| November 13, 2042 | YALE BULLDOGS | L 71-93 | 0-1 | A. Driver 23 | K. Blevins 3 | K. Allison 9 |
| November 14, 2042 | MORGAN STATE BEARS | L 67-72 | 0-2 | A. Driver 17 | K. Blevins 6 | T. Mitchell 8 |
| November 19, 2042 | WILLIAM & MARY TRIBE | W 72-70 | 1-2 | D. Levine 24 | K. Blevins 6 | T. Michaels 9 |
| November 22, 2042 | MAINE BLACK BEARS | W 72-63 | 2-2 | A. Driver 19 | K. Blevins 5 | A. Driver 9 |
| November 25, 2042 | SOUTH CAROLINA UPSTATE SPARTANS | W 81-77 | 3-2 | T. Mitchell 18 | K. Blevins 6 | R. Wilkins 8 |
| November 28, 2042 | IDAHO VANDALS | W 75-54 | 4-2 | T. Michaels 25 | K. Blevins 9 | T. Michaels 11 |
| December 9, 2042 | RICE OWLS Cayman Islands Classic | W 77-76 | 5-2 | T. Mitchell 18 | K. Blevins 8 | T. Michaels 10 |
| December 10, 2042 | @ Oklahoma Sooners Cayman Islands Classic | W 73-57 | 6-2 | R. Wilkins 13 | K. Blevins 7 | T. Michaels 10 |
| December 11, 2042 | @ Indiana Hoosiers Cayman Islands Classic | L 69-88 | 6-3 | D. Levine 16 | T. Mitchell 3 | L. D'Angelo 6 |
| December 13, 2042 | UTAH STATE AGGIES | L 74-88 | 6-4 | K. Allison 13 | K. Blevins 6 | T. Michaels 12 |
| December 21, 2042 | IOWA HAWKEYES | W 82-80 | 7-4 | K. Allison 17 | K. Blevins 5 | T. Michaels 8 |
| December 28, 2042 | @ Colorado Buffaloes* | L 65-84 | 7-5 | D. Levine 14 | K. Blevins 6 | T. Michaels 8 |
| December 30, 2042 | BYU COUGARS* | W 82-77 | 8-5 | D. Levine 17 | K. Blevins 7 | K. Allison 9 |
| January 4, 2043 | @ Texas Tech Red Raiders* | W 76-72 | 9-5 | T. Michaels 16 | K. Blevins 5 | T. Michaels 10 |
| January 6, 2043 | ARIZONA WILDCATS* | W 90-76 | 10-5 | A. Driver 14 | T. Mitchell 6 | T. Michaels 13 |
| January 11, 2043 | @ Arizona State Sun Devils* | W 70-67 | 11-5 | K. Allison 24 | K. Blevins 3 | T. Michaels 8 |
| January 13, 2043 | #3 KANSAS JAYHAWKS* | L 52-70 | 11-6 | K. Allison 11 | K. Allison 5 | T. Michaels 8 |
| January 18, 2043 | @ #1 Baylor Bears* | L 59-83 | 11-7 | D. Levine 16 | K. Blevins 4 | T. Michaels 15 |
| January 20, 2043 | COLORADO BUFFALOES* | W 77-67 | 12-7 | D. Levine 20 | T. Mitchell 3 | T. Michaels 8 |
| January 25, 2043 | #15 OKLAHOMA STATE COWBOYS* | W 82-79 | 13-7 | L. D'Angelo 21 | T. Mitchell 8 | R. Wilkins 8 |
| January 27, 2043 | @ Arizona Wildcats* | L 80-84 | 13-8 | D. Levine 18 | T. Mitchell 6 | T. Michaels 5 |
| February 1, 2043 | KANSAS STATE WILDCATS* | L 54-80 | 13-9 | K. Allison 19 | K. Blevins 3 | T. Mitchell 7 |
| February 3, 2043 | @ TCU Horned Frogs* | W 76-73 | 14-9 | K. Allison 18 | K. Blevins 6 | T. Mitchell 8 |
| February 8, 2043 | @ #22 Oklahoma State Cowboys* | W 77-70 | 15-9 | A. Driver 21 | K. Blevins 5 | T. Michaels 11 |
| February 10, 2043 | UCF KNIGHTS* | W 84-69 | 16-9 | A. Driver 18 | K. Blevins 6 | K. Allison 7 |
| February 13, 2043 | HOUSTON COUGARS (16-7, 9-5, 4-5 Away)* | - | | | | |
| February 20, 2043 | @ West Virginia Mountaineers (19-6, 10-4, 11-3 Home)* | - | | | | |
| February 22, 2043 | @ Cincinnati Bearcats (13-12, 4-10, 8-7 Home)* | - | | | | |
| February 24, 2043 | IOWA STATE CYCLONES (3-20, 1-13, 0-9 Away)* | - | | | | |
| March 1, 2043 | TCU HORNED FROGS (15-9, 8-6, 3-6 Away)* | - | | | | |
| March 3, 2043 | @ Kansas Jayhawks (20-5, 10-4, 12-1 Home)* | - | | | | |
