| November 15, 2042 | @ Tulane Green Wave | L 62-77 | 0-1 | B. Strong 14 | A. Schaefer 3 | R. Burton 7 |
| November 22, 2042 | MCNEESE COWBOYS | L 73-88 | 0-2 | A. Schaefer 11 | A. Schaefer 8 | A. Schaefer 3 |
| November 25, 2042 | BRYANT BULLDOGS | W 80-72 | 1-2 | B. Strong 13 | B. Strong 5 | B. Strong 9 |
| November 29, 2042 | @ San Jose State Spartans | W 76-64 | 2-2 | A. Schaefer 16 | S. Keith 5 | K. Gilbert 10 |
| December 6, 2042 | BELMONT BRUINS | L 70-83 | 2-3 | B. Strong 17 | A. Schaefer 8 | K. Gilbert 10 |
| December 10, 2042 | @ Kansas City Kangaroos | L 77-81 | 2-4 | R. Burton 12 | A. Schaefer 9 | K. Gilbert 11 |
| December 13, 2042 | @ Bradley Braves | W 79-65 | 3-4 | B. Strong 15 | R. Burton 5 | K. Gilbert 11 |
| December 16, 2042 | COPPIN STATE EAGLES | W 69-60 | 4-4 | K. Gilbert 16 | S. Keith 3 | K. Gilbert 11 |
| December 20, 2042 | @ Mercer Bears | L 58-75 | 4-5 | D. Swoger 12 | A. Schaefer 3 | B. Strong 7 |
| December 23, 2042 | @ Georgia Bulldogs | L 68-77 | 4-6 | A. Schaefer 13 | K. Gilbert 5 | K. Gilbert 7 |
| December 28, 2042 | MONMOUTH HAWKS | W 90-79 | 5-6 | G. Larson 15 | A. Schaefer 4 | K. Gilbert 12 |
| January 4, 2043 | @ SIU Edwardsville Cougars* | L 72-90 | 5-7 | S. Keith 11 | A. Schaefer 3 | K. Gilbert 7 |
| January 6, 2043 | @ Eastern Illinois Panthers* | W 76-70 | 6-7 | R. Burton 16 | B. Strong 4 | K. Gilbert 12 |
| January 9, 2043 | @ Southern Indiana Screaming Eagles* | L 76-81 | 6-8 | B. Strong 23 | B. Strong 3 | B. Strong 7 |
| January 11, 2043 | @ Tennessee Tech Golden Eagles* | L 70-85 | 6-9 | K. Gilbert 19 | D. Smith 3 | K. Gilbert 5 |
| January 13, 2043 | LINDENWOOD LIONS* | W 77-64 | 7-9 | A. Schaefer 14 | A. Schaefer 5 | K. Gilbert 10 |
| January 18, 2043 | SIU EDWARDSVILLE COUGARS* | W 70-67 | 8-9 | A. Schaefer 12 | D. Smith 3 | K. Gilbert 5 |
| January 20, 2043 | SE MISSOURI STATE REDHAWKS* | L 78-86 | 8-10 | S. Keith 15 | A. Schaefer 5 | B. Strong 6 |
| January 25, 2043 | LITTLE ROCK TROJANS* | W 87-77 | 9-10 | D. Smith 14 | D. Smith 5 | K. Gilbert 8 |
| January 27, 2043 | EASTERN ILLINOIS PANTHERS* | L 73-78 | 9-11 | K. Gilbert 17 | A. Schaefer 6 | T. Strauss 7 |
| January 30, 2043 | @ Morehead State Eagles* | L 68-75 | 9-12 | B. Strong 22 | A. Schaefer 3 | K. Gilbert 9 |
| February 3, 2043 | TENNESSEE STATE TIGERS* | L 81-91 | 9-13 | A. Schaefer 14 | S. Keith 5 | K. Gilbert 8 |
| February 6, 2043 | @ Little Rock Trojans* | W 71-61 | 10-13 | A. Schaefer 18 | D. Smith 4 | K. Gilbert 17 |
| February 8, 2043 | UT MARTIN SKYHAWKS* | W 90-77 | 11-13 | K. Gilbert 17 | B. Strong 5 | B. Strong 6 |
| February 15, 2043 | @ Lindenwood Lions* | L 70-86 | 11-14 | A. Schaefer 14 | A. Schaefer 4 | B. Strong 7 |
| February 17, 2043 | @ SE Missouri State Redhawks* | L 65-81 | 11-15 | A. Schaefer 14 | D. Smith 5 | K. Gilbert 8 |
| February 20, 2043 | SOUTHERN INDIANA SCREAMING EAGLES* | L 71-84 | 11-16 | K. Gilbert 13 | D. Smith 7 | K. Gilbert 5 |
| February 22, 2043 | MOREHEAD STATE EAGLES* | L 73-82 | 11-17 | S. Keith 19 | A. Schaefer 3 | B. Strong 5 |
| March 1, 2043 | @ Tennessee State Tigers* | L 70-86 | 11-18 | B. Strong 15 | R. Burton 4 | K. Gilbert 7 |
| March 5, 2043 | @ Morehead State Eagles OVC Tournament | W 78-76 | 12-18 | B. Strong 19 | K. Gilbert 3 | K. Gilbert 10 |
| March 6, 2043 | @ Eastern Illinois Panthers OVC Tournament | L 65-84 | 12-19 | R. Burton 12 | A. Schaefer 3 | G. Larson 9 |
