| November 16, 2042 | WESTERN KENTUCKY HILLTOPPERS | L 70-73 | 0-1 | R. Partridge 19 | C. Austin 8 | R. Partridge 8 |
| November 19, 2042 | NORTH DAKOTA FIGHTING HAWKS | W 83-77 OT | 1-1 | R. Partridge 25 | C. Austin 6 | R. Partridge 7 |
| November 22, 2042 | ALABAMA CRIMSON TIDE | L 64-66 OT | 1-2 | B. Ross 23 | C. Austin 5 | D. Augustine 10 |
| November 25, 2042 | NORTHERN KENTUCKY NORSE ESPN Events Invitational | W 87-81 | 2-2 | W. Matson 23 | C. Austin 11 | W. Matson 12 |
| November 26, 2042 | BUCKNELL BISON ESPN Events Invitational | L 72-75 | 2-3 | B. Ross 18 | C. Austin 3 | W. Matson 10 |
| November 30, 2042 | AUSTIN PEAY GOVERNORS | W 71-50 | 3-3 | B. Ross 24 | C. Austin 7 | W. Matson 12 |
| December 7, 2042 | @ #3 Minnesota Golden Gophers | L 64-73 | 3-4 | B. Ross 19 | B. Ross 4 | D. Augustine 10 |
| December 10, 2042 | WESTERN CAROLINA CATAMOUNTS | W 75-71 | 4-4 | B. Ross 23 | C. Austin 8 | B. Ross 8 |
| December 13, 2042 | @ Ohio State Buckeyes | L 73-84 | 4-5 | W. Matson 18 | B. Ross 4 | D. Augustine 7 |
| December 20, 2042 | VANDERBILT COMMODORES | L 81-92 | 4-6 | D. Augustine 22 | C. Austin 6 | D. Augustine 7 |
| December 26, 2042 | @ Georgia Tech Yellow Jackets (8-3, 0-0, 3-1 Home)* | - | | | | |
| December 28, 2042 | @ NC State Wolfpack (6-3, 0-0, 6-0 Home)* | - | | | | |
| January 2, 2043 | @ Virginia Cavaliers (2-7, 0-0, 1-2 Home)* | - | | | | |
| January 4, 2043 | STANFORD CARDINAL (11-1, 0-0, 1-1 Away)* | - | | | | |
| January 9, 2043 | CLEMSON TIGERS (2-7, 0-0, 1-3 Away)* | - | | | | |
| January 11, 2043 | @ California Golden Bears (1-8, 0-0, 1-4 Home)* | - | | | | |
| January 16, 2043 | @ Miami (FL) Hurricanes (9-2, 0-0, 5-0 Home)* | - | | | | |
| January 18, 2043 | NOTRE DAME FIGHTING IRISH (8-4, 0-0, 0-3 Away)* | - | | | | |
| January 23, 2043 | SMU MUSTANGS (6-4, 0-0, 0-1 Away)* | - | | | | |
| January 25, 2043 | @ Duke Blue Devils (5-4, 0-0, 4-1 Home)* | - | | | | |
| January 30, 2043 | @ Florida State Seminoles (7-2, 0-0, 7-0 Home)* | - | | | | |
| February 1, 2043 | NORTH CAROLINA TAR HEELS (10-1, 0-0, 2-1 Away)* | - | | | | |
| February 6, 2043 | @ Boston College Eagles (3-6, 0-0, 2-3 Home)* | - | | | | |
| February 8, 2043 | SYRACUSE ORANGE (6-3, 0-0, 1-1 Away)* | - | | | | |
| February 13, 2043 | WAKE FOREST DEMON DEACONS (3-7, 0-0, 2-3 Away)* | - | | | | |
| February 15, 2043 | LOUISVILLE CARDINALS (9-2, 0-0, 3-0 Away)* | - | | | | |
| February 20, 2043 | @ Pittsburgh Panthers (7-4, 0-0, 4-1 Home)* | - | | | | |
| February 22, 2043 | @ Stanford Cardinal (11-1, 0-0, 6-0 Home)* | - | | | | |
| February 27, 2043 | CALIFORNIA GOLDEN BEARS (1-8, 0-0, 0-3 Away)* | - | | | | |
| March 1, 2043 | PITTSBURGH PANTHERS (7-4, 0-0, 0-3 Away)* | - | | | | |
