| November 14, 2042 | VERMONT CATAMOUNTS NIT Season Tip-Off | W 85-54 | 1-0 | C. Wane 14 | A. Eaton 7 | B. Houck 11 |
| November 16, 2042 | @ #7 Butler Bulldogs NIT Season Tip-Off | W 82-80 | 2-0 | C. Burns 25 | C. Burns 3 | C. Burns 9 |
| November 18, 2042 | @ #2 Baylor Bears NIT Season Tip-Off | L 61-74 | 2-1 | C. Burns 11 | E. Childress 5 | C. Wane 9 |
| November 21, 2042 | GEORGE WASHINGTON COLONIALS | W 71-58 | 3-1 | C. Burns 22 | N. Woolfolk 8 | B. Houck 9 |
| November 25, 2042 | ALABAMA CRIMSON TIDE | W 81-67 | 4-1 | C. Burns 17 | N. Woolfolk 5 | C. Wane 12 |
| November 28, 2042 | NEW MEXICO LOBOS | W 70-65 | 5-1 | C. Burns 15 | N. Woolfolk 5 | C. Wane 12 |
| December 3, 2042 | CHARLOTTE 49ERS | W 90-56 | 6-1 | K. Marsh 23 | N. Woolfolk 6 | C. Wane 11 |
| December 7, 2042 | @ #6 Notre Dame Fighting Irish | L 68-101 | 6-2 | C. Wane 17 | A. Eaton 4 | B. Houck 6 |
| December 8, 2042 | FURMAN PALADINS | L 56-61 | 6-3 | C. Burns 19 | N. Woolfolk 4 | B. Houck 10 |
| December 13, 2042 | CALIFORNIA GOLDEN BEARS | W 87-68 | 7-3 | C. Wane 27 | N. Woolfolk 4 | C. Wane 11 |
| December 19, 2042 | NEBRASKA CORNHUSKERS | W 61-43 | 8-3 | C. Wane 16 | N. Woolfolk 3 | C. Wane 17 |
| December 23, 2042 | @ Missouri Tigers | L 69-87 | 8-4 | C. Burns 17 | B. Houck 4 | C. Wane 10 |
| December 26, 2042 | ABILENE CHRISTIAN WILDCATS | W 81-62 | 9-4 | C. Burns 24 | E. Childress 5 | B. Houck 9 |
| January 2, 2043 | PORTLAND PILOTS* | W 87-61 | 10-4 | C. Burns 22 | N. Woolfolk 9 | C. Wane 10 |
| January 4, 2043 | @ Santa Clara Broncos* | W 84-67 | 11-4 | C. Burns 20 | N. Woolfolk 4 | C. Wane 12 |
| January 9, 2043 | SAN DIEGO TOREROS* | L 59-61 | 11-5 | N. Woolfolk 14 | N. Woolfolk 3 | C. Burns 7 |
| January 13, 2043 | @ San Francisco Dons* | W 91-72 | 12-5 | C. Burns 22 | K. Marsh 7 | C. Wane 7 |
| January 18, 2043 | PEPPERDINE WAVES* | W 76-52 | 13-5 | C. Wane 17 | N. Woolfolk 8 | B. Houck 9 |
| January 20, 2043 | SANTA CLARA BRONCOS* | W 81-54 | 14-5 | C. Burns 26 | E. Childress 5 | C. Wane 10 |
| January 23, 2043 | OREGON STATE BEAVERS* | W 75-56 | 15-5 | C. Burns 21 | N. Woolfolk 8 | C. Wane 8 |
| January 25, 2043 | @ Washington State Cougars* | W 63-48 | 16-5 | K. Marsh 12 | N. Woolfolk 6 | C. Wane 14 |
| January 27, 2043 | @ Pacific Tigers* | W 90-77 | 17-5 | C. Wane 15 | N. Woolfolk 5 | C. Wane 9 |
| February 1, 2043 | #9 GONZAGA BULLDOGS* | W 76-69 | 18-5 | B. Houck 16 | N. Woolfolk 7 | K. Marsh 11 |
| February 6, 2043 | @ Loyola Marymount Lions* | W 91-68 | 19-5 | C. Burns 20 | N. Woolfolk 10 | B. Houck 7 |
| February 8, 2043 | @ Oregon State Beavers* | L 55-57 | 19-6 | K. Marsh 11 | N. Woolfolk 5 | B. Houck 12 |
| February 13, 2043 | @ Gonzaga Bulldogs (22-4, 10-3, 11-2 Home)* | - | | | | |
| February 17, 2043 | @ Pepperdine Waves (8-16, 3-10, 5-4 Home)* | - | | | | |
| February 20, 2043 | @ San Diego Toreros (5-19, 3-10, 3-8 Home)* | - | | | | |
| February 22, 2043 | PACIFIC TIGERS (10-14, 5-8, 3-6 Away)* | - | | | | |
| February 27, 2043 | SAN FRANCISCO DONS (10-14, 6-7, 3-6 Away)* | - | | | | |
| March 1, 2043 | LOYOLA MARYMOUNT LIONS (6-17, 2-10, 2-9 Away)* | - | | | | |
