| November 16, 2042 | @ Duke Blue Devils | L 69-78 | 0-1 | V. Drake 13 | W. Kahn 4 | V. Drake 8 |
| November 17, 2042 | MORGAN STATE BEARS | L 68-70 | 0-2 | V. Drake 14 | C. Keys 4 | A. Melikis 10 |
| November 23, 2042 | MONMOUTH HAWKS | W 76-62 | 1-2 | V. Drake 14 | C. Keys 4 | A. Melikis 13 |
| November 25, 2042 | CALIFORNIA BAPTIST LANCERS | W 86-61 | 2-2 | L. Taylor 20 | C. Keys 8 | A. Melikis 8 |
| November 30, 2042 | BOISE STATE BRONCOS | W 87-65 | 3-2 | W. Kahn 19 | A. Melikis 4 | A. Melikis 11 |
| December 1, 2042 | EASTERN WASHINGTON EAGLES | W 97-84 | 4-2 | B. Callahan 16 | V. Drake 7 | L. Ricci 6 |
| December 6, 2042 | MIAMI (OH) RED HAWKS | W 74-69 | 5-2 | B. Callahan 16 | C. Keys 6 | T. Donaldson 8 |
| December 9, 2042 | LOYOLA MARYMOUNT LIONS Baha Mar Hoops Bahamas Championship | W 81-60 | 6-2 | L. Taylor 20 | C. Keys 4 | E. Gasco 5 |
| December 10, 2042 | ARIZONA STATE SUN DEVILS Baha Mar Hoops Bahamas Championship | W 73-68 | 7-2 | V. Drake 17 | C. Keys 7 | A. Melikis 9 |
| December 11, 2042 | @ Georgia Southern Eagles Baha Mar Hoops Bahamas Championship | L 65-75 | 7-3 | V. Drake 13 | W. Kahn 4 | T. Donaldson 10 |
| December 13, 2042 | TEXAS TECH RED RAIDERS | W 59-57 | 8-3 | C. Keys 14 | V. Drake 4 | A. Melikis 8 |
| December 16, 2042 | DAVIDSON WILDCATS | L 70-82 | 8-4 | L. Taylor 14 | C. Keys 5 | A. Melikis 10 |
| December 21, 2042 | #23 XAVIER MUSKETEERS | L 86-90 | 8-5 | E. Gasco 20 | W. Kahn 6 | B. Callahan 8 |
| December 30, 2042 | ARKANSAS RAZORBACKS* | W 94-74 | 9-5 | C. Keys 16 | C. Keys 8 | E. Gasco 9 |
| January 3, 2043 | @ Ole Miss Rebels* | L 73-94 | 9-6 | L. Ricci 15 | C. Keys 7 | A. Melikis 13 |
| January 6, 2043 | @ Texas Longhorns* | L 54-77 | 9-7 | T. Donaldson 12 | A. Melikis 3 | E. Gasco 7 |
| January 10, 2043 | MISSOURI TIGERS* | W 90-77 | 10-7 | L. Ricci 17 | C. Keys 5 | T. Donaldson 9 |
| January 13, 2043 | @ Tennessee Volunteers* | L 67-75 | 10-8 | C. Keys 11 | V. Drake 4 | A. Melikis 11 |
| January 20, 2043 | @ South Carolina Gamecocks* | W 82-76 | 11-8 | W. Kahn 14 | C. Keys 5 | B. Callahan 8 |
| January 24, 2043 | VANDERBILT COMMODORES* | W 80-70 | 12-8 | V. Drake 17 | W. Kahn 4 | A. Melikis 12 |
| January 27, 2043 | #25 MISSISSIPPI STATE BULLDOGS* | L 58-74 | 12-9 | C. Keys 12 | A. Melikis 5 | A. Melikis 7 |
| January 31, 2043 | @ Georgia Bulldogs* | W 96-68 | 13-9 | L. Ricci 23 | C. Keys 9 | V. Drake 9 |
| February 3, 2043 | TEXAS LONGHORNS* | L 65-67 | 13-10 | T. Donaldson 12 | C. Keys 3 | B. Callahan 9 |
| February 7, 2043 | @ Missouri Tigers* | L 73-76 | 13-11 | C. Keys 18 | C. Keys 5 | L. Ricci 11 |
| February 10, 2043 | @ Kentucky Wildcats* | W 72-62 | 14-11 | A. Melikis 19 | C. Keys 7 | L. Ricci 6 |
| February 14, 2043 | AUBURN TIGERS* | W 75-67 | 15-11 | C. Keys 13 | C. Keys 5 | V. Drake 8 |
| February 17, 2043 | OKLAHOMA SOONERS* | L 66-78 | 15-12 | W. Kahn 16 | W. Kahn 3 | A. Melikis 7 |
| February 21, 2043 | #21 ALABAMA CRIMSON TIDE* | L 63-74 | 15-13 | L. Ricci 10 | C. Keys 7 | C. Keys 6 |
| February 24, 2043 | @ Florida Gators* | W 81-69 | 16-13 | L. Taylor 18 | V. Drake 5 | B. Callahan 11 |
| February 28, 2043 | @ #17 LSU Tigers* | L 81-93 | 16-14 | V. Drake 21 | C. Keys 7 | B. Callahan 8 |
| March 3, 2043 | #20 TENNESSEE VOLUNTEERS* | L 57-70 | 16-15 | L. Ricci 15 | C. Keys 7 | A. Melikis 9 |
| March 8, 2043 | OKLAHOMA SOONERS SEC Tournament | W 83-58 | 17-15 | B. Callahan 17 | C. Keys 7 | B. Callahan 11 |
| March 9, 2043 | @ Kentucky Wildcats SEC Tournament | W 81-76 | 18-15 | L. Taylor 21 | C. Keys 6 | A. Melikis 9 |
| March 10, 2043 | @ Ole Miss Rebels SEC Tournament | W 78-75 | 19-15 | B. Callahan 16 | C. Keys 6 | C. Keys 8 |
| March 11, 2043 | @ #21 Tennessee Volunteers SEC Tournament | L 62-70 | 19-16 | B. Callahan 13 | C. Keys 4 | A. Melikis 7 |
