| November 16, 2042 | @ Indiana Hoosiers | L 67-86 | 0-1 | P. Harrington 13 | T. Conrad 6 | J. McTyer 7 |
| November 18, 2042 | @ Ole Miss Rebels | L 91-105 | 0-2 | J. Ridges 17 | J. Ridges 4 | E. Mallory 6 |
| November 23, 2042 | TROY TROJANS | L 60-81 | 0-3 | S. England 13 | P. Harrington 4 | S. England 8 |
| November 25, 2042 | RADFORD HIGHLANDERS | W 92-76 | 1-3 | P. Harrington 20 | W. Bartlett 8 | S. England 7 |
| November 28, 2042 | MD-EASTERN SHORE HAWKS | L 65-81 | 1-4 | T. Conrad 20 | W. Bartlett 7 | J. Ridges 8 |
| December 2, 2042 | CAL ST. FULLERTON TITANS | W 84-77 | 2-4 | P. Harrington 16 | T. Conrad 7 | M. Nettles 7 |
| December 6, 2042 | @ High Point Panthers | W 67-55 | 3-4 | P. Harrington 14 | J. Ridges 4 | M. Nettles 11 |
| December 9, 2042 | @ UC Santa Barbara Gauchos | W 76-75 OT | 4-4 | P. Harrington 20 | T. Conrad 5 | J. Ridges 8 |
| December 13, 2042 | BELLARMINE KNIGHTS | L 66-74 | 4-5 | J. Ridges 13 | J. Burdick 4 | N. Price 7 |
| December 19, 2042 | @ Idaho Vandals | L 75-93 | 4-6 | J. McTyer 19 | W. Bartlett 6 | E. Mallory 4 |
| December 27, 2042 | @ La Salle Explorers | L 73-81 | 4-7 | J. McTyer 14 | T. Conrad 4 | M. Nettles 7 |
| January 2, 2043 | SIU EDWARDSVILLE COUGARS* | W 79-77 OT | 5-7 | M. Nettles 20 | T. Conrad 8 | S. England 8 |
| January 4, 2043 | @ UT Martin Skyhawks* | L 77-79 | 5-8 | J. McTyer 18 | W. Bartlett 8 | T. Conrad 4 |
| January 9, 2043 | WESTERN ILLINOIS LEATHERNECKS* | W 81-76 | 6-8 | W. Bartlett 14 | W. Bartlett 7 | P. Harrington 7 |
| January 13, 2043 | @ Eastern Illinois Panthers* | L 78-95 | 6-9 | C. Wells 14 | P. Harrington 4 | J. McTyer 3 |
| January 18, 2043 | TENNESSEE TECH GOLDEN EAGLES* | W 81-73 | 7-9 | J. McTyer 17 | T. Conrad 6 | J. Ridges 6 |
| January 20, 2043 | UT MARTIN SKYHAWKS* | W 78-67 | 8-9 | P. Harrington 16 | W. Bartlett 4 | M. Nettles 8 |
| January 23, 2043 | MOREHEAD STATE EAGLES* | W 69-65 | 9-9 | W. Bartlett 16 | T. Conrad 4 | S. England 8 |
| January 25, 2043 | @ Lindenwood Lions* | W 82-78 | 10-9 | P. Harrington 19 | T. Conrad 5 | M. Nettles 8 |
| January 27, 2043 | @ Little Rock Trojans* | W 78-66 OT | 11-9 | P. Harrington 16 | W. Bartlett 5 | M. Nettles 10 |
| February 1, 2043 | TENNESSEE STATE TIGERS* | L 64-75 | 11-10 | P. Harrington 14 | T. Conrad 4 | S. England 6 |
| February 6, 2043 | @ SE Missouri State Redhawks* | W 66-57 | 12-10 | P. Harrington 16 | T. Conrad 5 | S. England 8 |
| February 8, 2043 | @ Morehead State Eagles* | L 66-75 | 12-11 | J. McTyer 13 | M. Nettles 5 | P. Harrington 7 |
| February 13, 2043 | @ Tennessee State Tigers* | L 62-103 | 12-12 | P. Harrington 12 | P. Harrington 4 | J. McTyer 5 |
| February 17, 2043 | @ Tennessee Tech Golden Eagles* | L 67-81 | 12-13 | P. Harrington 14 | T. Conrad 3 | S. England 8 |
| February 20, 2043 | @ Western Illinois Leathernecks* | W 84-71 | 13-13 | P. Harrington 19 | W. Bartlett 6 | J. McTyer 5 |
| February 22, 2043 | LITTLE ROCK TROJANS* | W 91-65 | 14-13 | P. Harrington 24 | T. Conrad 5 | M. Nettles 10 |
| February 27, 2043 | EASTERN ILLINOIS PANTHERS* | L 70-73 | 14-14 | P. Harrington 23 | P. Harrington 3 | P. Harrington 6 |
| March 1, 2043 | SE MISSOURI STATE REDHAWKS* | L 67-85 | 14-15 | J. McTyer 13 | W. Bartlett 6 | P. Harrington 5 |
| March 5, 2043 | LINDENWOOD LIONS OVC Tournament | W 72-63 | 15-15 | P. Harrington 26 | J. McTyer 3 | S. England 10 |
| March 6, 2043 | @ SIU Edwardsville Cougars OVC Tournament | L 64-79 | 15-16 | P. Harrington 13 | T. Conrad 5 | J. Ridges 7 |
