| November 15, 2038 | @ #15 Minnesota Golden Gophers | L 68-93 | 0-1 | S. Webb 12 | K. Sherrell 6 | S. Webb 6 |
| November 18, 2038 | MANHATTAN JASPERS | W 72-59 | 1-1 | K. Sherrell 14 | A. Nobile 4 | N. Watkins 8 |
| November 21, 2038 | LOYOLA CHICAGO RAMBLERS Charleston Classic | W 70-67 | 2-1 | A. Nobile 18 | K. Sherrell 5 | N. Watkins 7 |
| November 22, 2038 | @ #23 Florida Gators Charleston Classic | L 70-89 | 2-2 | S. Webb 16 | K. Sherrell 6 | N. Watkins 7 |
| November 25, 2038 | @ Santa Clara Broncos | L 77-84 | 2-3 | K. Sherrell 17 | A. Nobile 4 | N. Chouest 10 |
| November 29, 2038 | CANISIUS GOLDEN GRIFFINS | W 82-66 | 3-3 | A. Nobile 15 | K. Sherrell 3 | K. Vichter 9 |
| December 2, 2038 | UC SANTA BARBARA GAUCHOS | W 87-58 | 4-3 | S. Webb 18 | K. Sherrell 9 | K. Sherrell 7 |
| December 6, 2038 | MARSHALL THUNDERING HERD | W 85-76 | 5-3 | D. Barrett 14 | K. Sherrell 7 | K. Sherrell 5 |
| December 13, 2038 | @ #3 Maryland Terrapins | W 74-62 | 6-3 | N. Chouest 16 | K. Sherrell 4 | N. Chouest 10 |
| December 19, 2038 | CAL POLY MUSTANGS | W 76-73 | 7-3 | A. Nobile 19 | K. Sherrell 5 | S. Webb 6 |
| December 26, 2038 | #12 FLORIDA STATE SEMINOLES* | W 86-85 | 8-3 | K. Sherrell 17 | K. Sherrell 5 | N. Chouest 8 |
| December 30, 2038 | VIRGINIA CAVALIERS* | W 82-73 | 9-3 | S. Webb 23 | A. Nobile 7 | N. Chouest 7 |
| January 2, 2039 | DUKE BLUE DEVILS* | W 62-48 | 10-3 | K. Sherrell 11 | D. Barrett 4 | N. Watkins 9 |
| January 6, 2039 | @ #17 Louisville Cardinals* | L 58-69 | 10-4 | S. Webb 11 | K. Sherrell 4 | A. Nobile 6 |
| January 11, 2039 | @ #13 Florida State Seminoles* | L 67-97 | 10-5 | N. Watkins 16 | D. Barrett 6 | N. Chouest 10 |
| January 13, 2039 | @ #24 NC State Wolfpack* | L 56-78 | 10-6 | D. Barrett 10 | K. Sherrell 4 | K. Vichter 8 |
| January 18, 2039 | CLEMSON TIGERS (10-6, 1-5, 2-2 Away)* | - | | | | |
| January 20, 2039 | GEORGIA TECH YELLOW JACKETS (11-5, 3-4, 1-3 Away)* | - | | | | |
| January 25, 2039 | @ Boston College Eagles (6-9, 3-2, 4-2 Home)* | - | | | | |
| January 27, 2039 | @ Miami (FL) Hurricanes (11-5, 5-1, 6-1 Home)* | - | | | | |
| February 1, 2039 | NOTRE DAME FIGHTING IRISH (15-1, 4-1, 3-0 Away)* | - | | | | |
| February 3, 2039 | SYRACUSE ORANGE (10-5, 3-3, 2-3 Away)* | - | | | | |
| February 8, 2039 | @ Clemson Tigers (10-6, 1-5, 8-4 Home)* | - | | | | |
| February 10, 2039 | @ Georgia Tech Yellow Jackets (11-5, 3-4, 10-2 Home)* | - | | | | |
| February 13, 2039 | @ Duke Blue Devils (7-8, 2-4, 7-3 Home)* | - | | | | |
| February 15, 2039 | PITTSBURGH PANTHERS (10-6, 5-1, 2-4 Away)* | - | | | | |
| February 17, 2039 | NORTH CAROLINA TAR HEELS (14-0, 5-0, 5-0 Away)* | - | | | | |
| February 20, 2039 | @ Virginia Cavaliers (9-9, 3-4, 9-2 Home)* | - | | | | |
| February 27, 2039 | WAKE FOREST DEMON DEACONS (4-11, 0-6, 1-6 Away)* | - | | | | |
| March 3, 2039 | @ Syracuse Orange (10-5, 3-3, 8-2 Home)* | - | | | | |
