzman 2 | M. Sweet 9 |
| January 17, 2043 | ARKANSAS RAZORBACKS* | W 70-68 | 8-9 | M. Sweet 17 | J. Ellis 6 | M. Sweet 13 |
| January 20, 2043 | TEXAS A&M AGGIES* | L 76-82 | 8-10 | J. Ellis 18 | T. Guzman 5 | A. Blakes 13 |
| January 24, 2043 | @ Florida Gators* | L 66-84 | 8-11 | T. Guzman 14 | T. Guzman 5 | M. Sweet 9 |
| January 27, 2043 | GEORGIA BULLDOGS* | W 85-53 | 9-11 | J. Ellis 26 | T. Guzman 6 | A. Blakes 15 |
| February 3, 2043 | @ Missouri Tigers* | L 55-76 | 9-12 | K. Price 10 | T. Guzman 4 | M. Sweet 9 |
| February 7, 2043 | @ Mississippi State Bulldogs* | L 73-74 | 9-13 | T. Clark 21 | T. Guzman 5 | A. Blakes 9 |
| February 10, 2043 | VANDERBILT COMMODORES* | W 88-72 | 10-13 | A. Blakes 21 | T. Guzman 6 | A. Blakes 10 |
| February 14, 2043 | @ Ole Miss Rebels (16-9, 6-6, 9-5 Home)* | - | | | | |
| February 17, 2043 | LSU TIGERS (19-6, 9-3, 4-2 Away)* | - | | | | |
| February 21, 2043 | FLORIDA GATORS (13-10, 7-5, 3-6 Away)* | - | | | | |
| February 24, 2043 | @ Alabama Crimson Tide (18-8, 8-5, 11-2 Home)* | - | | | | |
| February 28, 2043 | OKLAHOMA SOONERS (11-13, 4-8, 1-8 Away)* | - | | | | |
| March 3, 2043 | @ Vanderbilt Commodores (17-6, 7-5, 13-0 Home)* | - | | | | |
