| November 13, 2042 | PENNSYLVANIA QUAKERS | W 82-63 | 1-0 | M. Sullivan 18 | B. Irvin 8 | M. Sullivan 8 |
| November 16, 2042 | SAMFORD BULLDOGS | W 80-60 | 2-0 | B. Irvin 16 | B. Irvin 7 | M. Sullivan 10 |
| November 19, 2042 | GRAMBLING TIGERS | W 99-93 OT | 3-0 | B. Irvin 25 | T. Salgado 5 | T. Salgado 7 |
| November 21, 2042 | UCF KNIGHTS WSSN Classic | W 86-75 | 4-0 | J. Rowe 21 | B. Irvin 4 | T. Salgado 7 |
| November 22, 2042 | @ Miami (FL) Hurricanes WSSN Classic | L 66-94 | 4-1 | S. Lofton 13 | B. Irvin 7 | M. Sullivan 7 |
| November 26, 2042 | #7 NORTH CAROLINA TAR HEELS | L 71-86 | 4-2 | T. Salgado 20 | B. Irvin 8 | J. Rowe 5 |
| November 30, 2042 | ARKANSAS PINE BLUFF GOLDEN LIONS | L 68-74 | 4-3 | T. Salgado 23 | B. Irvin 4 | T. Salgado 6 |
| December 3, 2042 | COASTAL CAROLINA CHANTICLEERS | W 92-77 | 5-3 | T. Salgado 18 | B. Irvin 4 | S. Lofton 7 |
| December 5, 2042 | NORTHERN COLORADO BEARS | L 58-69 | 5-4 | T. Salgado 11 | T. Henson 3 | S. Lofton 10 |
| December 13, 2042 | @ Loyola Marymount Lions | L 68-84 | 5-5 | T. Salgado 28 | B. Irvin 4 | S. Lofton 6 |
| December 26, 2042 | WASHINGTON HUSKIES (3-6, 0-0, 0-3 Away)* | - | | | | |
| December 28, 2042 | IOWA HAWKEYES (9-1, 0-0, 3-1 Away)* | - | | | | |
| January 2, 2043 | @ Wisconsin Badgers (5-4, 0-0, 5-2 Home)* | - | | | | |
| January 4, 2043 | @ Maryland Terrapins (7-3, 0-0, 5-0 Home)* | - | | | | |
| January 9, 2043 | OHIO STATE BUCKEYES (4-5, 0-0, 0-1 Away)* | - | | | | |
| January 11, 2043 | USC TROJANS (8-2, 0-0, 0-2 Away)* | - | | | | |
| January 16, 2043 | @ Minnesota Golden Gophers (9-2, 0-0, 5-1 Home)* | - | | | | |
| January 18, 2043 | INDIANA HOOSIERS (7-4, 0-0, 1-3 Away)* | - | | | | |
| January 23, 2043 | @ Nebraska Cornhuskers (3-6, 0-0, 3-3 Home)* | - | | | | |
| January 25, 2043 | @ Michigan Wolverines (4-5, 0-0, 4-2 Home)* | - | | | | |
| January 30, 2043 | @ Oregon Ducks (4-5, 0-0, 4-2 Home)* | - | | | | |
| February 1, 2043 | @ Michigan State Spartans (7-3, 0-0, 4-0 Home)* | - | | | | |
| February 6, 2043 | PURDUE BOILERMAKERS (10-1, 0-0, 0-0 Away)* | - | | | | |
| February 8, 2043 | PENN STATE NITTANY LIONS (6-3, 0-0, 1-2 Away)* | - | | | | |
| February 13, 2043 | @ Northwestern Wildcats (5-6, 0-0, 2-3 Home)* | - | | | | |
| February 15, 2043 | @ Illinois Fighting Illini (7-2, 0-0, 5-0 Home)* | - | | | | |
| February 20, 2043 | RUTGERS SCARLET KNIGHTS (8-1, 0-0, 0-0 Away)* | - | | | | |
| February 22, 2043 | MARYLAND TERRAPINS (7-3, 0-0, 1-2 Away)* | - | | | | |
| February 27, 2043 | @ Washington Huskies (3-6, 0-0, 3-2 Home)* | - | | | | |
| March 1, 2043 | WISCONSIN BADGERS (5-4, 0-0, 0-1 Away)* | - | | | | |
