| November 16, 2042 | @ Penn State Nittany Lions | L 69-99 | 0-1 | G. Guyton 16 | K. Cook 5 | A. Baer 5 |
| November 18, 2042 | @ Maine Black Bears | W 94-87 | 1-1 | G. Guyton 34 | K. Cook 6 | B. Chambers 7 |
| November 26, 2042 | @ North Dakota St. Bison | L 69-77 | 1-2 | G. Guyton 14 | M. May 4 | A. Baer 11 |
| November 29, 2042 | @ Nicholls State Colonels | L 61-78 | 1-3 | G. Guyton 24 | K. Cook 4 | J. Ellington 10 |
| December 2, 2042 | @ Oklahoma Sooners | L 61-86 | 1-4 | G. Guyton 13 | K. Cook 6 | A. Baer 8 |
| December 6, 2042 | @ Charleston Southern Buccaneers | L 80-104 | 1-5 | G. Guyton 21 | K. Cook 7 | A. Baer 6 |
| December 10, 2042 | CORNELL BIG RED | W 80-79 | 2-5 | G. Guyton 26 | K. Cook 6 | A. Baer 9 |
| December 13, 2042 | @ Arkansas State Red Wolves | L 76-89 | 2-6 | G. Guyton 22 | K. Cook 4 | B. Chambers 6 |
| December 15, 2042 | WAGNER SEAHAWKS | L 53-74 | 2-7 | G. Guyton 12 | K. Cook 3 | B. Chambers 7 |
| December 26, 2042 | @ Washington State Cougars | L 64-73 | 2-8 | M. May 15 | K. Cook 5 | M. May 11 |
| December 29, 2042 | COPPIN STATE EAGLES | W 79-73 | 3-8 | G. Guyton 27 | K. Cook 5 | K. Cook 8 |
| January 2, 2043 | EASTERN ILLINOIS PANTHERS* | L 73-82 | 3-9 | G. Guyton 22 | M. May 4 | B. Chambers 8 |
| January 4, 2043 | SOUTHERN INDIANA SCREAMING EAGLES* | W 79-77 | 4-9 | G. Guyton 21 | J. Ellington 5 | G. Guyton 9 |
| January 9, 2043 | @ Little Rock Trojans* | L 85-92 | 4-10 | G. Guyton 23 | K. Cook 7 | A. Baer 9 |
| January 11, 2043 | SIU EDWARDSVILLE COUGARS* | W 86-84 | 5-10 | B. Chambers 18 | K. Cook 4 | J. Ellington 7 |
| January 16, 2043 | @ Lindenwood Lions* | L 67-74 | 5-11 | G. Guyton 17 | K. Cook 3 | J. Ellington 6 |
| January 20, 2043 | @ Southern Indiana Screaming Eagles* | L 67-78 | 5-12 | M. May 15 | N. Keady 4 | A. Baer 7 |
| January 25, 2043 | MOREHEAD STATE EAGLES* | W 94-77 | 6-12 | A. Baer 20 | K. Cook 5 | A. Baer 8 |
| January 27, 2043 | @ Tennessee State Tigers* | L 81-97 | 6-13 | G. Guyton 31 | K. Cook 6 | G. Guyton 7 |
| January 30, 2043 | @ SE Missouri State Redhawks* | L 78-82 | 6-14 | G. Guyton 14 | K. Cook 9 | A. Baer 7 |
| February 1, 2043 | TENNESSEE TECH GOLDEN EAGLES* | W 63-60 | 7-14 | M. May 11 | K. Cook 5 | A. Baer 6 |
| February 6, 2043 | TENNESSEE STATE TIGERS* | L 73-93 | 7-15 | G. Guyton 24 | K. Cook 4 | G. Guyton 5 |
| February 8, 2043 | @ Western Illinois Leathernecks* | L 77-90 | 7-16 | G. Guyton 18 | K. Cook 6 | J. Ellington 7 |
| February 13, 2043 | LINDENWOOD LIONS (9-14, 5-7, 2-10 Away)* | - | | | | |
| February 15, 2043 | SE MISSOURI STATE REDHAWKS (14-9, 8-4, 6-5 Away)* | - | | | | |
| February 17, 2043 | @ SIU Edwardsville Cougars (14-9, 7-5, 9-0 Home)* | - | | | | |
| February 20, 2043 | @ Morehead State Eagles (11-13, 7-6, 5-4 Home)* | - | | | | |
| February 22, 2043 | @ Tennessee Tech Golden Eagles (8-16, 3-10, 7-6 Home)* | - | | | | |
| March 1, 2043 | LITTLE ROCK TROJANS (5-19, 2-11, 2-10 Away)* | - | | | | |
