| November 14, 2042 | @ #20 Saint Mary's Gaels NIT Season Tip-Off | L 54-85 | 0-1 | B. Barney 11 | B. Barney 2 | H. Andrews 11 |
| November 23, 2042 | @ Princeton Tigers | L 55-71 | 0-2 | J. Larkin 12 | G. O'Toole 3 | T. Braun 12 |
| November 24, 2042 | @ Oklahoma State Cowboys | L 55-100 | 0-3 | D. Eason 11 | T. Burton 6 | H. Andrews 7 |
| November 29, 2042 | @ Central Michigan Chippewas | L 73-85 | 0-4 | A. Kellogg 15 | J. Larkin 6 | T. Braun 8 |
| December 2, 2042 | SIENA SAINTS | L 68-71 | 0-5 | H. Andrews 11 | J. Larkin 8 | F. Crain 9 |
| December 6, 2042 | EASTERN KENTUCKY COLONELS | L 70-75 | 0-6 | G. O'Toole 15 | J. Larkin 7 | F. Crain 7 |
| December 9, 2042 | PURDUE FORT WAYNE MASTODONS | W 98-93 | 1-6 | G. O'Toole 31 | B. Barney 5 | G. O'Toole 7 |
| December 13, 2042 | @ Marist Red Foxes | L 63-78 | 1-7 | H. Andrews 11 | J. Larkin 5 | H. Andrews 10 |
| December 16, 2042 | @ Texas Tech Red Raiders | L 65-81 | 1-8 | G. O'Toole 12 | J. Larkin 3 | F. Crain 9 |
| December 20, 2042 | WRIGHT STATE RAIDERS | W 95-67 | 2-8 | A. Kellogg 22 | J. Larkin 7 | H. Andrews 6 |
| December 23, 2042 | HARVARD CRIMSON | W 87-66 | 3-8 | F. Crain 20 | J. Larkin 6 | F. Crain 11 |
| December 27, 2042 | @ Marshall Thundering Herd (3-7, 1-2 Home) | - | | | | |
| December 30, 2042 | @ Mercyhurst Lakers (8-4, 8-2 Home) | - | | | | |
| January 3, 2043 | @ Binghamton Bearcats (8-5, 0-0, 4-0 Home)* | - | | | | |
| January 6, 2043 | NJIT HIGHLANDERS (6-6, 0-0, 5-5 Away)* | - | | | | |
| January 10, 2043 | @ Bryant Bulldogs (5-7, 0-0, 4-1 Home)* | - | | | | |
| January 13, 2043 | NEW HAMPSHIRE WILDCATS (5-7, 0-0, 4-7 Away)* | - | | | | |
| January 17, 2043 | @ Albany Great Danes (6-6, 0-0, 2-0 Home)* | - | | | | |
| January 20, 2043 | UMBC RETRIEVERS (3-9, 0-0, 1-6 Away)* | - | | | | |
| January 24, 2043 | @ UMass Lowell River Hawks (2-10, 0-0, 2-0 Home)* | - | | | | |
| January 27, 2043 | MAINE BLACK BEARS (4-8, 0-0, 2-7 Away)* | - | | | | |
| February 3, 2043 | BINGHAMTON BEARCATS (8-5, 0-0, 4-5 Away)* | - | | | | |
| February 7, 2043 | @ NJIT Highlanders (6-6, 0-0, 1-1 Home)* | - | | | | |
| February 10, 2043 | BRYANT BULLDOGS (5-7, 0-0, 1-6 Away)* | - | | | | |
| February 14, 2043 | @ New Hampshire Wildcats (5-7, 0-0, 1-0 Home)* | - | | | | |
| February 17, 2043 | ALBANY GREAT DANES (6-6, 0-0, 4-6 Away)* | - | | | | |
| February 21, 2043 | @ UMBC Retrievers (3-9, 0-0, 2-3 Home)* | - | | | | |
| February 24, 2043 | UMASS LOWELL RIVER HAWKS (2-10, 0-0, 0-10 Away)* | - | | | | |
| February 28, 2043 | @ Maine Black Bears (4-8, 0-0, 2-1 Home)* | - | | | | |
