| November 16, 2042 | ILLINOIS STATE REDBIRDS | W 88-73 | 1-0 | D. Jones 20 | J. Pittman 6 | J. Rowe 11 |
| November 19, 2042 | SOUTH DAKOTA STATE JACKRABBITS | L 65-79 | 1-1 | J. Cable 16 | C. Floyd 6 | J. Pittman 8 |
| November 23, 2042 | SAINT FRANCIS (PA) RED FLASH | L 78-85 | 1-2 | C. Floyd 22 | C. Cooper 4 | J. Cable 7 |
| November 25, 2042 | @ #18 Utah State Aggies Myrtle Beach Invitational | W 90-87 | 2-2 | C. Floyd 22 | J. Cable 7 | J. Rowe 9 |
| November 26, 2042 | @ #20 LSU Tigers Myrtle Beach Invitational | L 73-80 | 2-3 | C. Floyd 21 | C. Cooper 3 | J. Rowe 16 |
| November 30, 2042 | CHICAGO STATE COUGARS | W 77-55 | 3-3 | D. Jones 17 | C. Floyd 3 | J. Rowe 8 |
| December 3, 2042 | FURMAN PALADINS | W 64-53 | 4-3 | C. Cooper 16 | C. Floyd 7 | J. Rowe 9 |
| December 7, 2042 | @ #15 Purdue Boilermakers | L 71-79 | 4-4 | C. Floyd 21 | C. Cooper 5 | C. Floyd 10 |
| December 13, 2042 | TCU HORNED FROGS | W 70-62 | 5-4 | D. Jones 12 | C. Cooper 3 | J. Rowe 13 |
| December 20, 2042 | NEW HAMPSHIRE WILDCATS | W 93-77 | 6-4 | J. Rowe 18 | C. Floyd 8 | J. Rowe 9 |
| December 26, 2042 | @ Pittsburgh Panthers* | L 58-69 | 6-5 | J. Tyler 14 | C. Cooper 5 | D. Jones 10 |
| December 28, 2042 | @ Clemson Tigers* | L 77-87 | 6-6 | D. Jones 17 | J. Cable 3 | J. Rowe 15 |
| January 2, 2043 | #22 FLORIDA STATE SEMINOLES* | W 86-77 | 7-6 | C. Floyd 13 | C. Cooper 7 | J. Rowe 10 |
| January 4, 2043 | @ NC State Wolfpack* | W 74-68 | 8-6 | D. Jones 14 | C. Cooper 6 | D. Jones 8 |
| January 9, 2043 | CALIFORNIA GOLDEN BEARS* | W 85-59 | 9-6 | S. Tracy 17 | C. Cooper 3 | S. Tracy 14 |
| January 11, 2043 | GEORGIA TECH YELLOW JACKETS* | L 74-76 | 9-7 | C. Floyd 16 | C. Cooper 4 | J. Rowe 10 |
| January 16, 2043 | WAKE FOREST DEMON DEACONS* | W 93-85 | 10-7 | D. Jones 20 | C. Cooper 5 | D. Jones 8 |
| January 18, 2043 | MIAMI (FL) HURRICANES* | W 83-71 | 11-7 | C. Floyd 15 | C. Cooper 7 | S. Tracy 7 |
| January 23, 2043 | @ Virginia Tech Hokies* | W 91-66 | 12-7 | C. Floyd 18 | C. Floyd 4 | J. Rowe 13 |
| January 25, 2043 | @ #13 Notre Dame Fighting Irish* | L 86-101 | 12-8 | D. Jones 22 | C. Cooper 4 | S. Tracy 11 |
| January 30, 2043 | DUKE BLUE DEVILS* | L 63-77 | 12-9 | D. Jones 13 | M. Ravellino 3 | S. Tracy 11 |
| February 1, 2043 | @ Syracuse Orange* | W 70-66 | 13-9 | J. Rowe 14 | M. Ravellino 7 | J. Rowe 9 |
| February 6, 2043 | @ #1 North Carolina Tar Heels* | L 69-87 | 13-10 | C. Floyd 20 | C. Cooper 7 | J. Cable 7 |
| February 8, 2043 | @ #9 Stanford Cardinal* | L 74-89 | 13-11 | C. Floyd 20 | J. Rowe 3 | C. Floyd 6 |
| February 13, 2043 | @ Boston College Eagles (7-16, 4-10, 5-7 Home)* | - | | | | |
| February 15, 2043 | VIRGINIA CAVALIERS (9-14, 7-7, 3-9 Away)* | - | | | | |
| February 20, 2043 | LOUISVILLE CARDINALS (15-10, 6-8, 4-5 Away)* | - | | | | |
| February 22, 2043 | NC STATE WOLFPACK (15-8, 9-5, 3-5 Away)* | - | | | | |
| February 27, 2043 | BOSTON COLLEGE EAGLES (7-16, 4-10, 2-8 Away)* | - | | | | |
| March 1, 2043 | @ Virginia Cavaliers (9-14, 7-7, 6-4 Home)* | - | | | | |
