| November 16, 2042 | @ #4 North Carolina Tar Heels | L 49-87 | 0-1 | T. Houck 11 | L. Mercier 3 | E. Ramirez 7 |
| November 21, 2042 | @ Ole Miss Rebels Charleston Classic | L 88-101 | 0-2 | E. Ramirez 16 | R. Garber 5 | E. Ramirez 9 |
| November 24, 2042 | @ Oregon State Beavers | L 71-79 | 0-3 | B. Kolb 26 | R. Garber 4 | S. Taylor 7 |
| November 29, 2042 | PRESBYTERIAN BLUE HOSE | W 75-73 | 1-3 | S. Taylor 14 | D. Schaefer 4 | T. Houck 6 |
| December 1, 2042 | PORTLAND STATE VIKINGS | L 76-79 | 1-4 | E. Ramirez 19 | T. Houck 3 | E. Ramirez 10 |
| December 7, 2042 | @ Princeton Tigers | L 72-83 | 1-5 | B. Kolb 14 | R. Garber 6 | E. Ramirez 6 |
| December 9, 2042 | NEW HAMPSHIRE WILDCATS | W 86-76 | 2-5 | T. Houck 23 | R. Garber 4 | E. Ramirez 14 |
| December 13, 2042 | NEVADA WOLFPACK | L 61-88 | 2-6 | E. Ramirez 20 | T. Houck 3 | E. Ramirez 11 |
| December 23, 2042 | SEATTLE REDHAWKS | W 85-68 | 3-6 | T. Houck 20 | R. Garber 8 | E. Ramirez 10 |
| December 26, 2042 | @ UCLA Bruins (5-5, 0-0, 4-3 Home)* | - | | | | |
| December 28, 2042 | MINNESOTA GOLDEN GOPHERS (9-2, 0-0, 2-0 Away)* | - | | | | |
| January 2, 2043 | @ Michigan Wolverines (4-5, 0-0, 4-2 Home)* | - | | | | |
| January 4, 2043 | OREGON DUCKS (4-5, 0-0, 0-2 Away)* | - | | | | |
| January 9, 2043 | @ Northwestern Wildcats (5-6, 0-0, 2-3 Home)* | - | | | | |
| January 11, 2043 | PURDUE BOILERMAKERS (10-1, 0-0, 0-0 Away)* | - | | | | |
| January 16, 2043 | OHIO STATE BUCKEYES (4-5, 0-0, 0-1 Away)* | - | | | | |
| January 18, 2043 | MICHIGAN STATE SPARTANS (7-3, 0-0, 1-3 Away)* | - | | | | |
| January 23, 2043 | @ Iowa Hawkeyes (9-1, 0-0, 4-0 Home)* | - | | | | |
| January 25, 2043 | MARYLAND TERRAPINS (7-3, 0-0, 1-2 Away)* | - | | | | |
| January 30, 2043 | @ Penn State Nittany Lions (6-3, 0-0, 5-0 Home)* | - | | | | |
| February 1, 2043 | @ Wisconsin Badgers (5-4, 0-0, 5-2 Home)* | - | | | | |
| February 6, 2043 | @ Rutgers Scarlet Knights (8-1, 0-0, 8-0 Home)* | - | | | | |
| February 8, 2043 | @ USC Trojans (8-2, 0-0, 6-0 Home)* | - | | | | |
| February 13, 2043 | ILLINOIS FIGHTING ILLINI (7-2, 0-0, 2-2 Away)* | - | | | | |
| February 15, 2043 | INDIANA HOOSIERS (7-4, 0-0, 1-3 Away)* | - | | | | |
| February 20, 2043 | NEBRASKA CORNHUSKERS (3-6, 0-0, 0-2 Away)* | - | | | | |
| February 22, 2043 | @ Ohio State Buckeyes (4-5, 0-0, 4-3 Home)* | - | | | | |
| February 27, 2043 | UCLA BRUINS (5-5, 0-0, 0-1 Away)* | - | | | | |
| March 1, 2043 | @ Illinois Fighting Illini (7-2, 0-0, 5-0 Home)* | - | | | | |
